Quality Control of the Mitochondrial Gene Expression System in Health and Disease

Project Information

MITGEST

Grant agreement ID: 101072515

DOI

10.3030/101072515

EC signature date 18 July 2022

Start date 1 October 2022

End date 31 January 2027

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 557 900,80

Coordinated by

MIEDZYNARODOWY INSTYTUT MECHANIZMOW I MASZYN MOLEKULARNYCH POLSKIEJ AKADEMII NAUK
Poland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (1)

List of proteins involved in the degradation of damaged mitochondrial mRNAs

Websites, patent fillings, videos etc. (2)

Mito comic book
MITGEST website

Publications

Peer reviewed articles (7)

Is Drp1 a link between mitochondrial dysfunction and inflammation in Alzheimer’s disease?

Author(s): Oualid Sbai, Veronica Bazzani, Shreya Tapaswi, Joshua McHale, Carlo Vascotto, Lorena Perrone
Published in: Frontiers in Molecular Neuroscience, Issue 16, 2023, ISSN 1662-5099
Publisher: Frontiers Media SA
DOI: 10.3389/FNMOL.2023.1166879

Small but mighty: mitochondrial DNA at the centre of retrograde signalling

Author(s): Eve Harding, Veronica Bazzani, Carlo Vascotto
Published in: Cell Communication and Signaling, Issue 24, 2026, ISSN 1478-811X
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S12964-026-02858-4

Decoding the Enigma: Translation Termination in Human Mitochondria

Author(s): Annika Krüger, Daria Kovalchuk, Dmitrii Shiriaev, Joanna Rorbach
Published in: Human Molecular Genetics, Issue 33, 2024, ISSN 0964-6906
Publisher: Oxford University Press (OUP)
DOI: 10.1093/HMG/DDAE032

FALCON-qPCR: a new method for the quantification of oxidative lesions in mitochondrial DNA

Author(s): Veronica Bazzani, Eve Harding, Szymon Balinski, Mara Equisoain Redin, Dario Alessi, Pierfrancesco Del Mestre, Walter Baratta, Daniela Cesselli, Antonio Paolo Beltrami, Michał Turek, Umberto Baccarani, Carlo Vascotto
Published in: Bioanalysis, Issue 17, 2026, ISSN 1757-6180
Publisher: Informa UK Limited
DOI: 10.1080/17576180.2025.2608757

RNA degradation in human mitochondria: the journey is not finished

Author(s): Giulia Santonoceto, Aneta Jurkiewicz, Roman J Szczesny
Published in: Human Molecular Genetics, Issue 33, 2024, ISSN 0964-6906
Publisher: Oxford University Press (OUP)
DOI: 10.1093/HMG/DDAE043

Mitochondrial DNA replication is regulated by endoplasmic reticulum-mitochondrial contact sites, the mitochondrial calcium uniporter, and manganese

Author(s): Amaia Lopez de Arbina, Angelica Zamudio-Ochoa, Mikel Muñoz-Oreja, Diego Perez-Rodriguez, Laura Mosqueira-Martín, Rebecca Lasalandra, Marina Villar-Fernandez, Uxoa Fernandez-Pelayo, Laura Rodriguez-Gomez, Seungtae Lee, Francisco Gil-Bea, Nerea Osinalde, Ainara Vallejo-Illaramendi, Dmitry Temiakov, Antonella Spinazzola, Ian J Holt
Published in: Nucleic Acids Research, Issue 54, 2026, ISSN 0305-1048
Publisher: Oxford University Press (OUP)
DOI: 10.1093/NAR/GKAG233

Cyclophilin D is a new non-canonical substrate of the mitochondrial intermembrane space assembly pathway

Author(s): Mara Equisoain Redin, Veronica Bazzani, Eve Harding, Joshua McHale, Carlo Vascotto
Published in: Journal of Biological Chemistry, Issue 301, 2025, ISSN 0021-9258
Publisher: Elsevier BV
DOI: 10.1016/J.JBC.2025.110883