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Preventing obesity through Biologically and bEhaviorally Tailored inTERventions for you - BETTER4U

Project description

Confronting the global weight crisis

In a world grappling with escalating obesity rates, it is necessary to revolutionise weight management by unravelling the intricate web of determinants contributing to the global epidemic of overweight and obesity. The rise of overweight and obesity poses a formidable challenge to public health, demanding innovative solutions. With this in mind, the EU-funded BETTER4U project seeks to dissect the polygenic background of weight gain, employing advanced AI technologies and global collaboration. Its ambitious objectives include developing a personalised intervention methodology, deploying real-time monitoring tools and conducting a comprehensive clinical trial. BETTER4U envisions not just understanding the problem but offering tangible, globally adaptable solutions, marking a significant stride towards a healthier future.

Objective

BETTER4U aims at the identification and personalized management of all weight gain determinants to battle the increasingly rising numbers of overweight/obesity, via homogenous, globally adaptable and practically assessed public health initiatives and key interventions. Building on previous key projects and biobanks, the project will focus on the hitherto neglected impact of the polygenic background of weight gain on the effectiveness of lifestyle interventions for weight management in people with overweight/obesity. BETTER4U aims to probe into the global obesity challenge, study the problem and offer solutions in a tangible realistic way with the assistance of modern AI technologies and the contribution of experts around the world. BETTER4U will be realized through the following objectives: 1. To comprehensively understand and decipher genetics, metabolomics, microbiota, socio-economic, geographical, cultural and lifestyle features linked to weight gain throughout the life course, via meta-analyses (BETTER4U data from >50 studies, >1 million individuals) and extensive literature meta-review. 2.To develop the BETTER4U intervention methodology for weight gain prevention, based on a causal AI model of obesity determinants and a pilot study in 7 European countries. 3.To deploy technology-assisted, real-time monitoring tools to measure detailed behavioral indicators and their relation to the environmental context. 4.To evaluate the efficacy of the novel BETTER4U intervention methodology in a controlled, randomized clinical trial, based on individually-tailored recommendations for lifestyle change. 5.To maximize transferability and applicability of the BETTER4U intervention methodology by identifying implementation barriers and facilitators, as well as to evaluate implementation outcomes in both participants and stakeholders. 6. To develop and disseminate the BETTER4Uobesity prevention intervention methodology guidelines using a people-centred, sustainable care approach.

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-RIA - HORIZON Research and Innovation Actions

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Call for proposal

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(opens in new window) HORIZON-HLTH-2022-STAYHLTH-01-two-stage

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Coordinator

CHAROKOPEIO PANEPISTIMIO
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 834 562,50
Address
ELEFTHERIOU VENIZELOU 70
176 71 ATHINA
Greece

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Region
Αττική Aττική Νότιος Τομέας Αθηνών
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 834 562,50

Participants (25)

Partners (4)

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