Strengthening excellence for advanced osteosarcoma’s predictive models

Livrables

Short Term Staff Exchanges Report (activities and evaluation) - Second Period

Report on the Short Term Staff Exchanges (inwards & outwards) (second period), including insights from the reports produced by the researchers enrolled in the secondments, as well as a report on the experts visits. Deliverable related to Task 4.1.

Manual for Career Development

Booklet gathering the topics, questions, tips and answers raised during mentorship and coaching provided within Task 4.4. Deliverable related to Task 4.4.

Management and Coordination Handbook

Guide with information on the consortium members, committees, project management and coordination procedures, reporting procedures, internal communication policies, templates to be used within the project, and tools to be used to ensure a smooth project implementation. Deliverable related to Task 1.1.

Scaffold for 3D OS model

Report and scientific publications on the activities and results from the design and printing of scaffold for 3D OS model. Deliverable related to Task 3.2.

Communication, dissemination and outreach: plan

Communication, dissemination and outreach plan of the project. Deliverable related to Task 5.1.

Research Management and Administrative Skills – Report on Activities

Deliverable reporting the short staff exchanges: agendas, results, thematic sessions... Deliverable related to Task 2.3.

Strategic Research Agenda and Funding Roadmap - 1

Strategic Research Agenda (SRA) designed based on the competencies of the consortium. It will include also the results of an analysis on the available opportunities for exploitation actions, such as funding programmes. The results of the cooperation actions with S&T entities and the industry will be also included. Deliverable related to Tasks 2.1 and 2.2.

PREDICTOS Diversity illustration: tools and guidelines

Document detailing the tools and providing guidelines to measure the diversity balance and equal access in the project activities. Deliverable related to Task 1.4.

Strategic Research Agenda and Funding Roadmap - 2

Update to D2.1. - Strategic Research Agenda and Funding Roadmap - 1. Deliverable related to Tasks 2.1 and 2.2.

In silico model that mimic tumour microenvironment

Report and scientific publications on the activities and results related to the development of in silico models. Deliverable related to Task 3.4.

Novel biomaterial-deposition module

Report on the activities and results related to the development of a novel biomaterial-deposition module to be integrated in ad-hoc biomanufacturing system. Deliverable related to Task 3.1.

PREDICTOS Diversity illustration: report

Document reporting the diversity dimension of the project activities, including the tools used to measure the diversity balance and equal access in the activities and possible corrective procedures performed. Deliverable related to Task 1.4.

PREDICTOS Progress report

Interim report addressing the progress of the project accomplished: status on objectives, KPI and milestones achievements; scientific and non-scientific accomplishments; activities performed; risk assessment; plan for the next period... Deliverable related to Task 1.1.

Ethics and Data Management Plan - 1

Plan that will define the ethical standards to be followed by the project and detail how data will be managed by the project, in compliance with EU best practices and requirements. It will follow the template available for DMP for HE projects, focusing the first part on data related issues, and the second part on other ethics issues if pertinent. Deliverable related to Task 1.3.

Sustainability and Exploitation Strategy - 1

Sustainability and Exploitation Strategy containing the project plan concerning the results exploitation and sustainability. Deliverable related to Task 5.4.

Quality Assurance and Risk Management Plan

Plan to guarantee the overall quality monitoring process, with a focus on the review process of deliverables, annual reports and milestones completion. It also includes the identification of potential risks and mitigation strategies. It will be kept as a living document and updated over the course of the project whenever significant changes arise. On M13, deep analysis and assessment will be performed to assess the validity of the plan, which shall be updated if necessary. Deliverable related to Task 1.2.

Sustainability and Exploitation Strategy - 2

Strategy updating D5.5, reporting on the activities performed during the project, and addressing dissemination and exploitation measures to be implemented in a period up to 4 years after the end the project. Deliverable related to Task 5.4.

Communication, dissemination and outreach: second period report

Report on the communication, dissemination and outreach activities performed by the project in the second period. Deliverable related to Tasks 5.2 and 5.3.

Communication, dissemination and outreach: first period report and plan update

Report on the communication, dissemination and outreach activities performed by the project in the first period (related to Tasks 5.2 and 5.3), and update to the plan presented in D5.1 (related to Task 5.1).

3D in vitro model that mimic tumour microenvironment

Report and scientific publications on the activities and results related to 3D in vitro studies and mimicking tumour environment. Deliverable related to Task 3.3.

Ethics and Data Management Plan - 2

Update to D1.3 - Ethics and Data Management Plan - 1. Deliverable related to Task 1.3.

3D OS model combined with magnetic stimulation as therapeutic strategy to remove remained cancer cells

Report and scientific publications on the activities and results related to the testing of proof of concept of the predictive defined models (task 3.3 and task 3.4) for novel therapeutic strategy for the elimination of remained cancer cells after OS removal. Deliverable related to Task 3.5.

Workshops and Summer Schools Report (activities and evaluation)

Report on the Thematic Workshops and Summer Schools, including the activities delivered, assessment on the impact reached, provision of recommendations. Deliverable related to Tasks 4.2 and 4.3.

Short Term Staff Exchanges Report (activities and evaluation) - First Period

Report on the Short Term Staff Exchanges (inwards & outwards) (first period), including insights from the reports produced by the researchers enrolled in the secondments, as well as a report on the experts visits. Deliverable related to Task 4.1.

Publications

Magnetic-responsive materials tailored to enhance the cascade of bone regeneration and immune response

Auteurs: Ana Catarina Almeida, Diana Pacheco, Artur Mateus, Monica Montesi, Silvia Panseri, Nuno Alves, Simone Sprio, Tatiana M. Fernandes Patrício
Publié dans: Materials & Design, Numéro 251, 2025, ISSN 0264-1275
Éditeur: Elsevier BV
DOI: 10.1016/J.MATDES.2025.113645

Next-generation osteosarcoma models for precision medicine

Auteurs: Mohamed Saqawa, Miguel Vieira Coelho, Marta Lourenço, Claire Villette, David Barata, Lorenzo Apolloni, Silvia Panseri, A. S. Silva-Barroso, Rafaela Seabra, Diana Pacheco, Nuno Alves, Paula Faria, Bernard Staumont, Liesbet Geris, Carlos Mota, Monica Montesi, Tatiana M. Fernandes Patrício
Publié dans: Communications Biology, Numéro 9, 2026, ISSN 2399-3642
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S42003-026-10650-W

Microalgal therapeutic peptides: From biomass to bone tissue engineering

Auteurs: Diana Pacheco, Tatiana M.F. Patrício, Abílio J.F.N. Sobral, Telma Encarnação
Publié dans: Materials Today Bio, Numéro 37, 2026, ISSN 2590-0064
Éditeur: Elsevier BV
DOI: 10.1016/J.MTBIO.2026.102938

Current Strategies to Produce 3D Electrospun-Based Wound Dressings for Skin Regeneration

Auteurs: Carolina A. M. Ferreira, Marco F. L. Lemos, Ana Colette Maurício, Juliana R. Dias
Publié dans: Polymer Reviews, Numéro 65, 2026, ISSN 1558-3724
Éditeur: Informa UK Limited
DOI: 10.1080/15583724.2025.2524625

Expanding the Potential of Self-Assembled Silk Fibroin as Aerogel Particles for Tissue Regeneration

Auteurs: Beatriz G. Bernardes, Sara Baptista-Silva, Carlos Illanes-Bordomás, Rui Magalhães, Juliana Rosa Dias, Nuno M. F. Alves, Raquel Costa, Carlos A. García-González, Ana Leite Oliveira
Publié dans: Pharmaceutics, Numéro 15, 2025, ISSN 1999-4923
Éditeur: MDPI AG
DOI: 10.3390/PHARMACEUTICS15112605

Semi‐Automated <scp>μCT</scp> ‐Based Modeling of Vertebral Bony Endplate Microporosity and Mechanical Properties: Linking Microstructure to Inferred Mechanical Performance

Auteurs: Ahmad Alminnawi, Gabriele Nasello, Katherine B. Crump, Benjamin Gantenbein, Jerome Noailly, Liesbet Geris
Publié dans: JOR SPINE, Numéro 9, 2026, ISSN 2572-1143
Éditeur: Wiley
DOI: 10.1002/JSP2.70204

Engineering medical-grade collagen scaffolds for bone tissue regeneration

Auteurs: Diana Pacheco, A.S. Silva-Barroso, Alexandre Gomes, Marta Lourenço, Margarida Franco, Ruben Silva, Artur Mateus, Telma Encarnação, Abílio J.F.N. Sobral, Nuno Alves, Antonio Gloria, Tatiana M. Fernandes Patrício
Publié dans: Materials & Design, Numéro 261, 2026, ISSN 0264-1275
Éditeur: Elsevier BV
DOI: 10.1016/J.MATDES.2025.115282

3D Tumor-Engineered Model Replicating the Osteosarcoma Stem Cell Niche and In Vivo Tumor Complexity

Auteurs: Giada Bassi, Arianna Rossi,Elisabetta Campodoni, Monica Sandri, Patrizia Sarogni, Stefania Fulle, Valerio Voliani, Silvia Panseri and Monica Montesi
Publié dans: ACS Applied Materials & Interfaces, Numéro 16(41), 55011–55026, 2024, ISSN 1944-8252
Éditeur: ACS Publications
DOI: 10.1021/ACSAMI.4C02567

Magnesium oxide coatings on thermoplastic polyurethane as a key approach to prevent catheter-associated infections

Auteurs: Tatiana Padrão, Fernando J. Monteiro, Susana R. Sousa, Juliana R. Dias
Publié dans: Ceramics International, Numéro 51, 2026, ISSN 0272-8842
Éditeur: Elsevier BV
DOI: 10.1016/J.CERAMINT.2025.01.376

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