Project description
Living tissue manufacturing using symbiotic materials
The EU-funded PRISM-LT project will use a hybrid living materials concept to create a flexible platform for living tissue manufacturing. The innovative bio-ink will contain stem cells integrated into a supporting matrix with engineered helper bacteria or yeast cells. The bioprinting process will produce a 3D patterned structure where stem cells could be induced to differentiate into different lineages. The directed stimulation of differentiating stem cells will force them to produce lineage-specific metabolites for sensing by the designer helper cells. The helper cells within the platform will then enhance localised lineage commitment to sustain differentiation stability. The project aims to implement this strategy for the development of two symbiotic materials designed for biomedical and food applications, respectively.
Fields of science
Keywords
Programme(s)
- HORIZON.3.1 - The European Innovation Council (EIC) Main Programme
Funding Scheme
EIC - EIC
Coordinator
33100 Udine
Italy
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Participants (4)
412 96 Goteborg
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6525 XZ Nijmegen
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Participation ended
413 46 Goteborg
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
412 77 Goteborg
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Partners (1)
G12 8QQ Glasgow
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