PErPetuating Stemness: From single-cell analysis to mechanistic spatio-temporal models of neural stem cell dynamics

Información del proyecto

PEPS

Identificador del acuerdo de subvención: 101071786

DOI

10.3030/101071786

Fecha de la firma de la CE 27 Enero 2023

Fecha de inicio 1 Junio 2023

Fecha de finalización 31 Mayo 2029

Financiado con arreglo a

• European Research Council (ERC)

Coste total

€ 10 858 174,00

Aportación de la UE

€ 10 858 174,00

Coordinado por

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (14)

Generation and Pharmacological Manipulation of 3D‐Spheroid Cultures Derived From Zebrafish Adult Neural Stem Cells in a Droplet‐Based Microfluidic Platform

Autores: Melina Thetiot, Sébastien Sart, Delphine Cussigh, Marion Coolen, Charles N. Baroud, Laure Bally‐Cuif
Publicado en: Biology of the Cell, Edición 117, 2025, ISSN 0248-4900
Editor: Wiley
DOI: 10.1111/BOC.70007

Nature Communications

Autores: Morizet, David; Foucher, Isabelle; Alunni, Alessandro; Bally-Cuif, L
Publicado en: Nature Communications, 2024, ISSN 2041-1723
Editor: Nature Publishing group
DOI: 10.1038/S41467-024-47484-1

Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with their reactivation routes and potential

Autores: Morizet D, Foucher I, Mignerey I, Alunni A, Bally-Cuif L
Publicado en: Science Advances, 2025, ISSN 2375-2548
Editor: AAAS
DOI: 10.1126/SCIADV.ADU3189

Stem Cell Reports

Autores: Miriam Labusch; Melina Thetiot; Emmanuel Than-Trong; David Morizet; Marion Coolen; Hugo Varet; Rachel Legendre; Sara Ortica; Laure Mancini; Laure Bally-Cuif
Publicado en: Stem Cell Reports, 2023, ISSN 2213-6711
Editor: Cell Press
DOI: 10.1016/J.STEMCR.2024.02.007

Unraveling Regulatory Feedback Mechanisms in Adult Neurogenesis Through Mathematical Modelling

Autores: Diana-Patricia Danciu; Filip Z. Klawe; Laura Femmer; Ekaterina Kostina; Ana Martin-Villalba; Anna Marciniak-Czochra
Publicado en: npj Systems Biology and Applications, 2025, ISSN 2056-7189
Editor: Nature Publishing Group
DOI: 10.1038/S41540-025-00563-5

Statistical parameter identification of mixed-mode patterns from a single experimental snapshot

Autores: Alexey Kazarnikov, Robert Scheichl, Irving R. Epstein, Heikki Haario, Anna Marciniak-Czochra
Publicado en: Journal of Computational Physics, Edición 543, 2025, ISSN 0021-9991
Editor: Elsevier BV
DOI: 10.1016/J.JCP.2025.114384

Jagged-mediated lateral induction patterns Notch3 signaling within adult neural stem cell populations

Autores: Sara Ortica, Miguel Martinez Herrera, Louis Degroux, Bastian Rochette, Nicolas Dray, Laure Bally-Cuif
Publicado en: Nature Communications, Edición 17, 2026, ISSN 2041-1723
Editor: Springer Science and Business Media LLC
DOI: 10.1038/S41467-026-70478-0

Nature Communications

Autores: Leo Carl Foerster, Oguzhan Kaya, ...,Anna Marciniak-Czochra, Simon Anders, Angela Goncalves, Ana Martin-Villalba
Publicado en: Nature Communications, 2025, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/S41467-025-62528-W

Non-apoptotic caspase events and Atf3 expression underlie direct neuronal differentiation of adult neural stem cells

Autores: Frédéric Rosa; Nicolas Dray; Sébastien Bedu; Laure Bally-Cuif
Publicado en: Development, 2024, ISSN 1477-9129
Editor: The Company of Biologists
DOI: 10.1242/DEV.204381

Structured population models on Polish spaces: A unified approach including graphs, Riemannian manifolds and measure spaces to describe dynamics of heterogeneous populations

Autores: Christian Düll, Piotr Gwiazda, Anna Marciniak-Czochra, Jakub Skrzeczkowski
Publicado en: Mathematical Models and Methods in Applied Sciences, Edición 34, 2024, ISSN 0218-2025
Editor: World Scientific Pub Co Pte Ltd
DOI: 10.1142/S0218202524400037

Beyond Bayesian Inference: The Correlation Integral Likelihood Framework and Gradient Flow Methods for Deterministic Sampling

Autores: Piotr Gwiazda; Alexey Kazarnikov; Anna Marciniak-Czochra; Zuzanna Szymańska
Publicado en: Bulletin of Mathematical Biology, 2025, ISSN 1522-9602
Editor: New York, NY : Springer
DOI: 10.48550/ARXIV.2512.03122

Protocol update to: High-throughput scNMT protocol for multiomics profiling of single cells from mouse brain and pancreatic organoids

Autores: Santiago Cerrizuela, Oguzhan Kaya, Lukas P.M. Kremer, Andrea Sarvari, Tobias Ellinger, Jannes Straub, Jan Brunken, Andrés Sanz-Morejón, Aylin Korkmaz, Ana Martín-Villalba
Publicado en: STAR Protocols, Edición 6, 2025, ISSN 2666-1667
Editor: Elsevier BV
DOI: 10.1016/J.XPRO.2025.103980

Neural Stem Cell Regulation in Zebrafish

Autores: Foley, Tanya; Thetiot, Melina; Bally-Cuif, L
Publicado en: Annual Review of Genetics, 2024, ISSN 1545-2948
Editor: Annual Reviews
DOI: 10.1146/ANNUREV-GENET-111523-101949

FishFeats: streamlined quantification of multimodal labeling at the single-cell level in 3D tissues

Autores: Gaëlle Letort, Tanya Foley, Ilona Mignerey, Laure Bally-Cuif, Nicolas Dray
Publicado en: Bioinformatics, Edición 42, 2026, ISSN 1367-4803
Editor: Oxford University Press (OUP)
DOI: 10.1093/BIOINFORMATICS/BTAG105