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Decoding novel reaction chemistries in biocatalysis – Training Europe’s next visionaries for a sustainable future

Objective

Enzyme catalysis is an essential technology at the heart of industrial biotechnology, expected to foster the EU economic growth and industry leadership, while effectively addressing social, environmental, and economic needs. It improves the sustainability of chemical processes and gives rise to new reactivities for multi-functionalized product building. Traditional chemical methods for their synthesis are typically realized by costly and environmentally unfriendly processes. Expanding the toolbox of available biocatalysts enabling novel reactions not yet accessible with the existing enzymes is a formidable challenge, but will open exciting new avenues for applications in the chemical and pharmaceutical industries. The BIODECCODINNG consortium will address this challenge by decoding novel reaction chemistries from the largely underexploited family of N-N bond forming enzymes, while addressing challenging reactions performed by C-C bond forming enzymes that are currently not accessible.
The main goal of the BIODECCODINNG DN is to train and educate Europe’s next 10 visionaries for a sustainable future on cutting-edge enzyme technology centered around N-N and C-C bond formations, and to tackle technology gaps, practical challenges, as well as to exploit synthetic opportunities with a huge innovation potential. The network is established by world-leading experts from European academic institutions and industrial partners that will together implement the training agenda. This setting provides strong interdisciplinary co-supervision and intersectoral exposure in secondments to the doctoral candidates, and bridges intersectoral and multidisciplinary boundaries across training in leading-edge drug discovery, enzyme catalysis and process development. BIODECCODINNG will therewith prepare the next generation of researchers for the implementation of sustainable enzymatic processes comprising C-C- and N-N bond forming enzymes in the European Biotech sector.

Funding Scheme

MSCA-DN - MSCA-DN

Coordinator

RIJKSUNIVERSITEIT GRONINGEN
Net EU contribution
€ 823 111,20
Address
Broerstraat 5
9712CP Groningen
Netherlands

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Region
Noord-Nederland Groningen Overig Groningen
Activity type
Higher or Secondary Education Establishments
Other funding
No data

Participants (6)

RUHR-UNIVERSITAET BOCHUM
Germany
Net EU contribution
€ 260 539,20
Address
Universitaetsstrasse 150
44801 Bochum

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Region
Nordrhein-Westfalen Arnsberg Bochum, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
No data
SVEUCILISTE U ZAGREBU FAKULTET KEMIJSKOG INZENJERSTVA I TEHNOLOGIJE
Croatia
Net EU contribution
€ 232 632,00
Address
Marulicev Trg 19
10000 Zagreb

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Region
Hrvatska Grad Zagreb Grad Zagreb
Activity type
Higher or Secondary Education Establishments
Other funding
No data
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
Net EU contribution
€ 251 971,20
Address
Calle Serrano 117
28006 Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
Other funding
No data
FORSCHUNGSZENTRUM JULICH GMBH
Germany
Net EU contribution
€ 260 539,20
Address
Wilhelm Johnen Strasse
52428 Julich

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Region
Nordrhein-Westfalen Köln Düren
Activity type
Research Organisations
Other funding
No data
UNIVERSITAET GRAZ
Austria
Net EU contribution
€ 540 662,40
Address
Universitatsplatz 3
8010 Graz

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Region
Südösterreich Steiermark Graz
Activity type
Higher or Secondary Education Establishments
Other funding
No data
GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS
Germany
Net EU contribution
€ 260 539,20
Address
Wilhelmsplatz 1
37073 Gottingen

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Region
Niedersachsen Braunschweig Göttingen
Activity type
Higher or Secondary Education Establishments
Other funding
No data

Partners (13)

UNIVERSITAT DE BARCELONA
Spain
Net EU contribution
€ 0,00
Address
Gran Via De Les Corts Catalanes 585
08007 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Higher or Secondary Education Establishments
Other funding
No data
Innophore GmbH
Austria
Net EU contribution
€ 0,00
Address
Am Eisernen Tor 3
8010 Graz

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Südösterreich Steiermark Graz
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
ENZYMICALS AG
Germany
Net EU contribution
€ 0,00
Address
Walther-rathenau-strasse 49a
17489 Greifswald

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Mecklenburg-Vorpommern Mecklenburg-Vorpommern Vorpommern-Greifswald
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
CHIRALVISION BV
Netherlands
Net EU contribution
€ 0,00
Address
Hoog-harnasch 44
2635 DL Den Hoorn

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Zuid-Holland Delft en Westland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
ASTRAZENECA AB
Sweden
Net EU contribution
€ 0,00
Address
Vastra Maelarhamnen
151 85 Sodertaelje

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
PROZOMIX LIMITED
United Kingdom
Net EU contribution
€ 0,00
Address
Station Court 3
NE49 9HN Haltwhistle

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
North East (England) Northumberland and Tyne and Wear Northumberland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
BASF SE
Germany
Net EU contribution
€ 0,00
Address
Carl Bosch Strasse 38
67063 Ludwigshafen Am Rhein

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Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
ZYMVOL BIOMODELING SL
Spain
Net EU contribution
€ 0,00
Address
Calle Roc Boronat 117 Planta 2 Modulo 6
08018 Barcelona

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Este Cataluña Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
SPINCHEM AB
Sweden
Net EU contribution
€ 0,00
Address
Tvistevagen 48c
90736 Umea

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Norra Sverige Övre Norrland Västerbottens län
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
F. HOFFMANN-LA ROCHE AG
Switzerland
Net EU contribution
€ 0,00
Address
Grenzacherstrasse 124
4070 Basel

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Region
Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
PUROLITE LTD
United Kingdom
Net EU contribution
€ 0,00
Address
Unit D, Llantrisant Business Park
CF728LF Llantrisant

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Region
Wales West Wales and The Valleys Central Valleys
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
CLUSTER INDUSTRIELLE BIOTECHNOLOGIE EV
Germany
Net EU contribution
€ 0,00
Address
Volklinger Strasse 4
40219 Dusseldorf

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nordrhein-Westfalen Düsseldorf Düsseldorf, Kreisfreie Stadt
Activity type
Other
Other funding
No data
RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN
Germany
Net EU contribution
€ 0,00
Address
Templergraben 55
52062 Aachen

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Region
Nordrhein-Westfalen Köln Städteregion Aachen
Activity type
Higher or Secondary Education Establishments
Other funding
No data