Objective
The bioreactor industry is currently flourishing with a global market valued estimated at 2.3 B€ in 2020 and predicted to exceed 6.6 B€ euro by 2030, growing at a rate of 10.7% CAGR. Despite this impressive growth, there are challenges which can significantly impede the further advancement of bioreactors: Bioproducts can be sustainable and competitive only if reliable and contamination-free production is ensured. Currently, there is no catholic solution to this issue. To this end, LIBRA project introduces a benchtop smart multi-sensing system for the in-line automatable screening of cultivation processes in bioreactors. The LIBRA sensing technology lies in the use of light based integrated on-chip, real time sensors. A novel integration procedure of the photonic platforms together with disposable microfluidic modules and biofunctionalization units will result in a modular system with interchangeable components enabling the screening of nutrients and pathogens in bioreactor samples, according to the end users need. Furthermore, the LIBRA system will be able to be attached and integrated to various bioreactor systems regardless of their form factors, spanning from stirred tank bioreactors to single use bioreactors (SUB). To achieve this, LIBRA will rely on a highly multi-disciplinary consortium comprising expertise and specialization in several fields spanning photonics, surface functionalization, microfluidics, advanced packaging and assembly, artificial intelligence and bioreactor manufacturers. The exploitable results of LIBRA are expected to disrupt the current PIC-based sensing landscape, as estimated by the two business cases stemming from the project: the market revenues one year after the end of this project are expected to be €7.8 million growing to almost €59 million in 2032, and plethora of new IP and new business opportunities for the partners involved in the joint venture of LIBRA.
Fields of science
- natural sciencescomputer and information sciencesartificial intelligence
- natural sciencesphysical sciencesclassical mechanicsfluid mechanicsmicrofluidics
- engineering and technologyenvironmental biotechnologybioremediationbioreactors
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors
- engineering and technologyindustrial biotechnologybiomaterials
Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
157 80 Athina
Greece
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Participants (10)
7521 AN Enschede
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15351 Pallini, Athina
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
00580 Helsinki
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
7521 PH Enschede
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
7521 PH Enschede
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153 41 Agia Paraskevi Athina
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
00185 Roma
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3723 MB Bilthoven
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8000 Aarhus C
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92370 Chaville
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partners (1)
2000 Neuchatel
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