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Decoding novel reaction chemistries in biocatalysis – Training Europe’s next visionaries for a sustainable future

Project description

Training on enzyme-related technologies

The industrial biotechnology sector heavily relies on enzyme catalysis to enhance the sustainability of chemical processes and product synthesis. However, the current processes for enzyme synthesis are expensive and harmful to the environment. The EU-funded BiodeCCodiNNg project will revolutionise the chemical and pharmaceutical industries by training 10 promising doctoral candidates on enzyme-related technologies. It will develop an innovative solution for enzyme synthesis. With the assistance of industrial partners, stakeholders, European academic institutions and experts, the project will fill the technological gaps and explore the massive benefits of improved enzyme synthesis.

Objective

Enzyme catalysis is an essential technology at the heart of industrial biotechnology, expected to foster the EU economic growth and industry leadership, while effectively addressing social, environmental, and economic needs. It improves the sustainability of chemical processes and gives rise to new reactivities for multi-functionalized product building. Traditional chemical methods for their synthesis are typically realized by costly and environmentally unfriendly processes. Expanding the toolbox of available biocatalysts enabling novel reactions not yet accessible with the existing enzymes is a formidable challenge, but will open exciting new avenues for applications in the chemical and pharmaceutical industries. The BIODECCODINNG consortium will address this challenge by decoding novel reaction chemistries from the largely underexploited family of N-N bond forming enzymes, while addressing challenging reactions performed by C-C bond forming enzymes that are currently not accessible.
The main goal of the BIODECCODINNG DN is to train and educate Europe’s next 10 visionaries for a sustainable future on cutting-edge enzyme technology centered around N-N and C-C bond formations, and to tackle technology gaps, practical challenges, as well as to exploit synthetic opportunities with a huge innovation potential. The network is established by world-leading experts from European academic institutions and industrial partners that will together implement the training agenda. This setting provides strong interdisciplinary co-supervision and intersectoral exposure in secondments to the doctoral candidates, and bridges intersectoral and multidisciplinary boundaries across training in leading-edge drug discovery, enzyme catalysis and process development. BIODECCODINNG will therewith prepare the next generation of researchers for the implementation of sustainable enzymatic processes comprising C-C- and N-N bond forming enzymes in the European Biotech sector.

Coordinator

RIJKSUNIVERSITEIT GRONINGEN
Net EU contribution
€ 823 111,20
Address
Broerstraat 5
9712CP Groningen
Netherlands

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Region
Noord-Nederland Groningen Overig Groningen
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data

Participants (6)

Partners (13)