Targeting RNA as an approach for treating retinal disease

Project Information

RETORNA

Grant agreement ID: 101073316

DOI

10.3030/101073316

EC signature date 6 July 2022

Start date 1 February 2023

End date 31 January 2027

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 568 425,56

Coordinated by

FUNDACION UNIVERSIDAD CATOLICA DE VALENCIA SAN VICENTE MARTIR
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Other (1)

Advertising vacancies

DCs vacancies will be advertise in many specialized websites, including EUROAXESS

Websites, patent fillings, videos etc. (1)

RETORNA website available

A website for the project will be publicly available.

Documents, reports (1)

Analysis of retinal morphology and physiology in CACD patients and Prph2 mouse as a new model of CACD

Visual acuity will be measured by optomotor test (OMT). Retinal function will be measured by electroretinographic recordings (ERG). Retinal structure and its vascularization will be evaluated by optical coherence tomography (OCT) and OCT angiography (OCTA). Retinal morphology will be analyzed by different immunohistochemical stains in a cross-sectional retinal cryosections.

Publications

Other (2)

miR-429 RNA therapy as generic strategy to protect against photoreceptor loss

Author(s): Jan Wijnholds
Published in: Molecular Therapy Nucleic Acids, Issue 36, 2025, ISSN 2162-2531
Publisher: Elsevier BV
DOI: 10.1016/J.OMTN.2025.102477

The Future of Nanomaterials Tackling the Challenge of Delivering Nucleic Acids to the Retina

Author(s): Adams, Friederike; Hurst, Jose; Schnichels, Sven
Published in: Advanced Functional Materials, Issue 35, 2025, ISSN 1616-301X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ADFM.202407173

Peer reviewed articles (7)

Role of Exosomal miR-205-5p Cargo in Angiogenesis and Cell Migration

Author(s): Miriam Martínez-Santos; María Ybarra; María Oltra; María Muriach; Francisco J. Romero; Maria E. Pires; Javier Sancho-Pelluz; Jorge M. Barcia
Published in: International Journal of Molecular Sciences, 2024
Publisher: MDPI
DOI: 10.3390/ijms25020934

miR-205-5p Modulates High Glucose-Induced VEGFA Levels in Diabetic Mice and ARPE-19 Cells

Author(s): María Ybarra, Miriam Martínez-Santos, Maria Oltra, María Muriach, Maria E. Pires, Chiara Ceresoni, Javier Sancho-Pelluz, Jorge M. Barcia
Published in: Antioxidants, Issue 14, 2025, ISSN 2076-3921
Publisher: MDPI AG
DOI: 10.3390/ANTIOX14020218

Role of Exosomal miR-205-5p Cargo in Angiogenesis and Cell Migration

Author(s): Miriam Martínez-Santos, María Ybarra, María Oltra, María Muriach, Francisco J. Romero, Maria E. Pires, Javier Sancho-Pelluz, Jorge M. Barcia
Published in: International Journal of Molecular Sciences, Issue 25, 2024, ISSN 1422-0067
Publisher: MDPI AG
DOI: 10.3390/IJMS25020934

The Future of Nanomaterials Tackling the Challenge of Delivering Nucleic Acids to the Retina

Author(s): Jos Hurst, Friederike Adams, Sven Schnichels
Published in: Advanced Functional Materials, Issue 35, 2025, ISSN 1616-301X
Publisher: Wiley
DOI: 10.1002/adfm.202407173

miR-429 RNA therapy as generic strategy to protect against photoreceptor loss

Author(s): Jan Wijnholds
Published in: Molecular Therapy Nucleic Acids, Issue 36, 2025, ISSN 2162-2531
Publisher: Elsevier BV
DOI: 10.1016/j.omtn.2025.102477

Role of Exosomal miR-205-5p Cargo in Angiogenesis and Cell Migration

Author(s): Miriam Martnez-Santos, Mara Ybarra, Mara Oltra, Mara Muriach, Francisco J. Romero, Maria E. Pires, Javier Sancho-Pelluz, Jorge M. Barcia
Published in: International Journal of Molecular Sciences, Issue 25, 2024, ISSN 1422-0067
Publisher: MDPI AG
DOI: 10.3390/ijms25020934

miR-205-5p Modulates High Glucose-Induced VEGFA Levels in Diabetic Mice and ARPE-19 Cells

Author(s): Mara Ybarra, Miriam Martnez-Santos, Maria Oltra, Mara Muriach, Maria E. Pires, Chiara Ceresoni, Javier Sancho-Pelluz, Jorge M. Barcia
Published in: Antioxidants, Issue 14, 2025, ISSN 2076-3921
Publisher: MDPI AG
DOI: 10.3390/antiox14020218

Conference proceedings (1)

Value in Health

Author(s): C Willmington, A Murphy, A Kirby
Published in: Value in Health, Issue 27, 2024, ISSN 1098-3015
Publisher: Elsevier BV
DOI: 10.1016/J.JVAL.2024.10.665