Functional Nano-Scaffolds for Regenerative Medicine

Informations projet

NANOREMEDI

N° de convention de subvention: 101072645

DOI

10.3030/101072645

Date de signature de la CE 6 Juillet 2022

Date de début 1 Septembre 2022

Date de fin 31 Août 2026

Financé au titre de

• Marie Skłodowska-Curie Actions (MSCA)

Coût total

Aucune donnée

Contribution de l’UE

€ 3 413 325,60

Coordonné par

UNIVERSITA DEGLI STUDI DI MILANO
Italy

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Other (1)

Consortium web-site creation and scientific blog

Web site/flyer/broshure prepared

Data Management Plan (1)

Data Management plan submitted

2 Management plans prepared at months 13/45All Beneficiaries involved

Documents, reports (1)

Recruitment advertising publication

Recruitment advertising publication in months 1-3All beneficiaries involvedAdvertisements on EURAXESS; APRE national portals;FindAPhD; Academic Positions and all Beneficiaries web-sites

Publications

Conference proceedings (57)

Characterization of complex electrospun matrices through hyperspectral Raman imaging

Auteurs: Matteo Bottiglieri, Mohammad Amini, Maria L. Gelmi, Alexander M. Bittner
DOI: 10.5281/ZENODO.14856845

Peptide-based nanomaterials for tissue regeneration

Auteurs: Nursu Erdogan
Éditeur: zenodo
DOI: 10.5281/ZENODO.18497103

Insights into Non-Natural Peptide Aggregation in Biocompatible Materials: A Classical and Accelerated Molecular Dynamics Study

Auteurs: Ahmed Saeed, Alessandro Contini, Carlos Enrique Alemàn
DOI: 10.5281/ZENODO.16315905

Bioinspired Peptide-Polymer Coatings for Biomedical Applications

Auteurs: Nallathambi, Abinaya; GENTA, IDA; Reches, Meital
Publié dans: 2025
DOI: 10.5281/ZENODO.15480118

Synthesis of tetraphenylethene L-phenylalanine derivatives and their application in aggregation induced fluorescent peptide materials Creators

Auteurs: A. I. Antoniou, M. Pesenti, D.S. Shenoy, S. Crespi, M. Penconi, A. Bossi, S. Pellegrino
DOI: 10.5281/ZENODO.14855585

Structural characterization of pure peptide electrospun fibers

Auteurs: Konstantina Mitropoulou, Meital Reches, Alexander M. Bittne
Éditeur: zenodo
DOI: 10.5281/ZENODO.14824623

Self-Assembling Lipopeptide Hydrogels as Functional Scaffolds for Tissue Regeneration

Auteurs: Dhriti Shenoy, Michela Pesenti, Kaliroi Peqini, Emeline Perrier-Groult , Cécile Echalier, Gilles Subra, Sara Pellegrino
Éditeur: zenodo
DOI: 10.5281/ZENODO.17831143

MANUFACTURING OF SMALL DIAMETER VASCULAR GRAFTS FOR REGENERATIVE PURPOSES

Auteurs: Erdogan Nursu; Shenoy Santosh Dhriti; Chiesa Enrica; Bittner Alexander; Pellegrino Sara; Genta Ida
DOI: 10.5281/ZENODO.18496808

Synthesis of peptidomimetics using Diaryl-beta-Amino acids for the preparation of smart materials

Auteurs: Dulce A. Quintana - Romero , Raff a ella Bucci , Merve Gul, Maria M. Pérez - Madrigal, Carlos Al emán, M . Luisa Gelmi
Éditeur: zenodo
DOI: 10.5281/ZENODO.14853154

Electrospinning of short peptides and characterization through Hyperspectral Raman spectroscopy

Auteurs: Matteo Bottiglieri, Konstantina Mitropoulou, Maria L. Gelmi and Alexander M. Bittner
DOI: 10.5281/ZENODO.14856710

Develop and Apply Suitable Methods to Perform Molecular Modelling and Perform Conformational Searches and In-Silico Aggregation Studies

Auteurs: Saeed Ahmed, Alessandro Contini, Carlos Enrique Aleman
DOI: 10.5281/ZENODO.16323992

Playing with Non-Coded Amino Acids to develop Bioinspired Molecular Architectures

Auteurs: Bucci, Raffaella, Maria Luisa Gelmi, Sara Pellegrino
Éditeur: zenodo
DOI: 10.5281/ZENODO.14851650

Bioinspired Peptide-Polymer Coatings for Antifouling and Biomedical Applications

Auteurs: Abinaya Nallathambi; Ida Genta; Meital Reches
DOI: 10.5281/ZENODO.15480118

Self-assembling lipopeptide hydrogels: Bioactive scaffolds for osteochondral tissue regeneration

Auteurs: Dhriti Shenoy, Michela Pesenti, Kaliroi Peqini, Emeline Perrier-Groult, Cécile Echalier, Gilles Subra, Sara Pellegrino
Éditeur: zenodo
DOI: 10.5281/ZENODO.18485091

Influnce of drug-polymer interactions on release kinetics of PLGA and PLAPEG Nanoparticles

Auteurs: Merve Gul, Ida Genta, Maria M. Perez Madrigal, Carlos Aleman, Enrica Chiesa
DOI: 10.5281/ZENODO.16083265

"Synthesis of a peptidomimetics library for the stabilization of supermagnetic nanoparticles for the transdermal delivery. ""Noncanonical amino acids (ncAAs): Tools for Biological and Biophysical Investigations"

Auteurs: Giulia Servalli, Dulce A. Quintana-Romero, Tommaso Gandini, Raffaella Bucci, Maria Luisa Gelmi
DOI: 10.5281/ZENODO.14853251

Bioengineering of lipopeptides for therapeutic applications

Auteurs: Dhriti Shenoy, Michela Pesenti, Kaliroi Peqini, Nicolas Simon, Stefania Crespi, Cécile Echalier, Gilles Subra, Sara Pellegrino
DOI: 10.5281/ZENODO.16090099

Self-assembledpeptide-based coating for biomedical applications

Auteurs: Sowmya Chivukula, Enrica Chiesa, Ida Genta, Meital Reches
Publié dans: 2025
DOI: 10.5281/ZENODO.16338936

Pyrrole-Pyrazole Peptidomimetics: From Cycloaddition to Smart Nanomaterials

Auteurs: M. Bottiglieri, M. L. Gelmi, A. M. Bittner
DOI: 10.5281/ZENODO.15854451

Synthesis of peptidomimetics using Diaryl-β-amino acids for the preparation of smart materials

Auteurs: Dulce A. Quintana-Romero, R. Bucci, M.L. Gelmi
DOI: 10.5281/ZENODO.14853190

Diving into the blue: Synthetic methodologies toward aggregation induced fluorescent peptide materials

Auteurs: A.I. Antoniou, M . Pesenti, M. Penconi, D .S. Shenoy, S . Crespi , A . Bossi, S. Pellegrino
Éditeur: zenodo
DOI: 10.5281/ZENODO.14855564

Electrochemical response of α/β-peptides: Influence of the peptide length, stereochemistry and self-assembly on the performance of peptide-based electrochemical sensors

Auteurs: Dulce A. Quintana-Romero, Merve Gul, Adrián Fontana-Escartín, M. Luisa Gelmi, Maria M. Pérez-Madrigal, Raffaella Bucci, Carlos Alemán
Publié dans: 2026
Éditeur: zenodo
DOI: 10.5281/ZENODO.18607912

Influnce of drug-polymer interactions on release kinetics of PLGA and PLAPEG Nanoparticles

Auteurs: Gul, Merve; GENTA, IDA; Perez Madrigal, Maria M.; Aleman, Carlos; CHIESA, ENRICA
Publié dans: 2025
DOI: 10.5281/ZENODO.16083265

Silylated peptides as building blocks for material synthesis using sol-gel polymerization and self-assembly

Auteurs: Mehmet B. Karakaplan, Vinay S. Tiwari, Omer Agazani, Cécile Echalier, Gilles Subra, Meital Reches
DOI: 10.5281/ZENODO.16316211

PEPTIDE-DECORATED ELECTROSPUN SCAFFOLDS AS VASCULAR GRAFT

Auteurs: Erdogan Nursu; Shenoy Santosh Dhriti; Chiesa Enrica; Bittner Alexander; Pellegrino Sara; Genta Ida
DOI: 10.5281/ZENODO.15911140

Peptide Electrospinning with a Biocompatible Polymer for Biomedical Applications

Auteurs: Nallathambi, Abinaya; Genta Ida, Reches Meital
Éditeur: zenodo
DOI: 10.5281/ZENODO.12697491

Investigation of electrochemical response of α/β-peptides: Influence of the peptide length, stereochemistry and self-assembly on the performance of peptide-based electrochemical sensors

Auteurs: Merve Gul, Dulce A. Quintana-Romero, Adrián Fontana- Escartín, Maria Luisa Gelmi, Maria M. Pérez-Madrigal, Enrica Chiesa, Raffaella Bucci , Carlos Alemán
DOI: 10.5281/ZENODO.16087215

ESEM and AFM structural characterization of short peptide electrospun fibers

Auteurs: Mitropoulou, Konstantina
DOI: 10.5281/ZENODO.14809558

Late-stage peptide functionalization in the development of aggregation induced emissive smart materials

Auteurs: M. Pesenti, A.I. Antoniou, D.S. Shenoy, M. Penconi, S. Crespi, A. Bossi, S. Pellegrino
Éditeur: zenodo
DOI: 10.5281/ZENODO.14855549

Cell - laden scaffolds for osteochondral repai

Auteurs: Lauren Roberts, Cécile Echalier , Emeline P errier - Groult , Danièle Nöel, Sara Pellegrino, Gilles Subra
Éditeur: zenodo
DOI: 10.5281/ZENODO.10687294

Manufacturing of composite electrospun VGs for regenerative purposes

Auteurs: Nursu ERDOĞAN, Ida GENTA, Enrica CHIESA, Alexander BITTNER
DOI: 10.5281/ZENODO.16319745

Synthesis and applications of TPE-based unnatural amino acids characterized by aggregation induced emission. Creators

Auteurs: M. Pesenti, A.I. Antoniou, D.S. Shenoy, M. Penconi , S. Crespi , A. Bossi, S. Pellegrino
Éditeur: zenodo
DOI: 10.5281/ZENODO.14855492

ENHANCED SAMPLING METHODS FOR PEPTIDE CONFORMATIONAL ANALYSIS: STRENGTHS, LIMITATIONS, AND APPLICATIONS

Auteurs: Crescenzo Coppa, Ahmed Saeed, Alessandro Contini
Éditeur: zenodo

Fabrication of off-the-shelf biodegradable small-caliber Vascular Graftwith improved microbiological and regenerative features

Auteurs: ABINAYA NALLATHAMBI
Éditeur: zenodo
DOI: 10.5281/ZENODO.16412716

Sol-gel: a bioorthogonal chemistry for customized biomimetic matrices

Auteurs: ECHALIER, CECILE, SUBRA, Gilles
Publié dans: 2026
Éditeur: zenodo
DOI: 10.5281/ZENODO.18484646

Smart Functionalization of Pyrrole-Pyrazole Peptidomimetics for Tailored Nanomaterials

Auteurs: Bottiglieri, Matteo
DOI: 10.5281/ZENODO.14849061

Design and applications of smart nanocarriers to achieve controlled release of antimicrobial agents for regenerative medicine.

Auteurs: Merve Gul
DOI: 10.5281/ZENODO.16363968

Antifouling Polyurethane Vascular Grafts to Prevent Implant Failure

Auteurs: Nallathambi, Abinaya, Reches, Meital GENTA, IDA, CHIESA, ENRICA
DOI: 10.5281/ZENODO.14509444

MSC-laden Scaffolds for Osteochondral Repair

Auteurs: Roberts, L.
DOI: 10.5281/ZENODO.16360812

Insights into Non-Natural Peptide Aggregation in Biocompatible Materials: A Classical and Accelerated Molecular Dynamics Study

Auteurs: Ahmed, Saeed
Publié dans: 2025
DOI: 10.5281/ZENODO.16315905

Self-assembled bifunctional peptide-based coating for biomedical applications

Auteurs: Sowmya Chivukula, Enrica Chiesa, Ida Genta, Meital Reches
Publié dans: 2025
Éditeur: zenodo
DOI: 10.5281/ZENODO.16337677

Silylated Biopolymer-based Hydrogels for Osteochondral Repair

Auteurs: Roberts, Lauren
Éditeur: zenodo
DOI: 10.5281/ZENODO.14853018

Pure peptide electrospun fibres: synthesis, analysis, dissolution

Auteurs: Konstantina Mitropoulou, Meital Reches, Alexander M. Bittner
DOI: 10.5281/ZENODO.13773974

Designing self-assembling lipopeptide for tissue regeneration

Auteurs: Dhriti Shenoy, Lauren Roberts, Michela Pesenti, Kaliroi Peqini, Stefania Crespi, Cécile Echalier, Gilles Subra, Sara Pellegrino
Publié dans: Proceedings of the 37th European Peptide Symposium, 2024
Éditeur: The European Peptide Society
DOI: 10.17952/37EPS.2024.P2212

From hybrid peptides to structured bioorganic-inorganic materials

Auteurs: Qassem, Ali
DOI: 10.5281/ZENODO.14846404

ESEM and AFM structural characerization of short peptide electrospun fibers

Auteurs: Mitropoulou, Konstantina
DOI: 10.5281/ZENODO.14823922

Self-Assembling Lipopeptide Hydrogels: Building Bioactive Scaffolds for Next- Gen Tissue Regeneration

Auteurs: Dhriti Shenoy, Michela Pesenti, Kaliroi Peqini, Emeline Perrier-Groult, Cécile Echalier, Gilles Subra, Sara Pellegrino
DOI: 10.5281/ZENODO.16317090

A PRELIMINARY STUDY OF PEPTIDE DECORATED ELECTROSPUN SCAFFOLDS AS VASCULAR GRAFTS

Auteurs: Erdogan Nursu, Shenoy Santosh Dhriti, Chiesa Enrica, Bittner Alexander, Pellegrino Sara, Genta Ida
Éditeur: zenodo
DOI: 10.5281/ZENODO.11477050

Synthesis of peptidomimetics using Diaryl-β amino acids for the preparation of smart materials

Auteurs: Dulce A. Quintana - Romero , Raffaella Bucci, Merve Gul, Maria M. Pérez - Madrigal, Carlos Alemán, M . Luisa Gelmi
DOI: 10.5281/ZENODO.14853207

Elastin-Like Polypeptide Mimetics: from synthesis to material characterization

Auteurs: Bottiglieri, Matteo
DOI: 10.5281/ZENODO.14848988

Insights into Non-Natural Peptide Aggregation in Biocompatible Materials: A Classical and Accelerated Molecular Dynamics Study

Auteurs: Ahmed, Saeed
Publié dans: 2025
DOI: 10.5281/ZENODO.16315905

Self-assembled bifunctional peptide-based coating for biomedical applications

Auteurs: Sowmya Chivukula, Enrica Chiesa, Ida Genta, Meital Reches
Publié dans: 2025
DOI: 10.5281/ZENODO.16338529

Ultrathin water layers on viruses

Auteurs: A.M. Bittner, M.A. Iriarte - Alonso , J.H. Melillo , S . Cerveny , S. Chiantia
Éditeur: zenodo
DOI: 10.5281/ZENODO.148573202

pH-responsive self-assembling IKVAV-derived peptides: in silico and in vitro analysis

Auteurs: Dhriti S. Shenoy, Allegra Ascagni,Michela Pesenti, Antonia I. Antoniou, Alfonso Gautieri, Sara Pellegrino
Éditeur: zenodo
DOI: 10.5281/ZENODO.10797615

Designing self-assembling bioactive lipopeptide

Auteurs: Shenoy, D. S., Pellegrino, S., Peqini, K., Pesenti, M., Simon, N., ECHALIER, C., & SUBRA, G.
DOI: 10.5281/ZENODO.15747367

Electrochemical response of α/β-peptides: Influence of the peptide length, stereochemistry and self-assembly on the performance of peptide-based electrochemical sensors

Auteurs: Dulce A. Quintana-Romero, Merve Gul, Adrián Fontana-Escartín, M. Luisa Gelmi, Maria M. Pérez-Madrigal, Raffaella Bucci, Carlos Alemán
DOI: 10.5281/ZENODO.16267859

Cell-laden Scaffolds for Osteochondral Repair

Auteurs: Lauren Roberts, Cécile Echalier , Emeline P errier - Groult , Danièle Nöel, Sara Pellegrino, Gilles Subra
DOI: 10.5281/ZENODO.10691699

Peer reviewed articles (14)

From Dielectric to Electro-Responsive Thermoplastics: An Approach Based on Electro-Thermal Re-orientation and Charged Gas Activation

Auteurs: Gul, Merve; Fontana-Escartin, Adrián; Arnau, Marc; Sans, Jordi; Lanzalaco, Sonia,; Armelin, Elaine; Chiesa, Enrica; Genta, Ida; Perez-Madrigal, Maria; Alemán, Carlos
Publié dans: ACS Applied Polymer Materials, ISSN 2637-6105
Éditeur: ACS
DOI: 10.1021/ACSAPM.4C02610

Aggregation-Induced Enhanced Emission of Tetraphenylethene-phenylalanine Hybrids: Synthesis and Characterization

Auteurs: Antonia I. Antoniou, Michela Pesenti, Stefania Crespi, Dhriti S. Shenoy, Marta Penconi, Alberto Bossi, Sara Pellegrino
Publié dans: The Journal of Organic Chemistry, Numéro 89, 2024, ISSN 0022-3263
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/acs.joc.3c02969

Silylated peptides as building blocks for material synthesis using sol–gel polymerization

Auteurs: Mehmet B. Karakaplan, Vinay S. Tiwari, Omer Agazani, Cécile Echalier, Gilles Subra, Meital Reches
Publié dans: Faraday Discussions, 2025, ISSN 1359-6640
Éditeur: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5FD00014A

Multimodal Imaging, Drug Delivery, and On‐Board Triggered Degradation in Soft Capsule Rolling Microrobots

Auteurs: David Castellanos‐Robles, Raphaël C. L.‐M. Doineau, Azaam Aziz, Richard Nauber, Song Wu, Silvia Moreno, Konstantina Mitropoulou, Franziska Hebenstreit, Mariana Medina‐Sánchez
Publié dans: Advanced Intelligent Systems, 2024, ISSN 2640-4567
Éditeur: Wiley
DOI: 10.1002/aisy.202400230

DNA data storage in electrospun and melt-electrowritten composite nucleic acid-polymer fibers

Auteurs: Diana Soukarie, Lluis Nocete, Alexander M. Bittner, Ibon Santiago
Publié dans: Materials Today Bio, Numéro 24, 2025, ISSN 2590-0064
Éditeur: Elsevier BV
DOI: 10.1016/J.MTBIO.2023.100900

Factors influencing initial bacterial adhesion to antifouling surfaces studied by single-cell force spectroscopy

Auteurs: Tal Duanis-Assaf, Meital Reches
Publié dans: iScience, Numéro 27, 2024, ISSN 2589-0042
Éditeur: Elsevier BV
DOI: 10.1016/j.isci.2024.108803

Plasma-Treated Poly(Lactic Acid): Deciphering the Structure of a Versatile Engineering Material

Auteurs: Adrián Fontana-Escartín, Nicolas Simon, Oscar Bertran, Alessandro Contini, Juan Torras, Carlos Alemán
Publié dans: ACS Omega, Numéro 10, 2026, ISSN 2470-1343
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/ACSOMEGA.5C08696

New platinum derivatives selectively cause double-strand DNA breaks and death in naïve and cisplatin-resistant cholangiocarcinomas

Auteurs: Irene Olaizola, Mikel Odriozola-Gimeno, Paula Olaizola, Francisco J. Caballero-Camino, Noelia Pastor-Toyos, Mireia Tena-Garitaonaindia, Ainhoa Lapitz, Beatriz Val, Amanda R. Guimaraes, Maitane Asensio, Maider Huici-Izagirre, Colin Rae, David de Sancho, Xabier Lopez, Pedro M. Rodrigues, Elisa Herraez, Oscar Briz, Laura Izquierdo-Sanchez, Aitziber Eleta-Lopez, Alexander M. Bittner, Ana Martinez-Amesti, Teresa Miranda, Sumera I. Ilyas, Chiara Braconi, Maria J. Perugorria, Luis Bujanda, Iván Rivilla, Jose J.G. Marin, Fernando P. Cossío, Jesus M. Banales
Publié dans: Journal of Hepatology, Numéro 83, 2025, ISSN 0168-8278
Éditeur: Elsevier BV
DOI: 10.1016/J.JHEP.2025.04.034

Stereochemical Behavior of Pyrrolo-Pyrazole Peptidomimetics Promoting Phase-Selective Supramolecular Organogels

Auteurs: Enrica Chiesa, Francesco Anastasi, Francesca Clerici, Edoardo Mario Lumina, Ida Genta, Sara Pellegrino, Maria Luisa Gelmi
Publié dans: Gels, Numéro 10, 2024, ISSN 2310-2861
Éditeur: MDPI AG
DOI: 10.3390/gels10040263

Accelerated Molecular Dynamics for Peptide Folding: Benchmarking Different Combinations of Force Fields and Explicit Solvent Models

Auteurs: Crescenzo Coppa, Andrea Bazzoli, Maral Barkhordari, and Alessandro Contini
Publié dans: Journal of Chemical Information and Modeling, 2023, ISSN 1549-9596
Éditeur: ACS publication
DOI: 10.1021/acs.jcim.3c00138

The tubular cavity of tobacco mosaic virus shields mechanical stress and regulates disassembly

Auteurs: A. Díez-Martínez, P. Ibáñez-Freire, R. Delgado-Buscalioni, D. Reguera, A.M. Bittner, P.J. de Pablo
Publié dans: Acta Biomaterialia, Numéro 198, 2025, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/J.ACTBIO.2025.04.012

Smart Electrospun Nanofibers from Short Peptidomimetics Based on Pyrrolo-pyrazole Scaffold

Auteurs: Enrica Chiesa, Francesca Clerici, Raffaella Bucci, Francesco Anastasi, Matteo Bottiglieri, Maddalena Patrini, Ida Genta, Alexander M. Bittner, M. Luisa Gelmi
Publié dans: Biomacromolecules, Numéro 25, 2024, ISSN 1525-7797
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/acs.biomac.3c01310

Self-assembled peptide-based nanofibers for cardiovascular tissue regeneration

Auteurs: Dhriti Shenoy, Sowmya Chivukula, Nursu Erdogan, Enrica Chiesa, Sara Pellegrino, Meital Reches, Ida Genta
Publié dans: Journal of Materials Chemistry B, ISSN 2050-750X
Éditeur: Roial Society of Chemistry
DOI: 10.1039/D4TB01235F

Area‐Selective Silicidation: Patterning Metal Silicides from the Bottom Up

Auteurs: Gabriele Botta, Konstantina Mitropoulou, Evgenii Modin, Manuel Suárez‐Rodríguez, Andrey Chuvilin, Alexander Bittner, Mato Knez
Publié dans: Small Structures, Numéro 6, 2025, ISSN 2688-4062
Éditeur: Wiley
DOI: 10.1002/SSTR.202500282