Breaking resistance of pathogenic bacteria by chemical dysregulation

Project Information

breakingBAC

Grant agreement ID: 101096911

DOI

10.3030/101096911

EC signature date 5 May 2023

Start date 1 September 2023

End date 31 August 2028

Funded under

• European Research Council (ERC)

Total cost

€ 2 499 785,00

EU contribution

€ 2 499 785,00

Coordinated by

TECHNISCHE UNIVERSITAET MUENCHEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Journal of Cheminformatics

Author(s): Maximilian G. Schuh; Davide Boldini; Annkathrin I. Bohne; Stephan A. Sieber
Published in: Journal of Cheminformatics, 2025, ISSN 1758-2946
Publisher: BMC Springer
DOI: 10.48550/ARXIV.2408.00040

Screening Privileged Alkyl Guanidinium Motifs under Host-Mimicking Conditions Reveals a Novel Antibiotic with an Unconventional Mode of Action

Author(s): Dominik Schum; Franziska A. V. Elsen; Stuart Ruddell; Kenji Schorpp; Howard Junca; Mathias Müsken; Shu-Yu Chen; Michaela K. Fiedler; Thomas Pickl; Dietmar H. Pieper; Kamyar Hadian; Martin Zacharias; Stephan A. Sieber
Published in: JACS Au, 2024, ISSN 2691-3704
Publisher: ACS
DOI: 10.1021/JACSAU.4C00449

Generative deep learning pipeline yields potent Gram-negative antibiotics

Author(s): Martin F. Köllen; Maximilian G. Schuh; Robin Kretschmer; Junhong Chen; Annkathrin I. Bohne; Dominik P. Halter; Stephan A. Sieber
Published in: JACS_AU, 2025, ISSN 2691-3704
Publisher: ACS
DOI: 10.1021/JACSAU.5C00602

Journal of Chemical Information and Modeling

Author(s): Maximilian G. Schuh; Davide Boldini; Stephan A. Sieber
Published in: Journal of Chemical Information and Modeling, 2024, ISSN 1549-9596
Publisher: ACS
DOI: 10.1021/ACS.JCIM.4C00765

Journal of Cheminformatics

Author(s): Joshua Hesse; Davide Boldini; Stephan A. Sieber
Published in: Journal of Chemical Information and Modeling, 2024, ISSN 1758-2946
Publisher: BMC Springer
DOI: 10.1021/ACS.JCIM.4C01547

Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery

Author(s): Davide Boldini; Lukas Friedrich; Daniel Kuhn; Stephan Sieber
Published in: ACS Central Science, 2023, ISSN 2374-7951
Publisher: ACS
DOI: 10.26434/CHEMRXIV-2023-ZRGKP