Mechanism, Regulation and Functions of DNA Loop Extrusion by SMC complexes

Project Information

LoopSMC

Grant agreement ID: 101076914

DOI 10.3030/101076914

EC signature date 20 December 2022

Start date 1 April 2023

End date 31 March 2028

Funded under

• European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

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Publications

Peer reviewed articles (4)

Molecular mechanism of condensin I activation by KIF4A

Author(s): Erin E Cutts, Damla Tetiker, Eugene Kim, Luis Aragon
Published in: The EMBO Journal, Issue 44, 2025, ISSN 1460-2075
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S44318-024-00340-W

In vitro dynamics of DNA loop extrusion by structural maintenance of chromosomes complexes

Author(s): Marius Rutkauskas, Eugene Kim
Published in: Current Opinion in Genetics & Development, Issue 90, 2025, ISSN 0959-437X
Publisher: Elsevier BV
DOI: 10.1016/J.GDE.2024.102284

Loop-extruding Smc5/6 organizes transcription-induced positive DNA supercoils

Author(s): Kristian Jeppsson, Biswajit Pradhan, Takashi Sutani, Toyonori Sakata, Miki Umeda Igarashi, Davide Giorgio Berta, Takaharu Kanno, Ryuichiro Nakato, Katsuhiko Shirahige, Eugene Kim, Camilla Bjrkegren
Published in: Molecular Cell, Issue 84, 2024, ISSN 1097-2765
Publisher: Elsevier BV
DOI: 10.1016/j.molcel.2024.01.005

Loop-extrusion-mediated plasmid DNA cleavage by the bacterial SMC Wadjet complex

Author(s): Biswajit Pradhan, Amar Deep, Jessica Knig, Martin D. Baaske, Kevin D. Corbett, Eugene Kim
Published in: Molecular Cell, Issue 85, 2025, ISSN 1097-2765
Publisher: Elsevier BV
DOI: 10.1016/j.molcel.2024.11.002