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CRISPR Point-of-Care Diagnostics

Project description

Advancing the diagnostic potential of CRISPR-Cas

The CRISPR-Cas technology allows for genome editing and diagnostics. The bacterial CRISPR-Cas defence mechanism generally uses a short RNA molecule that guides a Cas effector protein (or protein complex) to a matching target sequence. Several CRISPR-Cas types have been characterised in great detail. With respect to diagnostic applications, the type III CRISPR-Cas system has great potential. Although a recently established multistep diagnostic approach sparked a lot of interest, there is room for improvement. Funded by the European Research Council, the SCOPE project introduces a thermostable RNA polymerase to streamline the entire process into a single step. The project aims to provide proof of concept of the technical feasibility of this proposition to allow the diagnosis of chronic obstructive pulmonary disease.


Net EU contribution
€ 150 000,00
Droevendaalsesteeg 4
6708 PB Wageningen

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Oost-Nederland Gelderland Veluwe
Activity type
Higher or Secondary Education Establishments
Other funding
No data