Repurposing of CAST Systems as Next-Generation Tools for Genome Engineering of Mammalian Cells

Project Information

INTETOOLS

Grant agreement ID: 101096548

DOI

10.3030/101096548

EC signature date 3 July 2023

Start date 1 November 2023

End date 31 October 2028

Funded under

• European Research Council (ERC)

Total cost

€ 2 475 491,00

EU contribution

€ 2 475 491,00

Coordinated by

KOBENHAVNS UNIVERSITET
Denmark

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Retron-Eco1 assembles NAD+-hydrolyzing filaments that provide immunity against bacteriophages

Author(s): Arturo Carabias, Sarah Camara-Wilpert, Mario Rodríguez Mestre, Blanca Lopéz-Méndez, Ivo A. Hendriks, Ruiliang Zhao, Tillmann Pape, Anders Fuglsang, Sean Hoi-Ching Luk, Michael L. Nielsen, Rafael Pinilla-Redondo, Guillermo Montoya
Published in: Molecular Cell, Issue 84, 2025, ISSN 1097-2765
Publisher: Elsevier BV
DOI: 10.1016/J.MOLCEL.2024.05.001

Conformational landscape of the type V-K CRISPR-associated transposon integration assembly

Author(s): Francisco Tenjo-Castaño, Nicholas Sofos, Luisa S. Stutzke, Piero Temperini, Anders Fuglsang, Tillmann Pape, Pablo Mesa, Guillermo Montoya
Published in: Molecular Cell, Issue 84, 2025, ISSN 1097-2765
Publisher: Elsevier BV
DOI: 10.1016/J.MOLCEL.2024.05.005

Unlocking the potential of CRISPR-associated transposons: from structural to functional insights

Author(s): Francisco Tenjo-Castaño, Sweta Suman Rout, Sanjay Dey, Guillermo Montoya
Published in: Trends in Genetics, Issue 41, 2025, ISSN 0168-9525
Publisher: Elsevier BV
DOI: 10.1016/J.TIG.2025.04.005

NAD reloaded: Hacking bacterial defenses

Author(s): Arturo Carabias, Guillermo Montoya
Published in: Cell Chemical Biology, Issue 31, 2024, ISSN 2451-9456
Publisher: Elsevier BV
DOI: 10.1016/J.CHEMBIOL.2024.10.012

The fork protection complex promotes parental histone recycling and epigenetic memory

Author(s): Sebastian Jespersen Charlton, Valentin Flury, Yutaka Kanoh, Aitana Victoria Genzor, Leonie Kollenstart, Wantong Ao, Peter Brøgger, Melanie Bianca Weisser, Marek Adamus, Nicolas Alcaraz, Charlotte M. Delvaux de Fenffe, Francesca Mattiroli, Guillermo Montoya, Hisao Masai, Anja Groth, Geneviève Thon
Published in: Cell, Issue 187, 2024, ISSN 0092-8674
Publisher: Elsevier BV
DOI: 10.1016/J.CELL.2024.07.017