Project description
Protecting potatoes against pathogens
Potatoes are crucial for global food security, yet they face serious threats from various pathogens. Poland, the second-largest producer in the EU, harvests around nine million tonnes annually, underscoring the importance of protecting this vital crop. The lack of resistant potato varieties and the increasing resistance of pathogens to fungicides heighten the urgency. Understanding the factors behind natural potato immunity is essential. Supported by the Marie Skłodowska-Curie Actions programme, the ONGUARD project explores the roles of nitric oxide (NO) and nitroxyl (HNO) in enhancing potato defence against Phytophthora infestans, the cause of late blight disease. Overall, it seeks to reveal how HNO influences plant defence mechanisms, potentially improving resilience and safeguarding potato yields.
Objective
Potato (Solanum tuberosum L.) is one of the world’s most important crops for human consumption, thus it is an integral part of the world's food supply. Poland is the world's 8th largest producer (2nd in the EU), with 9 million tons annually. Potato is susceptible to a wide range of pathogenic organisms, which can cause severe quality and yield losses worldwide. Given the absence of cultivars resistant to pathogens and the immunization of pathogen isolates to successive fungicides, any attempt to understand and strengthen the knowledge of factors related to natural potato immunity is extremely important.
In light of this, it is well documented that nitric oxide (•NO) is a key element involved in pathogen recognition as well as activation of local and systemic plant defense signaling activities and pathways. Moreover, the interdisciplinary group proposing this plan recently reported endogenous production of HNO (nitroxyl) in plant tissues (Arabidopsis thaliana) for the first time, and points toward a novel regulatory role. Under physiological conditions, HNO concentration in plant cells is in the nanomolar range. The ubiquitous HNO bioavailability allows it to support or compete with •NO signaling, depending on the local redox environment (shifts with stress or senescence). Finally, we showed that HNO formation is an early reductive stress-related response.
Taking all this into account, this proposal will focus on the real-time detection and visualization of simultaneously endogenous HNO and NO in leaves of the important crop plant challenge inoculated with vr/avr Phytophthora infestans, a cause of late blight disease. Moreover, it will be an important issue to answer the question of whether and to what degree the HNO presence in cells modifies the plant's defense responses. The hypothesis is that HNO is generated during potato - P. infestans interaction and can act as a functional signal molecule favoring redox changes towards effective defense responses in potato.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine immunology immunisation
- agricultural sciences agriculture, forestry, and fisheries agriculture
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
61 712 POZNAN
Poland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.