Functional Nano-Scaffolds for Regenerative Medicine

Informazioni relative al progetto

NANOREMEDI

ID dell’accordo di sovvenzione: 101072645

DOI

10.3030/101072645

Data della firma CE 6 Luglio 2022

Data di avvio 1 Settembre 2022

Data di completamento 31 Agosto 2026

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 3 413 325,60

Coordinato da

UNIVERSITA DEGLI STUDI DI MILANO
Italy

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (1)

Consortium web-site creation and scientific blog

Web site/flyer/broshure prepared

Data Management Plan (1)

Data Management plan submitted

2 Management plans prepared at months 13/45All Beneficiaries involved

Documents, reports (1)

Recruitment advertising publication

Recruitment advertising publication in months 1-3All beneficiaries involvedAdvertisements on EURAXESS; APRE national portals;FindAPhD; Academic Positions and all Beneficiaries web-sites

Pubblicazioni

Conference proceedings (57)

Characterization of complex electrospun matrices through hyperspectral Raman imaging

Autori: Matteo Bottiglieri, Mohammad Amini, Maria L. Gelmi, Alexander M. Bittner
DOI: 10.5281/ZENODO.14856845

Peptide-based nanomaterials for tissue regeneration

Autori: Nursu Erdogan
Editore: zenodo
DOI: 10.5281/ZENODO.18497103

Insights into Non-Natural Peptide Aggregation in Biocompatible Materials: A Classical and Accelerated Molecular Dynamics Study

Autori: Ahmed Saeed, Alessandro Contini, Carlos Enrique Alemàn
DOI: 10.5281/ZENODO.16315905

Bioinspired Peptide-Polymer Coatings for Biomedical Applications

Autori: Nallathambi, Abinaya; GENTA, IDA; Reches, Meital
Pubblicato in: 2025
DOI: 10.5281/ZENODO.15480118

Synthesis of tetraphenylethene L-phenylalanine derivatives and their application in aggregation induced fluorescent peptide materials Creators

Autori: A. I. Antoniou, M. Pesenti, D.S. Shenoy, S. Crespi, M. Penconi, A. Bossi, S. Pellegrino
DOI: 10.5281/ZENODO.14855585

Structural characterization of pure peptide electrospun fibers

Autori: Konstantina Mitropoulou, Meital Reches, Alexander M. Bittne
Editore: zenodo
DOI: 10.5281/ZENODO.14824623

Self-Assembling Lipopeptide Hydrogels as Functional Scaffolds for Tissue Regeneration

Autori: Dhriti Shenoy, Michela Pesenti, Kaliroi Peqini, Emeline Perrier-Groult , Cécile Echalier, Gilles Subra, Sara Pellegrino
Editore: zenodo
DOI: 10.5281/ZENODO.17831143

MANUFACTURING OF SMALL DIAMETER VASCULAR GRAFTS FOR REGENERATIVE PURPOSES

Autori: Erdogan Nursu; Shenoy Santosh Dhriti; Chiesa Enrica; Bittner Alexander; Pellegrino Sara; Genta Ida
DOI: 10.5281/ZENODO.18496808

Synthesis of peptidomimetics using Diaryl-beta-Amino acids for the preparation of smart materials

Autori: Dulce A. Quintana - Romero , Raff a ella Bucci , Merve Gul, Maria M. Pérez - Madrigal, Carlos Al emán, M . Luisa Gelmi
Editore: zenodo
DOI: 10.5281/ZENODO.14853154

Electrospinning of short peptides and characterization through Hyperspectral Raman spectroscopy

Autori: Matteo Bottiglieri, Konstantina Mitropoulou, Maria L. Gelmi and Alexander M. Bittner
DOI: 10.5281/ZENODO.14856710

Develop and Apply Suitable Methods to Perform Molecular Modelling and Perform Conformational Searches and In-Silico Aggregation Studies

Autori: Saeed Ahmed, Alessandro Contini, Carlos Enrique Aleman
DOI: 10.5281/ZENODO.16323992

Playing with Non-Coded Amino Acids to develop Bioinspired Molecular Architectures

Autori: Bucci, Raffaella, Maria Luisa Gelmi, Sara Pellegrino
Editore: zenodo
DOI: 10.5281/ZENODO.14851650

Bioinspired Peptide-Polymer Coatings for Antifouling and Biomedical Applications

Autori: Abinaya Nallathambi; Ida Genta; Meital Reches
DOI: 10.5281/ZENODO.15480118

Self-assembling lipopeptide hydrogels: Bioactive scaffolds for osteochondral tissue regeneration

Autori: Dhriti Shenoy, Michela Pesenti, Kaliroi Peqini, Emeline Perrier-Groult, Cécile Echalier, Gilles Subra, Sara Pellegrino
Editore: zenodo
DOI: 10.5281/ZENODO.18485091

Influnce of drug-polymer interactions on release kinetics of PLGA and PLAPEG Nanoparticles

Autori: Merve Gul, Ida Genta, Maria M. Perez Madrigal, Carlos Aleman, Enrica Chiesa
DOI: 10.5281/ZENODO.16083265

"Synthesis of a peptidomimetics library for the stabilization of supermagnetic nanoparticles for the transdermal delivery. ""Noncanonical amino acids (ncAAs): Tools for Biological and Biophysical Investigations"

Autori: Giulia Servalli, Dulce A. Quintana-Romero, Tommaso Gandini, Raffaella Bucci, Maria Luisa Gelmi
DOI: 10.5281/ZENODO.14853251

Bioengineering of lipopeptides for therapeutic applications

Autori: Dhriti Shenoy, Michela Pesenti, Kaliroi Peqini, Nicolas Simon, Stefania Crespi, Cécile Echalier, Gilles Subra, Sara Pellegrino
DOI: 10.5281/ZENODO.16090099

Self-assembledpeptide-based coating for biomedical applications

Autori: Sowmya Chivukula, Enrica Chiesa, Ida Genta, Meital Reches
Pubblicato in: 2025
DOI: 10.5281/ZENODO.16338936

Pyrrole-Pyrazole Peptidomimetics: From Cycloaddition to Smart Nanomaterials

Autori: M. Bottiglieri, M. L. Gelmi, A. M. Bittner
DOI: 10.5281/ZENODO.15854451

Synthesis of peptidomimetics using Diaryl-β-amino acids for the preparation of smart materials

Autori: Dulce A. Quintana-Romero, R. Bucci, M.L. Gelmi
DOI: 10.5281/ZENODO.14853190

Diving into the blue: Synthetic methodologies toward aggregation induced fluorescent peptide materials

Autori: A.I. Antoniou, M . Pesenti, M. Penconi, D .S. Shenoy, S . Crespi , A . Bossi, S. Pellegrino
Editore: zenodo
DOI: 10.5281/ZENODO.14855564

Electrochemical response of α/β-peptides: Influence of the peptide length, stereochemistry and self-assembly on the performance of peptide-based electrochemical sensors

Autori: Dulce A. Quintana-Romero, Merve Gul, Adrián Fontana-Escartín, M. Luisa Gelmi, Maria M. Pérez-Madrigal, Raffaella Bucci, Carlos Alemán
Pubblicato in: 2026
Editore: zenodo
DOI: 10.5281/ZENODO.18607912

Influnce of drug-polymer interactions on release kinetics of PLGA and PLAPEG Nanoparticles

Autori: Gul, Merve; GENTA, IDA; Perez Madrigal, Maria M.; Aleman, Carlos; CHIESA, ENRICA
Pubblicato in: 2025
DOI: 10.5281/ZENODO.16083265

Silylated peptides as building blocks for material synthesis using sol-gel polymerization and self-assembly

Autori: Mehmet B. Karakaplan, Vinay S. Tiwari, Omer Agazani, Cécile Echalier, Gilles Subra, Meital Reches
DOI: 10.5281/ZENODO.16316211

PEPTIDE-DECORATED ELECTROSPUN SCAFFOLDS AS VASCULAR GRAFT

Autori: Erdogan Nursu; Shenoy Santosh Dhriti; Chiesa Enrica; Bittner Alexander; Pellegrino Sara; Genta Ida
DOI: 10.5281/ZENODO.15911140

Peptide Electrospinning with a Biocompatible Polymer for Biomedical Applications

Autori: Nallathambi, Abinaya; Genta Ida, Reches Meital
Editore: zenodo
DOI: 10.5281/ZENODO.12697491

Investigation of electrochemical response of α/β-peptides: Influence of the peptide length, stereochemistry and self-assembly on the performance of peptide-based electrochemical sensors

Autori: Merve Gul, Dulce A. Quintana-Romero, Adrián Fontana- Escartín, Maria Luisa Gelmi, Maria M. Pérez-Madrigal, Enrica Chiesa, Raffaella Bucci , Carlos Alemán
DOI: 10.5281/ZENODO.16087215

ESEM and AFM structural characterization of short peptide electrospun fibers

Autori: Mitropoulou, Konstantina
DOI: 10.5281/ZENODO.14809558

Late-stage peptide functionalization in the development of aggregation induced emissive smart materials

Autori: M. Pesenti, A.I. Antoniou, D.S. Shenoy, M. Penconi, S. Crespi, A. Bossi, S. Pellegrino
Editore: zenodo
DOI: 10.5281/ZENODO.14855549

Cell - laden scaffolds for osteochondral repai

Autori: Lauren Roberts, Cécile Echalier , Emeline P errier - Groult , Danièle Nöel, Sara Pellegrino, Gilles Subra
Editore: zenodo
DOI: 10.5281/ZENODO.10687294

Manufacturing of composite electrospun VGs for regenerative purposes

Autori: Nursu ERDOĞAN, Ida GENTA, Enrica CHIESA, Alexander BITTNER
DOI: 10.5281/ZENODO.16319745

Synthesis and applications of TPE-based unnatural amino acids characterized by aggregation induced emission. Creators

Autori: M. Pesenti, A.I. Antoniou, D.S. Shenoy, M. Penconi , S. Crespi , A. Bossi, S. Pellegrino
Editore: zenodo
DOI: 10.5281/ZENODO.14855492

ENHANCED SAMPLING METHODS FOR PEPTIDE CONFORMATIONAL ANALYSIS: STRENGTHS, LIMITATIONS, AND APPLICATIONS

Autori: Crescenzo Coppa, Ahmed Saeed, Alessandro Contini
Editore: zenodo

Fabrication of off-the-shelf biodegradable small-caliber Vascular Graftwith improved microbiological and regenerative features

Autori: ABINAYA NALLATHAMBI
Editore: zenodo
DOI: 10.5281/ZENODO.16412716

Sol-gel: a bioorthogonal chemistry for customized biomimetic matrices

Autori: ECHALIER, CECILE, SUBRA, Gilles
Pubblicato in: 2026
Editore: zenodo
DOI: 10.5281/ZENODO.18484646

Smart Functionalization of Pyrrole-Pyrazole Peptidomimetics for Tailored Nanomaterials

Autori: Bottiglieri, Matteo
DOI: 10.5281/ZENODO.14849061

Design and applications of smart nanocarriers to achieve controlled release of antimicrobial agents for regenerative medicine.

Autori: Merve Gul
DOI: 10.5281/ZENODO.16363968

Antifouling Polyurethane Vascular Grafts to Prevent Implant Failure

Autori: Nallathambi, Abinaya, Reches, Meital GENTA, IDA, CHIESA, ENRICA
DOI: 10.5281/ZENODO.14509444

MSC-laden Scaffolds for Osteochondral Repair

Autori: Roberts, L.
DOI: 10.5281/ZENODO.16360812

Insights into Non-Natural Peptide Aggregation in Biocompatible Materials: A Classical and Accelerated Molecular Dynamics Study

Autori: Ahmed, Saeed
Pubblicato in: 2025
DOI: 10.5281/ZENODO.16315905

Self-assembled bifunctional peptide-based coating for biomedical applications

Autori: Sowmya Chivukula, Enrica Chiesa, Ida Genta, Meital Reches
Pubblicato in: 2025
Editore: zenodo
DOI: 10.5281/ZENODO.16337677

Silylated Biopolymer-based Hydrogels for Osteochondral Repair

Autori: Roberts, Lauren
Editore: zenodo
DOI: 10.5281/ZENODO.14853018

Pure peptide electrospun fibres: synthesis, analysis, dissolution

Autori: Konstantina Mitropoulou, Meital Reches, Alexander M. Bittner
DOI: 10.5281/ZENODO.13773974

Designing self-assembling lipopeptide for tissue regeneration

Autori: Dhriti Shenoy, Lauren Roberts, Michela Pesenti, Kaliroi Peqini, Stefania Crespi, Cécile Echalier, Gilles Subra, Sara Pellegrino
Pubblicato in: Proceedings of the 37th European Peptide Symposium, 2024
Editore: The European Peptide Society
DOI: 10.17952/37EPS.2024.P2212

From hybrid peptides to structured bioorganic-inorganic materials

Autori: Qassem, Ali
DOI: 10.5281/ZENODO.14846404

ESEM and AFM structural characerization of short peptide electrospun fibers

Autori: Mitropoulou, Konstantina
DOI: 10.5281/ZENODO.14823922

Self-Assembling Lipopeptide Hydrogels: Building Bioactive Scaffolds for Next- Gen Tissue Regeneration

Autori: Dhriti Shenoy, Michela Pesenti, Kaliroi Peqini, Emeline Perrier-Groult, Cécile Echalier, Gilles Subra, Sara Pellegrino
DOI: 10.5281/ZENODO.16317090

A PRELIMINARY STUDY OF PEPTIDE DECORATED ELECTROSPUN SCAFFOLDS AS VASCULAR GRAFTS

Autori: Erdogan Nursu, Shenoy Santosh Dhriti, Chiesa Enrica, Bittner Alexander, Pellegrino Sara, Genta Ida
Editore: zenodo
DOI: 10.5281/ZENODO.11477050

Synthesis of peptidomimetics using Diaryl-β amino acids for the preparation of smart materials

Autori: Dulce A. Quintana - Romero , Raffaella Bucci, Merve Gul, Maria M. Pérez - Madrigal, Carlos Alemán, M . Luisa Gelmi
DOI: 10.5281/ZENODO.14853207

Elastin-Like Polypeptide Mimetics: from synthesis to material characterization

Autori: Bottiglieri, Matteo
DOI: 10.5281/ZENODO.14848988

Insights into Non-Natural Peptide Aggregation in Biocompatible Materials: A Classical and Accelerated Molecular Dynamics Study

Autori: Ahmed, Saeed
Pubblicato in: 2025
DOI: 10.5281/ZENODO.16315905

Self-assembled bifunctional peptide-based coating for biomedical applications

Autori: Sowmya Chivukula, Enrica Chiesa, Ida Genta, Meital Reches
Pubblicato in: 2025
DOI: 10.5281/ZENODO.16338529

Ultrathin water layers on viruses

Autori: A.M. Bittner, M.A. Iriarte - Alonso , J.H. Melillo , S . Cerveny , S. Chiantia
Editore: zenodo
DOI: 10.5281/ZENODO.148573202

pH-responsive self-assembling IKVAV-derived peptides: in silico and in vitro analysis

Autori: Dhriti S. Shenoy, Allegra Ascagni,Michela Pesenti, Antonia I. Antoniou, Alfonso Gautieri, Sara Pellegrino
Editore: zenodo
DOI: 10.5281/ZENODO.10797615

Designing self-assembling bioactive lipopeptide

Autori: Shenoy, D. S., Pellegrino, S., Peqini, K., Pesenti, M., Simon, N., ECHALIER, C., & SUBRA, G.
DOI: 10.5281/ZENODO.15747367

Electrochemical response of α/β-peptides: Influence of the peptide length, stereochemistry and self-assembly on the performance of peptide-based electrochemical sensors

Autori: Dulce A. Quintana-Romero, Merve Gul, Adrián Fontana-Escartín, M. Luisa Gelmi, Maria M. Pérez-Madrigal, Raffaella Bucci, Carlos Alemán
DOI: 10.5281/ZENODO.16267859

Cell-laden Scaffolds for Osteochondral Repair

Autori: Lauren Roberts, Cécile Echalier , Emeline P errier - Groult , Danièle Nöel, Sara Pellegrino, Gilles Subra
DOI: 10.5281/ZENODO.10691699

Peer reviewed articles (14)

From Dielectric to Electro-Responsive Thermoplastics: An Approach Based on Electro-Thermal Re-orientation and Charged Gas Activation

Autori: Gul, Merve; Fontana-Escartin, Adrián; Arnau, Marc; Sans, Jordi; Lanzalaco, Sonia,; Armelin, Elaine; Chiesa, Enrica; Genta, Ida; Perez-Madrigal, Maria; Alemán, Carlos
Pubblicato in: ACS Applied Polymer Materials, ISSN 2637-6105
Editore: ACS
DOI: 10.1021/ACSAPM.4C02610

Aggregation-Induced Enhanced Emission of Tetraphenylethene-phenylalanine Hybrids: Synthesis and Characterization

Autori: Antonia I. Antoniou, Michela Pesenti, Stefania Crespi, Dhriti S. Shenoy, Marta Penconi, Alberto Bossi, Sara Pellegrino
Pubblicato in: The Journal of Organic Chemistry, Numero 89, 2024, ISSN 0022-3263
Editore: American Chemical Society (ACS)
DOI: 10.1021/acs.joc.3c02969

Silylated peptides as building blocks for material synthesis using sol–gel polymerization

Autori: Mehmet B. Karakaplan, Vinay S. Tiwari, Omer Agazani, Cécile Echalier, Gilles Subra, Meital Reches
Pubblicato in: Faraday Discussions, 2025, ISSN 1359-6640
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/D5FD00014A

Multimodal Imaging, Drug Delivery, and On‐Board Triggered Degradation in Soft Capsule Rolling Microrobots

Autori: David Castellanos‐Robles, Raphaël C. L.‐M. Doineau, Azaam Aziz, Richard Nauber, Song Wu, Silvia Moreno, Konstantina Mitropoulou, Franziska Hebenstreit, Mariana Medina‐Sánchez
Pubblicato in: Advanced Intelligent Systems, 2024, ISSN 2640-4567
Editore: Wiley
DOI: 10.1002/aisy.202400230

DNA data storage in electrospun and melt-electrowritten composite nucleic acid-polymer fibers

Autori: Diana Soukarie, Lluis Nocete, Alexander M. Bittner, Ibon Santiago
Pubblicato in: Materials Today Bio, Numero 24, 2025, ISSN 2590-0064
Editore: Elsevier BV
DOI: 10.1016/J.MTBIO.2023.100900

Factors influencing initial bacterial adhesion to antifouling surfaces studied by single-cell force spectroscopy

Autori: Tal Duanis-Assaf, Meital Reches
Pubblicato in: iScience, Numero 27, 2024, ISSN 2589-0042
Editore: Elsevier BV
DOI: 10.1016/j.isci.2024.108803

Plasma-Treated Poly(Lactic Acid): Deciphering the Structure of a Versatile Engineering Material

Autori: Adrián Fontana-Escartín, Nicolas Simon, Oscar Bertran, Alessandro Contini, Juan Torras, Carlos Alemán
Pubblicato in: ACS Omega, Numero 10, 2026, ISSN 2470-1343
Editore: American Chemical Society (ACS)
DOI: 10.1021/ACSOMEGA.5C08696

New platinum derivatives selectively cause double-strand DNA breaks and death in naïve and cisplatin-resistant cholangiocarcinomas

Autori: Irene Olaizola, Mikel Odriozola-Gimeno, Paula Olaizola, Francisco J. Caballero-Camino, Noelia Pastor-Toyos, Mireia Tena-Garitaonaindia, Ainhoa Lapitz, Beatriz Val, Amanda R. Guimaraes, Maitane Asensio, Maider Huici-Izagirre, Colin Rae, David de Sancho, Xabier Lopez, Pedro M. Rodrigues, Elisa Herraez, Oscar Briz, Laura Izquierdo-Sanchez, Aitziber Eleta-Lopez, Alexander M. Bittner, Ana Martinez-Amesti, Teresa Miranda, Sumera I. Ilyas, Chiara Braconi, Maria J. Perugorria, Luis Bujanda, Iván Rivilla, Jose J.G. Marin, Fernando P. Cossío, Jesus M. Banales
Pubblicato in: Journal of Hepatology, Numero 83, 2025, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/J.JHEP.2025.04.034

Stereochemical Behavior of Pyrrolo-Pyrazole Peptidomimetics Promoting Phase-Selective Supramolecular Organogels

Autori: Enrica Chiesa, Francesco Anastasi, Francesca Clerici, Edoardo Mario Lumina, Ida Genta, Sara Pellegrino, Maria Luisa Gelmi
Pubblicato in: Gels, Numero 10, 2024, ISSN 2310-2861
Editore: MDPI AG
DOI: 10.3390/gels10040263

Accelerated Molecular Dynamics for Peptide Folding: Benchmarking Different Combinations of Force Fields and Explicit Solvent Models

Autori: Crescenzo Coppa, Andrea Bazzoli, Maral Barkhordari, and Alessandro Contini
Pubblicato in: Journal of Chemical Information and Modeling, 2023, ISSN 1549-9596
Editore: ACS publication
DOI: 10.1021/acs.jcim.3c00138

The tubular cavity of tobacco mosaic virus shields mechanical stress and regulates disassembly

Autori: A. Díez-Martínez, P. Ibáñez-Freire, R. Delgado-Buscalioni, D. Reguera, A.M. Bittner, P.J. de Pablo
Pubblicato in: Acta Biomaterialia, Numero 198, 2025, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/J.ACTBIO.2025.04.012

Smart Electrospun Nanofibers from Short Peptidomimetics Based on Pyrrolo-pyrazole Scaffold

Autori: Enrica Chiesa, Francesca Clerici, Raffaella Bucci, Francesco Anastasi, Matteo Bottiglieri, Maddalena Patrini, Ida Genta, Alexander M. Bittner, M. Luisa Gelmi
Pubblicato in: Biomacromolecules, Numero 25, 2024, ISSN 1525-7797
Editore: American Chemical Society (ACS)
DOI: 10.1021/acs.biomac.3c01310

Self-assembled peptide-based nanofibers for cardiovascular tissue regeneration

Autori: Dhriti Shenoy, Sowmya Chivukula, Nursu Erdogan, Enrica Chiesa, Sara Pellegrino, Meital Reches, Ida Genta
Pubblicato in: Journal of Materials Chemistry B, ISSN 2050-750X
Editore: Roial Society of Chemistry
DOI: 10.1039/D4TB01235F

Area‐Selective Silicidation: Patterning Metal Silicides from the Bottom Up

Autori: Gabriele Botta, Konstantina Mitropoulou, Evgenii Modin, Manuel Suárez‐Rodríguez, Andrey Chuvilin, Alexander Bittner, Mato Knez
Pubblicato in: Small Structures, Numero 6, 2025, ISSN 2688-4062
Editore: Wiley
DOI: 10.1002/SSTR.202500282