Description du projet
Faire progresser les recherches en épigénétique
L’épigénétique concerne les modifications de l’expression génétique qui se produisent sans altération de la séquence d’ADN. Ces modifications peuvent être transmises de génération en génération et être influencées par des facteurs environnementaux, notamment des facteurs alimentaires, des produits chimiques et des facteurs de stress lors de la conception ou plus tard au cours de la vie utérine. Le projet EPIBOOST, financé par l’UE, entend renforcer les capacités de recherche des partenaires impliqués dans le domaine de l’épigénétique environnementale. L’étude, axée sur la méthylation de l’ADN en tant que biomarqueur de l’impact environnemental, sera accompagnée d’activités de formation portant sur un large éventail de sujets et de compétences pratiques.
Objectif
The EPIBOOST project joins a widening partner and two internationally-leading partners that will steer a solid capacitation strategy towards tackling the challenges to the recently proposed uptake of epigenomics by Environmental Assessment frameworks. Capacitation activities cover for 5 specific objectives. The 1st is to optimize research protocols, enhancing the practical skills and research profile of the Widening partner for the development of excellent Science in the field of environmental epigenetics. This constitutes the nurturing stage, where we will be twinning (exchanges and training sessions) under an overall philosophy of learning- and advancing-by-doing allowed by a preparatory research project, which will build knowledge on the suitability of DNA methylation signatures as informative biomarkers of environmental contamination and effects. The 2nd objective is focused on the seeding of the talent that will sustain the European critical mass at the best world-class standards in the field, through the organization of several training events (advanced courses, summer schools and short courses in scientific meetings) targeting young EU researchers. The 3rd and 4th objectives regard the absolute need of a capacitated science management and administrative support to effectively grow world-class research in the field; these will be tackled through an immersive training programme focusing key core facilities (ethics & animal housing; sequencing), managers exchange for on-site training, professional training and real-time funding application preparation. The fifth addresses network growing and will be achieved through a systematic strategy for involving international flagship experts in capacitation activities and stakeholders in the project, which will strengthen the Consortium for new research and innovation ventures.
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HORIZON-CSA - HORIZON Coordination and Support ActionsCoordinateur
3810-193 Aveiro
Portugal