Project description
Innovative at-home skin monitoring device
Skin conditions, such as acne or atopic dermatitis, create a high economic and psychological burden on society. They are a result of environmental and hygienic factors, as well as genetics, while diagnosis involves visual inspection, dermoscopic examination and in some cases skin biopsy. Being able to non-invasively monitor skin status would facilitate prompt detection and treatment of dermatological conditions. Funded by the European Innovation Council, the SKINDEV project will introduce technological innovations in a smart skin device that can be used at home to monitor the condition of the skin. The technological innovations will be based on key aspects of skin microbes and generated knowledge regarding disease pathophysiology.
Objective
The long-term vision and ambition of the SKINDEV consortium is to complement the human skin microbiome with Smart Skin Microbial Devices (SSMDs) in atopic dermatitis (AD) patients and other dermatological conditions as a new non-invasive system for future treatment and monitoring of disease gearing up towards preventive care. This idea and new technology are groundbreaking and radical.
SKINDEV aims to make SSMDs generally applicable through innovative technologies like sensing applications in wearables and cameras providing at-home on-demand skin health information. SSMDs will be ideal for early detection and intervention of health hazards.
In this Pathfinder project the focus is on interaction at three steppingstones (SS), towards a prototype SSMD with proof-of-concept for the coupling of sensing and actuation in Cutibacterium acnes (C. acnes) for AD-related inflammatory processes:
SS1. Systems engineering to create a multi-scale computational model of AD pathophysiology;
SS2. Genetic engineering to create sensing and actuation circuits in C. acnes;
SS3. Tissue engineering to create a high throughput skin organoid platform for AD.
A priority of SKINDEV is to translate technological innovations into proof-of-concept novel devices. SKINDEV is expected to invent such new technologies to i) genetically modify skin microbes, ii) create sensing modules and actuators, and iii) develop pre-clinical skin organoids and computational models for host-microbe interactions. The work plan implements an efficient design, build, test and learn cycle to accelerate the achievement of sensing and actuating performance fulfilling relevant physiological roles.
Successful achievement of these ambitious goals requires highly integrated interdisciplinary collaborations by scientists working at the forefront of relevant disciplines.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsoptical sensors
- medical and health sciencesbasic medicinephysiologypathophysiology
- natural sciencesbiological sciencesmicrobiology
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Programme(s)
- HORIZON.3.1 - The European Innovation Council (EIC) Main Programme
Call for proposal
(opens in new window) HORIZON-EIC-2022-PATHFINDEROPEN-01
See other projects for this callFunding Scheme
HORIZON-EIC - HORIZON EIC GrantsCoordinator
08002 Barcelona
Spain