SECURITY PROTECTION TOOLS FOR NETWORKED MEDICAL DEVICES

Project Information

SEPTON

Grant agreement ID: 101094901

DOI

10.3030/101094901

Project closed

EC signature date 22 November 2022

Start date 1 December 2022

End date 30 November 2025

Funded under

• Health

Total cost

€ 4 897 778,75

EU contribution

€ 4 897 778,50

Coordinated by

SPACE HELLAS ANONYMI ETAIREIA SYSTIMATA KAI YPIRESIES TILEPIKOINONIONPLIROFORIKIS ASFALEIAS - IDIOTIKI EPICHEIRISI PAROCHIS YPERISION ASFA
Greece

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (7)

Project management handbook

Project managementhandbook

Legal and ethics framework -second edition

Legal and ethics framework ( second editions)

SEPTON dissemination material -first edition
Dissemination plan and communication activities report -first edition

Dissemination plan and communication activities report -first edition

SEPTON dissemination material -second edition
Updated Data Management Plan

Update Data Management Plan

Data management plan

Publications

Peer reviewed articles (9)

Fear of Missing Out: Constrained Trial of Blockchain in Supply Chain

Author(s): Roland Kromes, Tianyu Li, Maxime Bouillon, Talha Enes Güler, Victor van der Hulst, Zekeriya Erkin
Published in: MDPI Sensor, 2024, ISSN 1424-8220
Publisher: MDPI
DOI: 10.3390/S24030986

NeuroDots: From Single-Target to Brain-Network Modulation: Why and What Is Needed?

Author(s): Dirk De Ridder, Muhammad Ali Siddiqi, Justin Dauwels, Wouter A. Serdijn, Christos Strydis
Published in: Neuromodulation: Technology at the Neural Interface, ISSN 1525-1403
Publisher: Elsevier
DOI: 10.1016/J.NEUROM.2024.01.003

Quantum neural networks meet federated learning for DNA mutation prediction

Author(s): Sotirios Messinis, Ioannis Rallis, Nikolaos Temenos, Dimitrios Kalogeras, George A. Kastis, Nikolaos Doulamis, Nicholas E. Protonotarios
Published in: Computational and Structural Biotechnology Journal, Issue 30, 2026, ISSN 2001-0370
Publisher: Elsevier BV
DOI: 10.1016/J.CSBJ.2025.09.036

Differentially Private Client Selection and Resource Allocation in Federated Learning for Medical Applications Using Graph Neural Networks

Author(s): Sotirios C. Messinis, Nicholas E. Protonotarios, Nikolaos Doulamis
Published in: Sensors, Issue 24, 2025, ISSN 1424-8220
Publisher: MDPI AG
DOI: 10.3390/S24165142

Frontiers in Neuroinformatics

Author(s): R. Miedema and C. Strydis
Published in: Frontiers in Neuroinformatics, ISSN 1662-5196
Publisher: Frontiers Research Foundation
DOI: 10.3389/FNINF.2024.1330875

Neurocomputing

Author(s): Lennart P. L. Landsmeer, Max C. W. Engelen, Rene Miedema, Christos Strydis
Published in: Neurocomputing, ISSN 0925-2312
Publisher: Elsevier
DOI: 10.1016/J.NEUCOM.2024.127953

Decoupling model descriptions from execution: a modular paradigm for extensible neurosimulation with EDEN

Author(s): Sotirios Panagiotou, Rene Miedema, Dimitrios Soudris, Christos Strydis
Published in: Frontiers in Neuroinformatics, Issue 19, 2025, ISSN 1662-5196
Publisher: Frontiers Media SA
DOI: 10.3389/FNINF.2025.1572782

SHAP Interpretations of Tree and Neural Network DNS Classifiers for Analyzing DGA Family Characteristics

Author(s): Nikos Kostopoulos; Dimitris Kalogeras; Dimitris Pantazatos; Maria Grammatikou; Vasilis Maglaris
Published in: IEEE Access, Vol 11, Pp 61144-61160 (2023), 2023, ISSN 2169-3536
Publisher: IEEE Access
DOI: 10.1109/access.2023.3286313

Computers in Biology and Medicine

Author(s): S. Messinis, N. Temenos, N. E. Protonotarios, I. Rallis, D. Kalogeras, and N. Doulamis,
Published in: Computers in Biology and Medicine, ISSN 0010-4825
Publisher: Pergamon Press Ltd.
DOI: 10.1016/J.COMPBIOMED.2024.108036

Book chapters (2)

MDCG 2019-16 Guidelines: Case Study-Based Assessment and Path Forward

Author(s): Christos Androutsos, Steve Taylor, Karin Bernsmed, Andrea Neverdal Skytterholm, Gregory Epiphaniou, Nabil Moukafih, Theodoros N. Arvanitis, Sotiris Messinis, Nikos Papadakis, Marco Fruscione, Andrés Castillo, Dusko Milojevic, Dimitrios S. Karas, Nikolaos Fotos, Max Ostermann, Oscar Freyer, Stephen Gilbert, Vasilis Pezoulas, Lambros Athanasiou, George Gkois, Dimitrios I. Fotiadis
Published in: Communications in Computer and Information Science, Cybersecurity, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-94855-8_22

Threshold Multiparty Private Set Intersection via Federated Graph Neural Networks

Author(s): Sotirios Messinis, Nicholas E. Protonotarios, Dimitris Kalogeras, Nikolaos Doulamis
Published in: Communications in Computer and Information Science, Cybersecurity, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-94855-8_23

Conference proceedings (28)

A Way Forward for the MDCG 2019-16 Medical Device Security Guidance

Author(s): Taylor, S., Gilje Jaatun, M., Bernsmed, K., Androutsos, C., Frey, D., Favrin, S., ... & Katzis, K.
Published in: PETRA 2024 CYMED
Publisher: ACM
DOI: 10.1145/3652037.3663894

Memristor-Based Lightweight Encryption

Author(s): Muhammad Ali Siddiqi, Jan Andres Galvan Hernández, Anteneh Gebregiorgis, Rajendra Bishnoi, Christos Strydis, Said Hamdioui, Mottaqiallah Taouil
Published in: DSD 2023
Publisher: IEEE
DOI: 10.1109/DSD60849.2023.00092

Privacy-Preserving Data Aggregation with Public Verifiability Against Internal Adversaries

Author(s): Palazzo M., Dekker F.W., Brighente A., Conti M., Erkin Z.
Published in: 33rd USENIX Security Symposium
Publisher: USENIX Association

Synthetic Data Generation and Impact Analysisof Machine Learning Models for Enhanced Credit Card Fraud Detection

Author(s): Shareeful Islam, Spyros Papastergiou
Published in: Springer - International Conference on Artificial Intelligence Applications andInnovations(AIAI), ISSN 2193-1801
Publisher: Springer Science and Business Media Deutschland GmbH

Randomized Response and Differential Privacy

Author(s): ANDREAS IOANNIDIS ,ANTONIOS LITKE, and NIKOLAOS K. PAPADAKIS
Published in: PETRA 2024 CYMED, 2024
Publisher: ACM
DOI: 10.1145/3652037.3663902

Dataset Watermarking Using the Discrete Wavelet Transform

Author(s): M.P. Raave, D. Isler, Z. Erkin
Published in: SECRYP
Publisher: SCITEPRESS

Demo - MedGuard: Securing Medical IoT with compiler polymorphism

Author(s): Dimitris Santorinaios, Michail Alexandros Kourtis, Anna Santorinaiou, George Oikonomakis
Published in: 2024 IEEE International Workshop on Information Forensics and Security (WIFS), 2024
Publisher: IEEE
DOI: 10.1109/WIFS61860.2024.10810710

Enhancing Malware Detection through Machine Learning using XAI with SHAP Framework

Author(s): Shareeful Islam, Spyros Papastergiou
Published in: Springer - International Conference on Artificial Intelligence Applications and Innovations(AIAI), ISSN 2193-1801
Publisher: Springer Science and Business Media Deutschland GmbH

Topology-Based Reconstruction Prevention for Decentralised Learning

Author(s): F. W. Dekker, Z. Erkin, M. Conti
Published in: The 25th Privacy Enhancing Technologies Symposium
Publisher: PETs
DOI: 10.48550/ARXIV.2312.05248

Demo: MedTech Chain 2.0 Integration of Homomorphic Encryption into a Decentralized Platform for Medical Device Data Research

Author(s): Yavor Pachedzhiev, Andaç Durmaz , Ege Yarar, Ivan Markov, Sinan Önen, Roland Kromes and Zekeriya Erkin
Published in: IEEE 7th Conference on Blockchain Research & Applications for Innovative Networks and Service
Publisher: IEEE

Extending Null Embedding for Deep Neural Network (DNN) Watermarking

Author(s): K. Altınay, D. Isler, Z. Erkin
Published in: SECRYP
Publisher: SCITEPRESS

Demo: Gryphon Digital Identity Management System with Hyperledger Fabric, Compatible with Decentralized Identifiers and Verifiable Credentials

Author(s): Alessandro Neri, Iulian Onea, Matei Pânzariu, Mihai Frânculescu, Roland Kromes and Zekeriya Erkin
Published in: IEEE 7th Conference on Blockchain Research & Applications for Innovative Networks and Service
Publisher: IEEE

SEPTON Toolkit application: An overview of the security techniques used from wearable medical devices to physician’s healthcare platform.

Author(s): BAKIRIS EMMANOUIL,VICTORIA KATSAROU,NIKOS PAPADAKIS, NIKOLAOS ALAMPASIS
Published in: PETRA 2024 CYMED
Publisher: ACM

Collective Threshold Multiparty Private Set Intersection Protocols for Cyber Threat Intelligence.

Author(s): C. Guan, Z. Erkin
Published in: 16th IEEE INTERNATIONAL WORKSHOP ON INFORMATION FORENSICS AND SECURITY (WIFS) 2024
Publisher: IEEE

Oikonomos-II: A Reinforcement-Learning, Resource-Recommendation System for Cloud HPC

Author(s): J.L.F. Betting, C.I. De Zeeuw, C. Strydis
Published in: 2023 IEEE 30th International Conference on High Performance Computing, Data, and Analytics (HiPC), 2024
Publisher: IEEE
DOI: 10.1109/HIPC58850.2023.00044

NetPacketformer: Real-Time, Context-Aware Network Intrusion Detection with Transformers

Author(s): Armando Domi, Christos Zonios, Giorgos Tatsis, Anastasios Drosou, Dimitrios Tzovaras
Published in: 2025 IEEE International Conference on Cyber Security and Resilience (CSR), 2025
Publisher: IEEE
DOI: 10.1109/CSR64739.2025.11130136

A lightweight architecture for real-time neuronal-spike classification

Author(s): Siddiqi, M. A., Vrijenhoek, D., Landsmeer, L. P. L., van der Kleij, J., Gebregiorgis, A., Romano, V., Bishnoi, R., Hamdioui, S., & Strydis, C.
Published in: 21st ACM International Conference on Computing Frontiers (CF'24), ISSN 1551-7616
Publisher: ACM

Design and Implementation of Health Tracking and Monitoring System Based on IoMT technology supported by secure firmware data logging storage and wireless communication.

Author(s): Victoria Katsarou, Nick Alampasis, Nikos Papadakis, Emmanοuil Bakiris
Published in: PETRA 2024 DEMO, 2024
Publisher: ACM

Lightweight machine learning for privacy-preserving and secure networked medical devices: The SEPTON project use cases

Author(s): S. Messinis, N. E. Protonotarios, I.Tzortzis, I. Rallis, D. Kalogeras, and N. Doulamis,
Published in: PETRA 2023, 2023
DOI: 10.1145/3594806.3596562

HUMA: Heterogeneous, Ultra Low-Latency Model Accelerator for The Virtual Brain on a Versal Adaptive SoC

Author(s): Amirreza Movahedin, Lennart P. L. Landsmeer, Christos Strydis
Published in: Proceedings of the 2025 ACM/SIGDA International Symposium on Field Programmable Gate Arrays, 2025
Publisher: ACM
DOI: 10.1145/3706628.3708875

Enhancing Federated Graph Learning with Adaptive Differential Privacy

Author(s): Sotirios Messinis, Nicholas E. Protonotarios, Ioannis Rallis, Dimitrios Kalogeras, Nikolaos Doulamis
Published in: 2025 IEEE 45th International Conference on Distributed Computing Systems Workshops (ICDCSW), 2025
Publisher: IEEE
DOI: 10.1109/ICDCSW63273.2025.00103

MedTech Chain Demo: Decentralised, Secure and Privacy-preserving Platform for Medical Device Data Research^*

Author(s): Alin Petru-Rosu, Tamara Tataru, Jegor Zelenjak, Roland Kromes, Zekeriya Erkin
Published in: 2024 6th Conference on Blockchain Research & Applications for Innovative Networks and Services (BRAINS), 2024
Publisher: IEEE
DOI: 10.1109/BRAINS63024.2024.10732467

Zeekflow+: A Deep LSTM Autoencoder with Integrated Random Forest Classifier for Binary & Multi-class Classification in Network Traffic Data

Author(s): EMMANOUIL ARAPIDIS∗NIKOS TEMENOS, DIMITRIS GIAGKOS, IOANNIS K. RALLIS, DIMITRIS KALOGERAS, NIKOLAOS PAPADAKIS, ANTONIS LITKE, SOTIRIS MESSINIS
Published in: PETRA 2024 CYMED
Publisher: ACM
DOI: 10.1145/3652037.3663908

Auditable Medical Data Sharing through Recoverable Key Agreement

Author(s): van Assen J., Kromes R., Erkin Z.
Published in: IEEE 6th Conference on Blockchain Research & Applications for Innovative Networks and Services
Publisher: IEEE

Completely FROST-ed: IoT issued FROST signature for Hyperledger Fabric blockchain

Author(s): Mostafa Khattat, Roland Kromes
Published in: IEEE International Conference on Blockchain and Cryptocurrency 2024
Publisher: IEEE

IoT-Driven Security Solutions for Resource-Constrained Wearable Medical Devices

Author(s): Emmanouil Bakiris, George Oikonomakis
Published in: EICC 2025
Publisher: SPRINGER
DOI: 10.1007/978-3-031-94855-8_18

Client Selection and Resource Allocation via Graph Neural Networks for Efficient Federated Learning in Healthcare Environments.

Author(s): C. Messinis, S., Ε. Protonotarios, N., Arapidis, E., & Doulamis, N
Published in: PETRA 2024 CYMED, 2024
Publisher: ACM
DOI: 10.1145/3652037.3663906

Towards Enhanced Data Integrity and Accountability: Leveraging Blockchain Technology in Healthcare

Author(s): ATHANASIOS KOULIANOS, PANAGIOTIS PARASKEVOPOULOS, ANTONIOS LITKE, and NIKOLAOS K. PAPADAKIS
Published in: PETRA 2024 CYMED
Publisher: ACM