Applying ARtificial Intelligence to Define clinical trajectorieS for personalized predicTiOn and early deTEctiOn of comorbidiTy and muLtimorbidiTy pattErnS

Project Information

ARISTOTELES

Grant agreement ID: 101080189

DOI

10.3030/101080189

EC signature date 9 October 2023

Start date 1 November 2023

End date 31 October 2028

Funded under

• Health

Total cost

€ 4 093 462,50

EU contribution

€ 4 093 462,50

Coordinated by

UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA
Italy

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (1)

Plan for the dissemination and exploitation including communication activities

The report describes the dissemination, exploitation and Communication measures that are planned, and the target group(s) addressed (e.g., scientific community, end users,financial actors, public at large).

Websites, patent fillings, videos etc. (1)

Project website and logo development

Project image for wide communication

Publications

Peer reviewed articles (18)

Trends in Cardiovascular Medicine

Author(s): Piotr Jemielita; Gregory Y.H. Lip; Anna Kurasz; Michał Święczkowski; Adrianna Krepsztul-Jemielita; Sławomir Dobrzycki; Łukasz Kuźma
Published in: Trends in Cardiovascular Medicine, Issue 35, 2025, ISSN 1050-1738
Publisher: Elsevier
DOI: 10.1016/J.TCM.2024.07.001

Risk Factors and Prognosis of New-Onset Atrial Fibrillation in Sepsis

Author(s): Yuxin Huo, Hiroyuki Yoshimura, Arturo Gonzalez-Izquierdo, Gregory Y.H. Lip, Floriaan Schmidt, Rui Providencia
Published in: JACC: Advances, Issue 4, 2025, ISSN 2772-963X
Publisher: Elsevier BV
DOI: 10.1016/J.JACADV.2025.101681

Detection of subclinical atrial fibrillation with cardiac implanted electronic devices: What decision making on anticoagulation after the NOAH and ARTESiA trials?

Author(s): Boriani G.; Gerra L.; Mei D. A.; Bonini N.; Vitolo M.; Proietti M.; Imberti J. F.
Published in: European Journal of Internal Medicine, Issue 123, 2024, ISSN 1879-0828
Publisher: ScienceDirect
DOI: 10.1016/J.EJIM.2024.01.002

Refining the CHA2DS2VASc risk stratification scheme: shall we drop the sex category criterion?

Author(s): Hiroyuki Yoshimura, Rui Providencia, Chris Finan, Amand Floriaan Schmidt, Gregory Y H Lip
Published in: Europace, Issue 26, 2024, ISSN 1099-5129
Publisher: Oxford University Press (OUP)
DOI: 10.1093/EUROPACE/EUAE280

Clustering of electronic health records in atrial fibrillation patients and impact on prognosis and patient trajectories: a UK linked-dataset study

Author(s): Zengqi Zhang, Hiroyuki Yoshimura, Dionisio Acosta-Mena, Carina Teixeira, Chris Finan, Gregory Y H Lip, A Floriaan Schmidt, Rui Providencia
Published in: European Heart Journal - Digital Health, 2025, ISSN 2634-3916
Publisher: Oxford University Press (OUP)
DOI: 10.1093/EHJDH/ZTAF032

Initial blood pressure and adverse cardiac events following acute ischaemic stroke: An individual patient data pooled analysis from the VISTA database

Author(s): Hironori Ishiguchi; Bi Huang; Wahbi K. El-Bouri; Jesse Dawson; Gregory Y. H. Lip; Azmil H. Abdul-Rahim; K.R. Lees (Chair); A. Alexandrov; P.M. Bath; E. Bluhmki; N. Bornstein; C. Chen; L. Claesson; J. Curram; S.M. Davis; H-C. Diener; G. Donnan; M. Fisher; M. Ginsberg; B. Gregson; J. Grotta; W. Hacke; M.G. Hennerici; M. Hommel; M. Kaste; P. Lyden; J. Marler; K. Muir; C. Roffe; R. Sacco; A . Shuaib; P. Teal; N. Venketasubramanian; N.G. Wahlgren; S. Warach
Published in: European Stroke Journal, 2024, ISSN 2396-9881
Publisher: Sage
DOI: 10.1177/23969873241296391

2024 Chinese Expert Consensus Guidelines on the Diagnosis and Treatment of Atrial Fibrillation in the Elderly, Endorsed by Geriatric Society of Chinese Medical Association (Cardiovascular Group) and Chinese Society of Geriatric Health Medicine (Cardiovascular Branch): Executive Summary

Author(s): Yutang Wang; Yutao Guo; Mingzhao Qin; Jin Fan; Ming Tang; Xinjun Zhang; Hao Wang; Xiaoying Li; Gregory Y. H. Lip
Published in: Thrombosis and Haemostasis, Issue 124, 2024, ISSN 2567-689X
Publisher: Thieme
DOI: 10.1055/A-2325-5923

Internal and emergency medicine

Author(s): Lam, S.H.M.; Romiti, G.F.; Olshansky, B.; Chao, T.F.; Huisman, M.V.; Lip, G.Y.H.
Published in: Internal and Emergency Medicine, Issue 19, 2024, ISSN 1828-0447
Publisher: Springer
DOI: 10.1007/S11739-024-03629-0

Causes of death in patients with atrial fibrillation in the UK: a nationwide electronic health record study

Author(s): Yongtong Lai, Hiroyuki Yoshimura, Nadine Zakkak, Eloi Marijon, Anwar Chahal, Gregory Y H Lip, Floriaan Schmidt, Rui Providencia
Published in: European Heart Journal Open, Issue 5, 2025, ISSN 2752-4191
Publisher: Oxford University Press (OUP)
DOI: 10.1093/EHJOPEN/OEAE103

Journal of Cardiovascular Electrophysiology

Author(s): Mark T. Mills; Peter Calvert; Gregory Y. H. Lip; Vishal Luther; Dhiraj Gupta
Published in: Journal of Cardiovascular Electrophysiology, Issue 35, 2024, ISSN 1045-3873
Publisher: Wiley
DOI: 10.1111/JCE.16345

Atrial Fibrillation in Asia and Globally

Author(s): Gregory Y.H. Lip
Published in: JACC: Asia, 2025, ISSN 2772-3747
Publisher: Elsevier
DOI: 10.1016/J.JACASI.2024.11.013

Nature Medicine

Author(s): Ming Chu; Shimeng Zhang; Jinlong Gong; Shu Yang; Gang Yang; Xingxing Sun; Dan Wu; Yaodongqin Xia; Jincheng Jiao; Xiafeng Peng; Zhihang Peng; Li Hong; Zhirong Wang; Mingfang Li; Gregory Y. H. Lip; Minglong Chen; Yutao Guo; Xinfeng Liu; Shanshan Lu
Published in: Nature Medicine, Issue 31, 2025, ISSN 1078-8956
Publisher: Springer
DOI: 10.1038/S41591-025-03511-2

Performance of HAS-BLED and DOAC scores to predict major bleeding events in atrial fibrillation patients treated with direct oral anticoagulants: A report from a prospective European observational registry

Author(s): Davide Antonio Mei; Jacopo Francesco Imberti; Niccolò Bonini; Giulio Francesco Romiti; Bernadette Corica; Marco Proietti; Marco Vitolo; Gregory Y.H. Lip; Giuseppe Boriani
Published in: European Journal of Internal Medicine, Issue 128, 2024, ISSN 1879-0828
Publisher: Elsevier
DOI: 10.1016/J.EJIM.2024.06.022

Cancer incidence and mortality among patients with new-onset atrial fibrillation: A population-based matched cohort study

Author(s): Nadine Zakkak, Matthew Barclay, Arturo Gonzalez-Izquierdo, Amand Floriaan Schmidt, Gregory Y.H. Lip, Georgios Lyratzopoulos, Rui Providencia
Published in: Neoplasia, Issue 59, 2025, ISSN 1476-5586
Publisher: Elsevier BV
DOI: 10.1016/J.NEO.2024.101080

A European-Multicenter Network for the Implementation of Artificial Intelligence to Manage Complexity and Comorbidities of Atrial Fibrillation Patients: The ARISTOTELES Consortium

Author(s): Boriani, Giuseppe; Mei, Davide Antonio; Lip, Gregory
Published in: Thrombosis and Haemostasis, Issue 125, 2025, ISSN 2567-689X
Publisher: Thieme
DOI: 10.1055/A-2508-5708

Refining the Cardiovascular Health Score in Patients With Type 2 Diabetes

Author(s): Steven Ho Man Lam; Uazman Alam; Gregory Yoke Hong Lip
Published in: JACC: Asia, Issue 4, 2024, ISSN 2772-3747
Publisher: Elsevier
DOI: 10.1016/J.JACASI.2024.04.004

Artificial intelligence in patients with atrial fibrillation to manage clinical complexity and comorbidities: the ARISTOTELES project

Author(s): Giuseppe Boriani, Davide Antonio Mei, Gregory Y H Lip, null null, Niccolò Bonini, Marco Vitolo, Jacopo Francesco Imberti, Nadja Saendig, Martin Bøgsted, Charles Vesteghem, Katja Hose, Tomer Sagi, Soeren Johnsen, Michael Eriksen, Peter Brønnum Nielsen, Rasmus Froberg Brøndum, Simon Christian Dahl, Thomas Stampe Rasmussen, Francisco Marin Ortuno, Vanessa Roldan, Jose Miguel Rivera Caravaca, Laura Vivani, Silvia Anastasia, Veronica Christofidis, Aleksandra Pajic, Andrea Martínez, Amparo Roca, Antonio Vicente, Jose Manuel Asensio, Salomé Sepúlveda, Soren Holm, Hilde Henriksen, Eirik Ivarrud, Elisabeth Authen Sethre, Jorunn Hestenes Larsen, Anca Dan, Andrei Dan, Christos Lionis, George Kochiadakis, Marilena Anastasaki, Maria Marketou, Gregory Chlouverakis, Myron Galenianos, Irini Vasilaki, Panepistimio Kritis, Martina Ceseri, Marco Gorini, Francesco Orso, Donata Lucci, Aldo Maggioni, Andrea Lorimer, Gilles Paubert, Stephanie Collin, Costantino De Palma, Lino Manuel Martins Gonçalves, Sandra Gervasio, Ines Costa, Manuel Marina Breysse, Irene Sánchez Rodríguez, Raquel Toribio Fernández, Isabel Sierra Munoz, Francois De guio, Manuel Lara, Mirko Orsini, Marco Monari, Glenn Roberts, Chris Appleton, John Loftus, Iain Buchan, Wahbi El-Bouri, Gary Leeming, Deirdre Lane, Yalin Zheng, David McVey, Dale Stephens, John Ainsworth, Liz Fay, Philip Couch, Edd Tempest, Rhona Stephen, Rebecca White, Ivan Olier-Caparroso, Sandra Ortega-Martorell, Ryan Bellfield, Brittany Mason, Amand Floriaan Schmidt, Rui Bebiano Da Providencia E Costa, Johanna Ponnuthurai
Published in: European Heart Journal, 2024, ISSN 0195-668X
Publisher: Oxford University Press (OUP)
DOI: 10.1093/EURHEARTJ/EHAE792

European Journal of Clinical Investigation

Author(s): Yang Liu; Yang Chen; Ivan Olier; Sandra Ortega‐Martorell; Bi Huang; Hironori Ishiguchi; Ho Man Lam; Kui Hong; Menno V. Huisman; Gregory Y. H. Lip
Published in: European Journal of Clinical Investigation, Issue 55, 2025, ISSN 0014-2972
Publisher: Wiley
DOI: 10.1111/ECI.14371