Objective
CombiDiag DN aims to develop an AI-data-driven peripheral biomarker based combinatorial diagnostic protocol for early stages of Alzheimers disease (AD), a major form of dementia, and to train a new generation of fellows for this interdisciplinary field. Dementia, a devastating disease of older age, is the challenge of our lifetime and one of the Societal Challenges listed by the UN Sustainable Development Goals and Horizon Europe. CombiDiag responds to this challenge to establish a much-needed DN to carry out an integrated study of minimally invasive and cost-effective peripheral biomarkers, including body fluid markers from blood, urine and saliva, and digital markers from speech, motor functions and sleep for developing the combinatorial early AD diagnostics. The consortium comprises nine academic and eight non-academic institutions across Europe, USA, Canada, and China. It synergises leading academic and industrial experts worldwide to build a triple-i research and training platform for the training of a new generation of Fellows to take early AD diagnostic research to a new level. Fellows will be trained under the Vitae Researcher Development Framework innovatively combined with the CombiDiag platform for triple-i scientific and transferable skills as well as personal quality, creative thinking, and business mind-set. The DN has a highly innovative research programme for the discovery of peripheral AD biomarkers, detection techniques, AI/data driven technology, clinical validation, and integration into trial designs. The advances in CombiDiag research will enable a case finding tool at primary care level for helping achieve improved drug discoveries, disease-modifying treatments, preventive strategies and care provision for AD. CombiDiag will deliver 10 highly-skilled, creative and entrepreneurial Fellows, setting them on a path to successful careers in academia or industry to ensure that the medical and societal challenges imposed by AD are met.
Fields of science
Keywords
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral NetworksCoordinator
18055 Rostock
Germany
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Participants (7)
80686 Munchen
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2730 Herlev
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
68330 Huningue
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
00185 Roma
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18055 Rostock
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28029 Madrid
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06100 Nice
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Partners (12)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
BEIJING
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N2L 3G1 Waterloo
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
02421 Lexington
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1736 SENNINGERBERG
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
518083 SHENZHEN
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
SO14 3EB Southampton
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
4521 Schiedlberg
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
RG6 6AH Reading
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
PL4 8AA Plymouth
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
2800 Kongens Lyngby
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
66123 Saarbrucken
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
28040 Madrid
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