Project description
Magnetic nanoparticles for cancer diagnosis and therapy
With cancer remaining the second leading cause of death worldwide, there is an obvious need for improved diagnostic and treatment approaches. Nanotechnology provides great opportunities for the targeted delivery and the enhanced efficacy of therapeutic agents to target cells. Magnetic nanoparticles additionally can be used for hyperthermia therapy of cancer while they can also function as contrast agents for magnetic resonance imaging. Funded by the Marie Skłodowska-Curie Actions programme, the ProteNano-MAG project introduces an eco-friendly synthesis route of magnetic nanoparticles for cancer. The approach uses bio-inspired simplified engineered proteins as templates, with an ultimate goal of improving the diagnosis and treatment of cancer.
Objective
The key goals of “ProteNano-MAG” are: (a) the training of a talented researcher, Dr. Lourdes Marcano, in the fast-growing field of science, technology and industrial applications of nanomedicine, where the host and partner institutions have critical knowledge and expertise; and, (b) the design, development and optimisation of eco-friendly synthesis routes using bioinspired simplified engineered proteins as templates for the preparation of magnetic nanoparticles for effective diagnosis and therapeutic intervention in cancer treatment. The interdisciplinary training program includes protein engineering, preparation of magnetic nanomaterials, characterization including sophisticated synchrotron-related techniques, in-vitro studies, magnetic resonance imaging and implementation for hyperthermia applications.
The fellow is a talented researcher who has gained much expertise in biological synthesis mediated by magnetotactic bacteria (natural systems which are inspiration to “ProteNano-MAG”) and structural and magnetic characterization of single-domain magnetic nanoparticles during her undergraduate and postgraduate career. To further boost her career, she needs to gain expertise in alternative routes for the preparation of magnetic nanomaterials, design and characterization of recombinant simplified protein systems and state-of-the-art techniques such as space-resolved X-ray fluorescence and absorption spectroscopies, fields in which the CIC biomaGUNE and the two secondment’ co-hosts, the ESRF and the Universität Bayreuth, have a world-recognised expertise. Additionally, through the six-month placement at Resonant Circuits Ltd., the fellow will gain additional high-level training in magnetic hyperthermia for the medical/industrial application of the prepared magnetic nanoparticles. This multidisciplinary project will also increase her supervision experience, project and intellectual property management expertise, and research funding and proposal writing skills.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences medical biotechnology nanomedicine
- engineering and technology nanotechnology nano-materials
- natural sciences physical sciences optics spectroscopy
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
20009 San Sebastian
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.