CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.
Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .
Livrables
] In alignment with the Industry Commons initiative, MACRAMÉ will build on the results of Task 1.2 to plan and guide the specific cooperation with and dissemination to related sectors and projects; this task will (a) elaborate concepts for engagement with industry communities and their related policy-informing and –making bodies, standardising (i.e. ISO, CEN, nat. bodies) and harmonising (i.e. OECD) bodies, and related projects (i.e. Horizon 2020/Europe), (b) identify stakeholders and organise workshops, and (c) set-up a strategic MACRAMÉ Engagement Roadmap, which builds on the successful ‘REFINE Knowledge Exchange’- and the ‘NanoHarmony’-engagement-processes, and sets sequence/‘time-dependent’ criteria for the MACRAMÉ communication actions in alignment with WP6. The Roadmap will include a dissemination plan for the data-driven hyperconnectivity and interoperability (WP3), and coordinate the execution of the prescribed communication in other WPs (i.e. concerning standardisation- and harmonisation-bodies). The 1st MACRAMÉ Risk Assessors Summit will be held in collaboration with a WP5-standardisation & harmonisation workshop (M12, hosted by BAuA), to reflect with stakeholders from academia, industry, and regulation and standardisation agencies on (a) the status and needs of the regulatory frameworks for the safety of AdMas during the life-cycle of a product, and (b) how the Project plans contribute to this topic. The 2nd MACRAMÉ Risk Assessor Summit (M36) will discuss the MACRAMÉ results and lessons learned with all relevant stakeholders to propose future actions. It will be held at the OECD (alternatively at LIST or RIVM).
Report on the MACRAMÉ Control Material Library (s’ouvre dans une nouvelle fenêtre)Task 2.1 will generate and characterise a Control Material Library (CML) for AdMas representative of the MACRAMÉ Use-Cases, including (i) the AdMas (e.g. FLG, MLG, GO, CNTs, PLGA NPs), (ii) representative finished products composed of matrices with/without the incorporated AdMas, (iii) AdMas and finished products subjected to simulated controlled ageing, incineration or pyrolysis, and (iv) materials with known toxicity, possibly belonging to AdMas that will serve as benchmark materials in Task 2.3. The materials will be characterised in their pristine state or after incubation in complex environmental/biological matrices. For the physical-chemical characterisation of the critical attributes of the materials included in the CML, advanced methods (incl. SEM, SEM/EDS, AFM, optical microscopy and their combination toward correlative approaches based on constellation matching algorithms, XPS, SMLS and cryo-TEM, DLS, NTA, EDS or Raman) will be used, and alternative methodologies to the gold standard approaches will be developed; this will allow the characterisation of the following attributes: (i) size, (ii) lateral size, (iii) oxidation state (e.g. for GRM) (iv) physical stability in environmental media and biological fluids, (v) distribution of AdMas in the finished products, and (vi) propensity of AdMas to degradation.
Summary Report about the 1st Risk Assessors Summit (s’ouvre dans une nouvelle fenêtre)] In alignment with the Industry Commons initiative, MACRAMÉ will build on the results of Task 1.2 to plan and guide the specific cooperation with and dissemination to related sectors and projects; this task will (a) elaborate concepts for engagement with industry communities and their related policy-informing and –making bodies, standardising (i.e. ISO, CEN, nat. bodies) and harmonising (i.e. OECD) bodies, and related projects (i.e. Horizon 2020/Europe), (b) identify stakeholders and organise workshops, and (c) set-up a strategic MACRAMÉ Engagement Roadmap, which builds on the successful ‘REFINE Knowledge Exchange’- and the ‘NanoHarmony’-engagement-processes, and sets sequence/‘time-dependent’ criteria for the MACRAMÉ communication actions in alignment with WP6. The Roadmap will include a dissemination plan for the data-driven hyperconnectivity and interoperability (WP3), and coordinate the execution of the prescribed communication in other WPs (i.e. concerning standardisation- and harmonisation-bodies). The 1st MACRAMÉ Risk Assessors Summit will be held in collaboration with a WP5-standardisation & harmonisation workshop (M12, hosted by BAuA), to reflect with stakeholders from academia, industry, and regulation and standardisation agencies on (a) the status and needs of the regulatory frameworks for the safety of AdMas during the life-cycle of a product, and (b) how the Project plans contribute to this topic. The 2nd MACRAMÉ Risk Assessor Summit (M36) will discuss the MACRAMÉ results and lessons learned with all relevant stakeholders to propose future actions. It will be held at the OECD (alternatively at LIST or RIVM).
Report on Stakeholder Involvement & Knowledge Transfer in the first 18 month (s’ouvre dans une nouvelle fenêtre)Task 5.2 will establish link to relevant activities and initiatives as the Malta-Initiative, VAMAS, EURL ECVAM, the NanoSafety Cluster projects, EURAMET, the Graphene Flagship, NCI-NCL, and PARC to ensure cooperation on (ongoing) standardisation and harmonisation advancements. Sub-Task 5.2.1: MACRAMÉ Workshops - Three MACRAMÉ Workshops (M12, M22, M34) will give an overview of ongoing harmonisation and standardisation projects in the field of nano- and AdMas. Current needs and issues will be discussed, including opportunities for projects to present their work in open sessions and for expert input in closed sessions. Two virtual workshops and one face-to-face (back-to-back with the 1st MACRAMÉ Risk Assessors Summit) are planned. Sub-Task 5.2.2: Improve Knowledge on Harmonisation & Standardisation activities – [Lead: LIST] This Sub-Task will improve the knowledge of industry, scientists and researchers on the harmonisation and standardisation landscape, processes and impact to increase the visibility of these key initiatives and the involvement of new experts on targeted actions. The different bodies, their respective roles and interactions will be introduced and the steps necessary for the harmonisation and standardisation process explained. The Task will use the training material produced in NanoHarmony on the OECD process of TG development, and further broaden the focus to standardisation and validation topics. OECD, ISO, CEN, ASTM, VAMAS and EURL ECVAM representatives will be invited to give insights and thus raise awareness of harmonisation and standardisation processes. Five MACRAMÉ Webinars (M12, M17, M24, M28, M35) will be held, as well as several sessions at summer schools and relevant meetings.
Sampling & Sample-Provision Protocols for AdMas in complex Matrices (s’ouvre dans une nouvelle fenêtre)Based on the collaboratively re-fined R&I Strategy and its benchmarks, Task 4.1 will define and agree sampling protocols tailored to the exposure points, and the test requirements (e.g. blinding for validation studies (LIST)), and will collect and deliver the required quantities of material to the WP2 partners for investigation and characterisation: Sub-Task 4.1.1: Develop & refine AdMa@CM Sampling & Sample-Provision Protocols (M02–M34) - Sampling and sample-provision protocols for AdMas and AdMa-bearing composites (i.e. AdMa@CM), as well as other relevant control samples, will be developed and implemented, in agreement with WP2 partners; these will be based on the specific Exposure Points conditions (see Figure 3). Subtask 4.1.2: Collect and deliver Use-Case Samples (M02-34) - Industrial partners will provide both pristine materials as used in their products, and samples collected from selected release hotspots to provide a representative selection of the value-chains (e.g. consumer use and end-of-life (incineration and landfilling)), following all special requirements for sample collection and preparation, ensuring sufficient material is delivered for characterisation, analysis and evaluation in WP2.
A Project Corporate Identity (CI) will be developed; it will be composed of a Project logo, the layout for flyers and website, a template for presentations, and a layout for the Project’s newsletters. The website will be launched in M01 (initial Project website), later updated to a full website in M05. Printed and digital means will be used for targeted communication and dissemination (Section 2.2).
This Task will provide a one-stop-shop for harmonised and interoperable MACRAMÉ (Meta)Data-Exchange with all customised tools for curation, storing and sharing: the provision will be made in two parts: (i) Providing, integrating and customising tools for information management and sharing, (electronic lab notebooks, instance maps & data packages) optimised for different tasks & users: All tools will be adapted to address the requirements of the improved reporting guidelines developed in Task 3.2. Advanced cloud technology will allow collaborative research on multiple levels (e.g., within single or multiple-partner teams, for case-study and/or round-robin work) in a secure and traceable way. (ii) Direct linking to analysis and modelling software from Task 3.3 and 3.4 and standard data resources for long-term storage and FAIR sharing of data: in collaboration with Task 3.2, MACRAM’s data concepts and guidance will be implemented in the form of extended reporting and exchange formats (machine-readable, semantically annotated) interoperable and aligned with major European Initiatives (IndustryCommons, EU NanoSafety Cluster and European Materials Characterisation Council). Automatic data upload to standard repositories (NanoCommons, eNanomapper, CHADA repositories) will be possible, initiated by the data owner. The data-management and -sharing processes adopted by the MACRAMÉ consortium will be documented and constantly updated in the research output management plan (ROMP), an extension of a DMP, which will guide partners in their preparation of technology documentation, protocols, (meta)data, software and results. The ROMP will also provide measures for addressing problems or challenges encountered in data curation and management.
Publications
Auteurs:
Hicham Meskher; Amrit Kumar Thakur; Soumya Kanti Hazra; Md. Shamim Ahamed; Ahmed Mortuza Saleque; Qusay F. Alsalhy; Muhammad Wakil Shahzad; Md. Nahian Al Subri Ivan; Shuvra Saha; Iseult Lynch
Publié dans:
Environmental Science: Nano, 2025, ISSN 0000-0000
Éditeur:
Royal Society of Chemistry
DOI:
10.1039/D4EN00427B
Auteurs:
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr
Publié dans:
Advanced Science, 2025, ISSN 2198-3844
Éditeur:
Wiley
DOI:
10.1002/ADVS.202516401
Auteurs:
Steffi Friedrichs; Christian Seitz; Eric Bleeker; Rob Vandebriel; Samia Ouhajji; Evert Duistermaat; Martin Wiemann; Antje Vennemann; Alberto Katsumiti; Tina Buerki-Thurnherr; Govind Gupta; Peter Wick; Luis Mauricio Ortiz-Galvez; Jimeng Wu; Klaus-Michael Weltring; Daniel Haase; Elisabeth Heunisch; Anna Pohl; Katie Reilly; Zhiling Guo; Iseult Lynch; Thomas Exner; Birgit Hagenhoff; Daniel Breitenstein
Publié dans:
Computational and Structural Biotechnology Journal, 2025, ISSN 0000-0000
Éditeur:
Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology.
DOI:
10.1016/J.CSBJ.2025.03.032
Auteurs:
Ziting Wang; Jimmy Vernaz; Nikolaos Tagaras; Bernadett Boda; Tina Buerki-Thurnherr; Giacomo Reina; Vera M. Kissling; Samuel Constant; Govind Gupta; Peter Wick
Publié dans:
ACS Nano, 2025, ISSN 0000-0000
Éditeur:
ACS Publications
DOI:
10.1021/ACSNANO.5C01981
Auteurs:
Dirk Broßell; Asmus Meyer-Plath; Elisabeth Heunisch; Kerstin Kämpf; Andrea Haase; Martin Wiemann
Publié dans:
Particle and Fibre Toxicology, 2025, ISSN 0967-0912
Éditeur:
Institute of Materials
DOI:
10.21203/RS.3.RS-8317185/V1
Auteurs:
Exner, Thomas E.; Dokler, Joh; Friedrichs, Steffi; Seitz, Christian; Bleken, Francesca L.; Friis, Jesper; Hagelien, Thomas F.; Mercuri, Francesco; Costa, Anna L.; Furxhi, Irini; Sarimveis, Haralambos; Afantitis, Antreas; Marvuglia, Antonino; Larrea-Gallegos, Gustavo M.; Serchi, Tommaso; Serra, Angela; Greco, Dario; Nymark, Penny; Himly, Martin; Wiench, Karin; Watzek, Nico; Schillinger, Eva-Kathrin; Gavillet, Jérôme; Lynch, Iseult; Karwath, Andreas; Haywood, Alexe L.; Gkoutos, Georgios V.; Hischier, Roland
Publié dans:
Computational and Structural Biotechnology Journal, 2025, ISSN 2001-0370
Éditeur:
Elsevier B.V.
DOI:
10.1016/J.CSBJ.2025.03.019
Auteurs:
F. R. Cassee et al.
Publié dans:
Computational and Structural Biotechnology Journal, Numéro 25, 2024, ISSN 2001-0370
Éditeur:
Elsevier
DOI:
10.1016/j.csbj.2024.05.018
Auteurs:
I. Furxhi et al.
Publié dans:
RSC Sustainability, Numéro 1, 2023, ISSN 2753-8125
Éditeur:
RSC
DOI:
10.1039/d2su00101b
Auteurs:
Gabriel M. Ferraz, Jonatas S. Carvalho, Gustavo B. dos Santos, Natasha Caroline C. Sousa, Ricardo Custódio, Aline S. de Moraes, Ingrid T. de Miranda, Iseult Lynch, Roberta C. Urban
Publié dans:
Journal of the Brazilian Chemical Society, 2025, ISSN 0103-5053
Éditeur:
Sociedade Brasileira de Quimica (SBQ)
DOI:
10.21577/0103-5053.20250165
Auteurs:
Merve Tunali; Hyunjoo Hong; Luis Mauricio Ortiz-Galvez; Jimeng Wu; Yiwen Zhang; David Mennekes; Barbora Pinlova; Danyang Jiang; Claudia Som; Bernd Nowack
Publié dans:
Sustainability, 2023, ISSN 0000-0000
Éditeur:
MDPI
DOI:
10.3390/SU151914453
Auteurs:
Jimeng Wu; Peter Wick; Bernd Nowack
Publié dans:
ACS Nano, 2025, ISSN 0000-0000
Éditeur:
ACS Nano
DOI:
10.1021/ACSNANO.5C03040
Auteurs:
Eric A.J. Bleeker, Elmer Swart, Hedwig Braakhuis, María Luisa Fernández Cruz, Steffi Friedrichs, Ilse Gosens, Frank Herzberg, Keld Alstrup Jensen, Frank von der Kammer, Jolinde A.B. Kettelarij, Jose María Navas, Kirsten Rasmussen, Kathrin Schwirn, Maaike
Publié dans:
Regulatory Toxicology and Pharmacology, 2023, ISSN 0273-2300
Éditeur:
Academic Press
DOI:
10.1016/J.YRTPH.2023.105360
Auteurs:
Gupta et al.
Publié dans:
Small, Numéro 20, 2024, ISSN 1613-6829
Éditeur:
Wiley
DOI:
10.1002/smll.202308148
Auteurs:
Verónica I. Dumit, Irini Furxhi, Penny Nymark, Antreas Afantitis, Ammar Ammar, Monica J. B. Amorim, Dalila Antunes, Svetlana Avramova, Chiara L. Battistelli, Gianpietro Basei, Cecilia Bossa, Emil Cimpan, Mihaela Roxana Cimpan, Dmitri Ciornii, Anna Costa, Camilla Delpivo, Maria Dusinska, Ana Sofia Fonseca, Steffi Friedrichs, Vasile‐Dan Hodoroaba, Danail Hristozov, Panagiotis Isigonis, Nina Jeliazkova, Nikolay Kochev, Eva Kranjc, Dieter Maier, Georgia Melagraki, Anastasios G. Papadiamantis, Tomasz Puzyn, Hubert Rauscher, Katie Reilly, Araceli Sánchez Jiménez, Janeck J. Scott‐Fordsmand, Neeraj Shandilya, Hyun Kil Shin, Gergana Tancheva, Jeaphianne P. M. van Rijn, Egon L. Willighagen, Ewelina Wyrzykowska, Martine I. Bakker, Damjana Drobne, Thomas E. Exner, Martin Himly, Iseult Lynch
Publié dans:
Advanced Sustainable Systems, Numéro 10, 2026, ISSN 2366-7486
Éditeur:
Wiley
DOI:
10.1002/ADSU.202500567
Auteurs:
Grace Davies, Sarmite Kernchen, Martin G. J. Löder, Louisa Brenninkmeijer, Christian Laforsch, Stefan Krause, Iseult Lynch
Publié dans:
Microplastics and Nanoplastics, Numéro 6, 2026, ISSN 2662-4966
Éditeur:
Springer Science and Business Media LLC
DOI:
10.1186/S43591-025-00167-0
Auteurs:
Jimeng Wu, Govind Gupta, Tina Buerki-Thurnherr, Bernd Nowack, Peter Wick,
Publié dans:
NanoImpact, ISSN 2452-0748
Éditeur:
Science Direct
DOI:
10.1016/J.IMPACT.2024.100533
Auteurs:
Punz et al.
Publié dans:
Beilstein Archives, 2024, ISSN 2190-4286
Éditeur:
Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI:
10.3762/bxiv.2024.26.v1
Auteurs:
Timothy W. Gant, Alistair Boxall, Daniel Burgwinkel, Maryam Zare Jeddi, Ivo Djidrovski, Steffi Friedrichs, Barry Hardy, Thomas Hartung, Daniela Holland, Andreas Karwath, Anne Kienhuis, Nicole Kleinstreuer, Zhoumeng Lin, Emma L. Marczylo, Antonino Marvuglia, Hua Qian, Bennard van Ravenzwaay, Paul Rees, Haralambos Sarimveis, Tewes Tralau, Lucy Wilmot, Adam Zalewski, David Rouquié
Publié dans:
Archives of Toxicology, Numéro 100, 2026, ISSN 0340-5761
Éditeur:
Springer Science and Business Media LLC
DOI:
10.1007/S00204-025-04286-8
Auteurs:
T. E. Exner et al.
Publié dans:
Frontiers in Physics, Numéro 11, 2023, ISSN 2296-424X
Éditeur:
Frontiers Media
DOI:
10.3389/fphy.2023.1233879
Auteurs:
Liyan Xiao, Jinyan Pang, Zhiling Guo, Kexin Zhang, Zhiqin Xiong, Man Yang, Ji Wang, Yang Li, Iseult Lynch
Publié dans:
Environment & Health, 2026, ISSN 2833-8278
Éditeur:
American Chemical Society (ACS)
DOI:
10.1021/ENVHEALTH.5C00580
Auteurs:
Swaroop Chakraborty, Iseult Lynch
Publié dans:
Accounts of Chemical Research, Numéro 58, 2025, ISSN 0001-4842
Éditeur:
American Chemical Society (ACS)
DOI:
10.1021/ACS.ACCOUNTS.5C00587
Auteurs:
Anna Kukkola, Andrew J. Chetwynd, Stefan Krause, Iseult Lynch
Publié dans:
Journal of Hazardous Materials, Numéro 476, 2025, ISSN 0304-3894
Éditeur:
Elsevier BV
DOI:
10.1016/J.JHAZMAT.2024.135053
Auteurs:
Laura Aliisa Saarimäki; Michele Fratello; Giusy del Giudice; Emanuele Di Lieto; Antreas Afantitis; Harri Alenius; Eliodoro Chiavazzo; Mary Gulumian; Piia Karisola; Iseult Lynch; Giulia Mancardi; Georgia Melagraki; Paolo Netti; Anastasios G. Papadiamantis; Willie Peijnenburg; Hélder A Santos; Tommaso Serchi; Mohammad-Ali Shahbazi; Tobias Stoeger; Eugenia Valsami-Jones; Paola Vivo; Ivana Vinković Vrček; Ulla Vogel; Peter Wick; David A. Winkler; Angela Serra; Dario Greco
Publié dans:
Environmental Science & Technology, 2025, ISSN 0000-0000
Éditeur:
ACS Publications
DOI:
10.2139/SSRN.5066370
Auteurs:
Exner, Thomas E.; Brajnik, Maja; Friedrichs, Steffi; Dokler, Joh; Vandebriel, Rob
Publié dans:
2023
DOI:
10.5281/ZENODO.15002806
Auteurs:
Caputo, Fanny; Favre, Georges; Delcour, Simon; Wiemann, Martin; Serchi, Tommaso; Meyer-Plath, Asmus Andres; Günday-Türeli, Nazende; Weltring, Klaus-Michael; Gupta, Govind; Wick, Peter; Buerki-Thurnherr, Tina; Friedrichs, Steffi
Publié dans:
2023
DOI:
10.5281/ZENODO.15125882
Auteurs:
Ouhajji S. et al
Publié dans:
Zenodo
Éditeur:
Zenodo
DOI:
10.5281/ZENODO.204268635281/
Auteurs:
Haase, Daniel; Weltring, Klaus-Michael; Spring, Kathleen; Vandebriel, Rob; Heunisch, Elisabeth; Pohl, Anna; Bleeker, Eric A.J.; Suarez-Merino, Blanca; Durand, Cyrille; Katsumiti, Alberto; Rodríguez-Llopis, Isabel; Friedrichs, Steffi
Publié dans:
2023
DOI:
10.5281/ZENODO.15125693
Auteurs:
Suarez-Merino, Blanca; JOSHI, DEVENDRA; Durand, Cyrille; Gupta, Govind; Katsumiti, Alberto; Günday-Türeli, Nazende; Chupin, Lucie; Pohl, Anna; Heise, Martin; Vezzali, Matteo; Wick, Peter; Buerki-Thurnherr, Tina; Friedrichs, Steffi
Publié dans:
2024
DOI:
10.5281/ZENODO.15126026
Recherche de données OpenAIRE...
Une erreur s’est produite lors de la recherche de données OpenAIRE
Aucun résultat disponible