Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces

Project Information

PushingCell

Grant agreement ID: 101071793

DOI

10.3030/101071793

EC signature date 26 April 2023

Start date 1 May 2023

End date 30 April 2029

Funded under

• European Research Council (ERC)

Total cost

€ 9 813 625,00

EU contribution

€ 9 813 625,00

Coordinated by

INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
Austria

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

napariTFM: An open-source tool for traction force microscopy and monolayer stress microscopy

Author(s): Artur Ruppel, Dennis Wörthmüller, Martial Balland, François Fagotto
Published in: PLOS Computational Biology, Issue 22, 2026, ISSN 1553-7358
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PCBI.1014045

Modelling chemotaxis of branched cells in complex environments provides insights into immune cell navigation

Author(s): Jiayi Liu, Jonathan E. Ron, Giulia Rinaldi, Ivanna Williantarra, Antonios Georgantzoglou, Ingrid de Vries, Michael Sixt, Milka Sarris, Nir S. Gov
Published in: PLOS Computational Biology, Issue 22, 2026, ISSN 1553-7358
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PCBI.1013934

Modeling mechanochemical coupling in optogenetically activated cell layers

Author(s): Dennis Wörthmüller, Falko Ziebert, Ulrich S. Schwarz
Published in: Biophysical Journal, Issue 125, 2026, ISSN 0006-3495
Publisher: Elsevier BV
DOI: 10.1016/J.BPJ.2025.10.002

Curvature Instability of an Active Gel Growing on a Wavy Membrane

Author(s): Kristiana Mihali, Dennis Wörthmüller, Pierre Sens
Published in: Physical Review Letters, Issue 136, 2026, ISSN 0031-9007
Publisher: American Physical Society (APS)
DOI: 10.1103/XZKP-F581

Spatiotemporal coupling of caveolae mechanosensing and RhoA-GEFs regulates cell polarity and directional migration

Author(s): Vibha Singh, Victor Breton, Christine Viaris de Lesegno, Anne-Sophie Macé, Philippe Bun, Cédric M. Blouin, Amit Singh Vishen, Pierre Sens, Christophe Lamaze
Published in: Nature Communications, Issue 17, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-67090-Z

Substrate heterogeneity promotes cancer cell dissemination through interface roughening

Author(s): Zuzana Dunajova; Saren Tasciyan; Juraj Majek; Jack Merrin; Erik Sahai; Michael Sixt; Edouard Hannezo
Published in: Biorxiv, 2025, ISSN 2692-8205
Publisher: Biorxiv
DOI: 10.1101/2025.05.20.655037

Optogenetic and chemical genetic tools for rapid repositioning of vimentin intermediate filaments

Author(s): Milena Pasolli, Joyce C.M. Meiring, James P. Conboy, Gijsje H. Koenderink, Anna Akhmanova
Published in: Journal of Cell Biology, Issue 224, 2025, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/JCB.202504004

Nature Immunology

Author(s): Patricia Reis-Rodrigues; Mario J. Avellaneda; Nikola Canigova; Florian Gaertner; Kari Vaahtomeri; Michael Riedl; Ingrid de Vries; Jack Merrin; Robert Hauschild; Yoshinori Fukui; Alba Juanes Garcia; Michael Sixt
Published in: Nature Immunology, Issue 26, 2025, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/S41590-025-02211-W

Thesis and dissertations (1)

Coordination of protrusive forces in immune cell migration

Author(s): Reis-Rodrigues, Patricia
Published in: 2025
Publisher: Institute of Science and Technology
DOI: 10.15479/AT-ISTA-20149