PROGNOSIS IMPROVEMENT OF UNPROVOKED VENOUS THROMBOEMBOLISM USING PERSONALIZED ANTICOAGULANT THERAPY

Project Information

MORPHEUS

Grant agreement ID: 101095698

DOI

10.3030/101095698

EC signature date 8 November 2023

Start date 1 December 2023

End date 30 November 2028

Funded under

• Health

Total cost

€ 9 958 833,50

EU contribution

€ 9 958 833,00

Coordinated by

CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE BREST
France

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Deliverables

Documents, reports (5)

Identified relevant socio-anthropological markers to inform TDMI tool

Transcribe and analyse all interviews at the national and international levels, to extract relevant information for the multicomponent tool development. Analyses will be ready at the end of M16.

Qualitative studies report on statut of posting results

Synthetic report on qualitative studies to inform the multicomponent tool development

Selection of relevant biomarkers – Delphi1

Identification of candidate biomarkers (for recurrentt VTE and bleeding) from systematic literature review/ Selection via Delphi technique including a large panel of expert physicians in the field, social scientist in order to select most relevant biomarkers that should be included in the TDMI tool.

Papers submitted on patient’s preference and experience

submission of the results on socio-anthropological markers that will inform TDMI tool in per-reviewed journals

Derived scores from merged cohorts

Derivation of scores an exhaustive collection of clinical, biological and imaging data including biobank and imaging data from merged cohorts. Analyses includes predictor-outcomes associations, derivation of risk stratification models, calibration, adjustment for optimism and internal validation of the models, and elaboration of clinical decision model (decision rule)

Other (1)

"Qualitative studies midterm recruitment report for the ""ANTHROPO-MORPHEUS"" study"

"Conduct a multicentre semi-directive interview study (""Anthropo-Morpheus study"") in France, Spain and Denmark that includes 45 interviews with patients (15 in each country) and 15 interviews with practitioners (5 in each country)/ report at midterm recruitment will be provided (ie, on 25 interviews) ."

Websites, patent fillings, videos etc. (1)

Project website and logo

Design the logo and graphical chart to generate visual identity for the project/Set up the public internet website as the main dissemination and communication tool