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LIGHT BASED MULTISENSING DEVICE FOR SCREENING OF PATHOGENS AND NUTRIENTS IN BIOREACTORS

Objective

The bioreactor industry is currently flourishing with a global market valued estimated at 2.3 B€ in 2020 and predicted to exceed 6.6 B€ euro by 2030, growing at a rate of 10.7% CAGR. Despite this impressive growth, there are challenges which can significantly impede the further advancement of bioreactors: Bioproducts can be sustainable and competitive only if reliable and contamination-free production is ensured. Currently, there is no catholic solution to this issue. To this end, LIBRA project introduces a benchtop smart multi-sensing system for the in-line automatable screening of cultivation processes in bioreactors. The LIBRA sensing technology lies in the use of light based integrated on-chip, real time sensors. A novel integration procedure of the photonic platforms together with disposable microfluidic modules and biofunctionalization units will result in a modular system with interchangeable components enabling the screening of nutrients and pathogens in bioreactor samples, according to the end users need. Furthermore, the LIBRA system will be able to be attached and integrated to various bioreactor systems regardless of their form factors, spanning from stirred tank bioreactors to single use bioreactors (SUB). To achieve this, LIBRA will rely on a highly multi-disciplinary consortium comprising expertise and specialization in several fields spanning photonics, surface functionalization, microfluidics, advanced packaging and assembly, artificial intelligence and bioreactor manufacturers. The exploitable results of LIBRA are expected to disrupt the current PIC-based sensing landscape, as estimated by the two business cases stemming from the project: the market revenues one year after the end of this project are expected to be €7.8 million growing to almost €59 million in 2032, and plethora of new IP and new business opportunities for the partners involved in the joint venture of LIBRA.

Coordinator

ETHNICON METSOVION POLYTECHNION
Net EU contribution
€ 686 250,00
Address
Heroon Polytechniou 9 Zographou Campus
157 80 Athina
Greece

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Region
Κεντρικός Τομέας Αθηνών Aττική Αττική
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (10)

LIONIX INTERNATIONAL BV
Netherlands
Net EU contribution
€ 790 750,00
Address
Hengelosestraat 500
7521 AN Enschede

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Region
Oost-Nederland Overijssel Twente
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
OPTAGON FOTONIKI IDIOTIKI KEFALAIOUCHIKI ETAIRIA
Greece
Net EU contribution
€ 259 375,00
Address
El. Venizelou 47
15351 Pallini, Athina

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ανατολική Αττική Aττική Αττική
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
FIBO LABS OY
Finland
Net EU contribution
€ 570 000,00
Address
Hudsson Capellankuja 1 As 9
00580 Helsinki

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
DEMCON ADVANCED MECHATRONICS ENSCHEDE B.V.
Netherlands
Net EU contribution
€ 602 805,00
Address
Institutenweg 25
7521 PH Enschede

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Oost-Nederland Overijssel Twente
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

DEMCON FOCAL BV
Netherlands
Net EU contribution
€ 102 345,00
Address
Institutenweg 25 A
7521 PH Enschede

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Region
Oost-Nederland Overijssel Twente
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
PHOSPRINT IDIOTIKI KEFALAIOUXIKIETAIREIA
Greece
Net EU contribution
€ 433 750,00
Address
Patriarchou Grigoriou E’ & Neapoleos 27, Lefkippos Technology Park, Ncsrd
153 41 Agia Paraskevi Athina

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Βόρειος Τομέας Αθηνών Aττική Αττική
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
Net EU contribution
€ 252 750,00
Address
Piazzale Aldo Moro 7
00185 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Other funding
€ 0,00
SCINUS CELL EXPANSION NETHERLANDS B.V.
Netherlands
Net EU contribution
€ 297 500,00
Address
Professor Bronkhorstlaan 10, Building 48
3723 MB Bilthoven

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Region
West-Nederland Utrecht Utrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
AARHUS UNIVERSITET
Denmark
Net EU contribution
€ 261 250,00
Address
Nordre Ringgade 1
8000 Aarhus C

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Region
Danmark Midtjylland Østjylland
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
ECOVAMED
France
Net EU contribution
€ 173 750,00
Address
13 Bis, Rue Du Pave Des Gardes
92370 Chaville

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Hauts-de-Seine
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00

Partners (1)

CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT
Switzerland
Net EU contribution
€ 0,00
Address
Rue Jaquet Droz 1
2000 Neuchatel

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Region
Schweiz/Suisse/Svizzera Espace Mittelland Neuchâtel
Activity type
Research Organisations
Other funding
€ 0,00