Project description
Confronting the global weight crisis
In a world grappling with escalating obesity rates, it is necessary to revolutionise weight management by unravelling the intricate web of determinants contributing to the global epidemic of overweight and obesity. The rise of overweight and obesity poses a formidable challenge to public health, demanding innovative solutions. With this in mind, the EU-funded BETTER4U project seeks to dissect the polygenic background of weight gain, employing advanced AI technologies and global collaboration. Its ambitious objectives include developing a personalised intervention methodology, deploying real-time monitoring tools and conducting a comprehensive clinical trial. BETTER4U envisions not just understanding the problem but offering tangible, globally adaptable solutions, marking a significant stride towards a healthier future.
Objective
BETTER4U aims at the identification and personalized management of all weight gain determinants to battle the increasingly rising numbers of overweight/obesity, via homogenous, globally adaptable and practically assessed public health initiatives and key interventions. Building on previous key projects and biobanks, the project will focus on the hitherto neglected impact of the polygenic background of weight gain on the effectiveness of lifestyle interventions for weight management in people with overweight/obesity. BETTER4U aims to probe into the global obesity challenge, study the problem and offer solutions in a tangible realistic way with the assistance of modern AI technologies and the contribution of experts around the world. BETTER4U will be realized through the following objectives: 1. To comprehensively understand and decipher genetics, metabolomics, microbiota, socio-economic, geographical, cultural and lifestyle features linked to weight gain throughout the life course, via meta-analyses (BETTER4U data from >50 studies, >1 million individuals) and extensive literature meta-review. 2.To develop the BETTER4U intervention methodology for weight gain prevention, based on a causal AI model of obesity determinants and a pilot study in 7 European countries. 3.To deploy technology-assisted, real-time monitoring tools to measure detailed behavioral indicators and their relation to the environmental context. 4.To evaluate the efficacy of the novel BETTER4U intervention methodology in a controlled, randomized clinical trial, based on individually-tailored recommendations for lifestyle change. 5.To maximize transferability and applicability of the BETTER4U intervention methodology by identifying implementation barriers and facilitators, as well as to evaluate implementation outcomes in both participants and stakeholders. 6. To develop and disseminate the BETTER4Uobesity prevention intervention methodology guidelines using a people-centred, sustainable care approach.
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Keywords
Programme(s)
Topic(s)
Funding Scheme
HORIZON-RIA - HORIZON Research and Innovation ActionsCoordinator
176 71 ATHINA
Greece
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Participants (23)
2730 036 Barcarena Oeiras
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69310 Pierre-Benite
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3400 Hillerod
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1040 BRUXELLES
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
57001 Thermi Thessaloniki
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17177 Stockholm
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1090 Wien
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1678 Nicosia
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00014 Helsingin Yliopisto
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31080 Pamplona
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9000 Gent
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03-815 WARSZAWA
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51005 Tartu
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85764 Neuherberg
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1081 HV Amsterdam
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D02 N820 Dublin
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1010 Wien
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7610001 Rehovot
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171 21 Nea Smyrni
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
09124 Cagliari
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300358 TIMISOARA
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546 36 THESSALONIKI
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33520 Tampere
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Partners (4)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
3012 Bern
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
4066 Herston
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
BD9 6RJ Bradford
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
E1 4NS London
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