Description du projet
Des nanomatériaux magnétiques innovants pour la recherche et le traitement du cancer
Financé par le programme Actions Marie Skłodowska-Curie, le projet STRIKE a pour ambition de mettre en place un réseau de recherche et de formation dans le domaine de la nanomédecine/médecine de précision, ouvrant ainsi la voie à une nouvelle génération de jeunes chercheurs multidisciplinaires à l’esprit d’entreprise et innovant. Il mettra l’accent sur la conception et la synthèse de matériaux magnétiques nanostructurés pour le développement de nanothérapies sensibles aux champs magnétiques destinées à la thérapie combinatoire de l’ostéosarcome. En outre, les nanomatériaux mis au point seront étudiés pour une utilisation dans des applications de biopsie liquide chez les patientes atteintes d’un cancer du sein. Les objectifs de STRIKE comprennent la formation de huit doctorants hautement qualifiés et le renforcement de la coopération interdisciplinaire au sein des réseaux européens de recherche sur la nanomédecine et la médecine de précision.
Objectif
STRIKE-DN will raise excellence in research and training in nanomedicine/precision medicine creating new generation of entrepreneurial and innovative multidisciplinary doctoral candidates. New experimental aspects on design and synthesis of nanostructured magnetic materials will be applied to the development of innovative magnetic field-responsive nanotherapeutics for osteosarcoma (OS) combinational therapy. Moreover, the peculiar features of STRIKE nanomaterials will be exploited for liquid biopsy using biological samples of BRCA+ breast cancer (BC) patients. The cooperation among outstanding universities, research institutes and industries will provide the DCs with trans-national exchanges and the most innovative research trainings in novel anticancer therapeutic strategies, including in vivo biological evaluation, imaging in OS and early diagnosis in BC. STRIKE will provide enhanced career perspectives in academic and non-academic sectors for 8 DCs in highly innovative fields by interdisciplinary mobility among 12 institutes/companies in 8 EU countries. STRIKE aims to: 1) develop 8 highly skilled employable doctoral candidates; 2) enhance interdisciplinary capacity and cooperation within the EU nanomedicine and precision medicine research networks; 3) strengthen EU’s competitiveness and growth in nanomedicine and precision medicine through the translation of the consortium research/innovation outputs. The consortium will fulfill its goals through: a) achieving research excellence; b) providing a complete cutting edge research and innovation training program with some of the European top research institutes and industry partners; c) hosting interdisciplinary and commercial workshops, seminars and outreach events; d) maximizing knowledge transfer using Open Science and patents; e) delivering highly trained professionals, whose profiles fit within the requirements of academia, industry and public/private institutions, fostering their employability and promoting the innovation of EU research.
Champ scientifique
Mots‑clés
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Régime de financement
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral NetworksCoordinateur
98122 Messina
Italie