Description du projet
Un agent cicatrisant rentable
Les plaies complexes telles que les ulcères diabétiques ou veineux, ou les plaies chroniques dues à des brûlures sont difficiles à traiter et leur guérison est lente, ce qui augmente le risque d’infection. L’argent est généralement utilisé comme agent antimicrobien dans le traitement des infections des plaies. Sa production est cependant coûteuse et peu respectueuse de l’environnement. Pour relever ce défi médical, le projet NABIHEAL, financé par l’UE, entend développer des matériaux multifonctionnels basés sur la nanotechnologie comme alternative abordable à l’argent pour la cicatrisation des plaies. Les biomatériaux proposés permettront également la libération contrôlée de molécules thérapeutiques dans les pansements, empêchant ainsi la formation de biofilms et facilitant la cicatrisation.
Objectif
Complex wounds impact the quality of life of more than 2% of total population in developed countries being a global health problem with significantly impacts on health care economy. Complex wounds, including chronic wounds or major burns, are highly susceptible to microbial infection and biofilm formation, difficult to treat. Silver is a metal widely used in antimicrobial products to treat wound infections. However, silver-based products are expensive, and show several drawbacks due to costs, and environmental and safety concerns. NABIHEAL project will develop, from PoC (TRL3) to preclinical regulatory (TRL5), multifunctional biomaterials to solve some of the unmet medical needs in wound management, obtaining affordable treatments of wound infections or prevention of complications during all phases of wound healing. At short and medium term, NABIHEAL will end up with at least two innovative multifunctional wound healing biomaterials, using affordable EU-based manufacturing technologies. At long term, NABIHEAL could become a game-change alternative to silver in wound healing dressings. A consortium composed by 5 SME and 9 academic institutions, with expertise in wound healing product development, evaluation and commercialization, nanotechnology, safety, and regulatory will join forces to address this ambitious objective.
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RIA - Research and Innovation actionCoordinateur
28029 Madrid
Espagne