Principles of endogenous and therapeutic mRNA turnover in vivo

Project Information

ViveRNA

Grant agreement ID: 101097317

DOI

10.3030/101097317

EC signature date 5 May 2023

Start date 1 November 2023

End date 31 October 2028

Funded under

• European Research Council (ERC)

Total cost

€ 2 499 875,00

EU contribution

€ 2 499 875,00

Coordinated by

MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ W WARSZAWIE
Poland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Nature

Author(s): Paweł S. Krawczyk; Michał Mazur; Wiktoria Orzeł; Olga Gewartowska; Sebastian Jeleń; Wiktor Antczak; Karolina Kasztelan; Aleksandra Brouze; Katarzyna Matylla-Kulińska; Natalia Gumińska; Bartosz T
Published in: Nature, 2025, ISSN 0028-0836
Publisher: Springer Nature
DOI: 10.1038/S41586-025-08842-1

Excretory gland cell and NSPC genes in <i>C. elegans</i>: investigating their physiological roles

Author(s): Zuzanna Mackiewicz, Vladyslava Liudkovska, Andrzej Dziembowski
Published in: GENETICS, Issue 231, 2025, ISSN 1943-2631
Publisher: Oxford University Press (OUP)
DOI: 10.1093/GENETICS/IYAF125

Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines

Author(s): Paweł S. Krawczyk, Michał Mazur, Wiktoria Orzeł, Olga Gewartowska, Sebastian Jeleń, Wiktor Antczak, Karolina Kasztelan, Aleksandra Brouze, Katarzyna Matylla-Kulińska, Natalia Gumińska, Bartosz Tarkowski, Ewelina P. Owczarek, Kamila Affek, Paweł Turowski, Agnieszka Tudek, Małgorzata Sroka, Tomasz Śpiewla, Monika Kusio-Kobiałka, Aleksandra Wesołowska, Dominika Nowis, Jakub Golab, Joanna Kowalska, Jacek Jemielity, Andrzej Dziembowski, Seweryn Mroczek
Published in: Nature, Issue 641, 2025, ISSN 0028-0836
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41586-025-08842-1

TENT-5 polyadenylates and regulates male-specific transcripts in <i>Caenorhabditis elegans</i>

Author(s): Zuzanna Mackiewicz, Vladyslava Liudkovska, Andrzej Dziembowski
Published in: G3: Genes, Genomes, Genetics, Issue 16, 2026, ISSN 2160-1836
Publisher: Oxford University Press (OUP)
DOI: 10.1093/G3JOURNAL/JKAG058

Modeling of mRNA deadenylation rates reveal a complex relationship between mRNA deadenylation and decay

Author(s): Agnieszka Czarnocka-Cieciura, Jarosław Poznański, Matti Turtola, Rafał Tomecki, Paweł S Krawczyk, Seweryn Mroczek, Wiktoria Orzeł, Upasana Saha, Torben Heick Jensen, Andrzej Dziembowski, Agnieszka Tudek
Published in: The EMBO Journal, Issue 43, 2024, ISSN 1460-2075
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S44318-024-00258-3

Comprehensive analysis of poly(A) tails in mouse testes and ovaries using Nanopore Direct RNA Sequencing

Author(s): Agnieszka Czarnocka-Cieciura; Michał Brouze; Natalia Gumińska; Seweryn Mroczek; Olga Gewartowska; Paweł S. Krawczyk; Andrzej Dziembowski
Published in: Scientific Data, 2025, ISSN 2052-4463
Publisher: Nature-Springher
DOI: 10.1038/S41597-024-04226-8

Direct profiling of non-adenosines in poly(A) tails of endogenous and therapeutic mRNAs with Ninetails

Author(s): Natalia Gumińska, Katarzyna Matylla-Kulińska, Paweł S. Krawczyk, Michał Maj, Wiktoria Orzeł, Zuzanna Mackiewicz, Aleksandra Brouze, Seweryn Mroczek, Andrzej Dziembowski
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-57787-6

EMBO Journal

Author(s): Agnieszka Czarnocka-Cieciura; Jarosław Poznański; Matti Turtola; Rafał Tomecki; Paweł S Krawczyk; Seweryn Mroczek; Wiktoria Orzeł; Upasana Saha; Torben Heick Jensen; Andrzej Dziembowski; Agnieszka Tudek
Published in: The EMBO Journal, 2024, ISSN 0261-4189
Publisher: Springer Nature
DOI: 10.1038/S44318-024-00258-3

Nature Communications

Author(s): Natalia Gumińska; Katarzyna Matylla-Kulińska; Paweł S. Krawczyk; Michał Maj; Wiktoria Orzeł; Zuzanna Mackiewicz; Aleksandra Brouze; Seweryn Mroczek; Andrzej Dziembowski
Published in: Nature Communications, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/S41467-025-57787-6

Polyadenylation landscape of in vivo long-term potentiation in the rat brain

Author(s): Natalia Gumińska, Francois P. Pauzin, Bożena Kuźniewska, Jacek Miłek, Patrycja Wardaszka-Pianka, Paweł S. Krawczyk, Seweryn Mroczek, Sebastian Jeleń, Patrick U. Pagenhart, Clive R. Bramham, Andrzej Dziembowski, Magdalena Dziembowska
Published in: RNA, Issue 31, 2025, ISSN 1355-8382
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1261/RNA.080485.125