Impact of cell shapes on cell behaviour and fate

Project Information

SHAPINCELLFATE

Grant agreement ID: 101071470

DOI

10.3030/101071470

EC signature date 6 March 2023

Start date 1 April 2023

End date 31 March 2029

Funded under

• European Research Council (ERC)

Total cost

€ 10 834 795,00

EU contribution

€ 10 834 795,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

Data Management plan

Publications

Peer reviewed articles (7)

Novel selective inhibitors of macropinocytosis-dependent growth in pancreatic ductal carcinoma

Author(s): Brambillasca S, Cera MR, Andronache A, Dey SK, Fagá G, Fancelli D, Frittoli E, Pasi M, Robusto M, Varasi M, Scita G, Mercurio C.
Published in: Biomedicine and Pharmacotherapy, 2024, ISSN 0753-3322
Publisher: Elsevier
DOI: 10.1016/j.biopha.2024.116991

Rigidity percolation and active advection synergize in the actomyosin cortex to drive amoeboid cell motility

Author(s): Juan Manuel García-Arcos, Johannes Ziegler, Silvia Grigolon, Loïc Reymond, Gaurav Shajepal, Cédric J. Cattin, Alexis Lomakin, Daniel J. Müller, Verena Ruprecht, Stefan Wieser, Raphael Voituriez, Matthieu Piel
Published in: Developmental Cell, Issue 59, 2024, ISSN 1534-5807
Publisher: Elsevier BV
DOI: 10.1016/j.devcel.2024.06.023

A planar polarized MYO6-DOCK7-RAC1 axis promotes tissue fluidification in mammary epithelia

Author(s): Menin L, Weber J, Villa S, Martini E, Maspero E, Niño CA, Cancila V, Poli A, Maiuri P, Palamidessi A, Frittoli E, Bianchi F, Tripodo C, Walters KJ, Giavazzi F, Scita G, Polo S.
Published in: Cell Reports, 2023, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2023.113001

Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer

Author(s): Di Chiaro P, Nacci L, Arco F, Brandini S, Polletti S, Palamidessi A, Donati B, Soriani C, Gualdrini F, Frigè G, Mazzarella L, Ciarrocchi A, Zerbi A, Spaggiari P, Scita G, Rodighiero S, Barozzi I, Diaferia GR, Natoli G.
Published in: Cancer Cell, 2024, ISSN 1535-6108
Publisher: Cell Press
DOI: 10.1016/j.ccell.2024.02.017

A tripartite organelle platform links growth factor receptor signaling to mitochondrial metabolism

Author(s): Mesa D, Barbieri E, Raimondi A, Freddi S, Miloro G, Jendrisek G, Caldieri G, Quarto M, Schiano Lomoriello I, Malabarba MG, Bresci A, Manetti F, Vernuccio F, Abdo H, Scita G, Lanzetti L, Polli D, Tacchetti C, Pinton P, Bonora M, Di Fiore PP, Sigismund S.
Published in: Nature Communications, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-49543-z

Tissue fluidification promotes a cGAS-STING cytosolic DNA response in invasive breast cancer.

Author(s): Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, Abdo H, Cancila V, Beznoussenko GV, Della Chiara G, Pagani M, Malinverno C, Bhattacharya D, Pisati F, Yu W, Galimberti V, Bonizzi G, Martini E, Mironov AA, Gioia U, Ascione F, Li Q, Ha
Published in: Nature Materials, 2023, ISSN 2058-8437
Publisher: Springer Nature
DOI: 10.1038/s41563-022-01431-x

Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes

Author(s): Alraies Z, Rivera CA, Delgado MG, Sanséau D, Maurin M, Amadio R, Maria Piperno G, Dunsmore G, Yatim A, Lacerda Mariano L, Kniazeva A, Calmettes V, Sáez PJ, Williart A, Popard H, Gratia M, Lamiable O, Moreau A, Fusilier Z, Crestey L, Albaud B, Legoix P, De
Published in: Nature Immunology, 2024, ISSN 1529-2916
Publisher: Springer Nature
DOI: 10.1038/s41590-024-01856-3