Next-generation models and genetic therapies for rare neuromuscular diseases

Informations projet

MAGIC

N° de convention de subvention: 101080690

DOI

10.3030/101080690

Date de signature de la CE 28 Avril 2023

Date de début 1 Juin 2023

Date de fin 31 Mai 2027

Financé au titre de

• Health

Coût total

€ 6 553 472,00

Contribution de l’UE

€ 6 553 472,00

Coordonné par

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Data Management Plan (1)

Data Management Plan

A Data Management Plan (DMP) following the HE guidelines will address the relevant aspects of making data FAIR, including what data the project will generate, whether and how it will be made accessible for verification and re-use, and how it will be curated and preserved. The DMP will also include details of the security measures to be taken in the context of the transfer of data from non-EU countries to prevent unauthorised access to personal data.

Websites, patent fillings, videos etc. (1)

Project website

Report on the design, set up and maintenance of the website

Documents, reports (4)

3D muscle generation

Protocol to generate advanced disease-specific 3D muscle models

Exploitation Plan (first release)

This plan is a strategic document indicating how the consortium establishes the basis for the intellectual property management and exploitation of key research outputs. It will include a preliminary analysis of analysis of both the research and market landscapes

Communication and Dissemination plan (first release)

Review and update (where necessary) of the original Communication and Dissemination Plan included in Annex 1

Perfusion, stimulation & miniaturisation of 3D muscles

Method to perfuse, stimulate and miniaturise 3D muscle models

Publications

Peer reviewed articles (2)

Low-cost, versatile, and highly reproducible microfabrication pipeline to generate 3D-printed customised cell culture devices with complex designs

Auteurs: Cathleen Hagemann, Matthew C. D. Bailey, Eugenia Carraro, Ksenia S. Stankevich, Valentina Maria Lionello, Noreen Khokhar, Pacharaporn Suklai, Carmen Moreno-Gonzalez, Kelly O’Toole, George Konstantinou, Christina L. Dix, Sudeep Joshi, Eleonora Giagnorio, Mads S. Bergholt, Christopher D. Spicer, Albane Imbert, Francesco Saverio Tedesco, Andrea Serio
Publié dans: PLOS Biology, Numéro 22, 2024, ISSN 1545-7885
Éditeur: Public Library of Science (PLoS)
DOI: 10.1371/journal.pbio.3002503

Generation of a human induced pluripotent stem cell line (CRICKi021-A) from a patient with Ullrich congenital muscular dystrophy carrying a pathogenic mutation in the COL6A1 gene

Auteurs: Yunsong Jiang, Liani G. Devito, Francesco Muntoni, Lyn Healy, Francesco Saverio Tedesco
Publié dans: Stem Cell Research, Numéro 83, 2025, ISSN 1873-5061
Éditeur: Elsevier BV
DOI: 10.1016/j.scr.2024.103648