Gene methylation study in plant model system
DNA methylation is a fundamental process in gene regulation. However, methylation in plants and animals exhibits distinct patterns, and reprogramming of developmental methylation occurs in different ways. Funded by the Marie Skłodowska-Curie Actions programme, the EPIC project aims to perform a state-of-the-art study of DNA methylation using the plant model system Marchantia polymorpha. The application of high-throughput single-cell methylomics and transcriptomics, combined with innovative molecular techniques, will allow the identification of the developmental processes and epigenetic players involved in the gene methylation reprogramming process. Next, the researchers will investigate the methylation targeting mechanism using genetically modified plant cell lines to confirm the role of gene methylation in transcriptional regulation and development.
Fields of science
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding SchemeHORIZON-AG-UN - HORIZON Unit Grant
92037 La Jolla
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