Project description
Advancing biobanking protocols
Scientific studies often rely on patient samples to validate preclinical results and provide valuable insight into disease emergence and progression. Similarly, the discovery of disease biomarkers requires patient samples usually stored in biorepositories known as biobanks. However, processing biological samples is laborious and involves expert staff. The ERC-based ARTS project aims to change this through an automated technology based on augmented reality that is user friendly and can be streamlined across hospitals. Such a platform, which enables monitoring of sample processing, will be more sustainable and cost-effective and offer high-quality tissues for research purposes.
Objective
Large scale biobanks are essential to meet the world-wide demand for high quality tissues to understand the development and progression of disease, or discover and validate novel biomarkers. Current biobanking protocols for harvesting and processing tissue are manual and therefore rely on experienced and costly on-site personnel. Imagine the possibilities of scientific discoveries in personalized diagnostics, prognostics and treatment if high-quality tissues could be made available from several hospitals using streamlined, harmonized and automated biobanking protocols, that would also allow for maximal utilization of this precious material. In this PoC, we propose a shift from a human centered to a semi- or fully automated tissue harvesting and processing protocol. Specifically, we propose to develop further, test and validate (from TRL4 to TRL7) an Augmented Reality enhanced and automated Tissue Sampler (ARTS), a technology that is cost-effective, simple to operate, and allows for maximal tissue utilization. The ARTS prototype was developed within my ongoing ERC StG and already enables sub-samples to be selected from tissue based on invisible features such as diseased and non-diseased cells – one of the general challenges of biobanking today. In this PoC, we will include comprehensive process monitoring and sample tracking features such as position, temperature and processing time to allow automated sub-sampling while ensuring operator quality assurance with minimal hands-on time. We will also incorporate a tested user-friendly interface ready for industry and a potential spin-off company. ARTS will allow biobanks to serve customers with specific and high-quality targeted sub-samples which will enhance the value of the material through increased reproducibility, faster processing and more efficient utilization. In addition, ARTS will relieve financial burden and achieve more long-term sustainability for biobanks, which typically depend on public funding.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2022-POC2
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
7491 Trondheim
Norway
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.