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human pluripotent stem cell registry - hPSCreg

Project description

Global open-access human stem cell registry

The human pluripotent stem cell registry provides validated information about human embryonic stem cells and other pluripotent stem cells (PSC), including human-induced PSC (hiPSC). The information includes data on ethical provenance and quality, cell line application and clinical studies. The open-access registry is a global resource of PSC with the purpose of maximising cell utility and minimising research as well as ethical and regulatory risks. The main task of the EU-funded hPSCreg project is to maintain and improve centralised registry function for validation and monitoring of ethical and scientific developments. Moreover, it will undertake PSC certification to assure the highest quality and reliability in stem cell research, and encourage inclusion of diverse stakeholders in the communication process on emerging PSC technologies.

Objective

The human pluripotent stem cell registry (hPSCreg) is providing validated information about human embryonic stem cells (ESC) and other human pluripotent stem cells (PSC) such as induced PSC. This information is linked through an unique persistent identifier and it includes data on ethical provenance and scientific quality, cell line application and clinical studies performed with hPSC. The open access Registry acts globally to provide a transparent resource and tool for PSC, to maximize cell utility, reproducibility and benefit and minimize research, ethical and regulatory risks. It validates and certifies the registered cell lines based on the provided documents, data and information, assuring high quality of certified lines. hPSCreg is involved in multiple EU-Projects, international consortia and organizations to provide information, data standards and support dissemination. The main task of hPSCcreg within this project proposal are to maintain and improve its function as a centralized registry of hESC and hiPSC lines allowing for (i) transparent validation and monitoring of the ethical and scientific developments in the field; (ii) transparent data – based certification of PSC to assure and maintain highest quality; (iii) implementing FAIR data standards and a continuously improved data reliability in downstream stem cell research; (iv) supporting academic, industrial and clinical research on PSCs and maximizing their potential; and (v) inclusion of diverse stakeholders in the communication process on emerging PSC - based technologies, including research towards clinical applications.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-CSA - HORIZON Coordination and Support Actions

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Call for proposal

(opens in new window) HORIZON-HLTH-2021-hPSC-09-IBA

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Coordinator

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Net EU contribution
€ 1 499 317,50
Address
HANSASTRASSE 27C
80686 Munchen
Germany
Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Links
Total cost
€ 1 499 317,50