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The first wide range flow sensor to unlock microfluidic cell analyses for preclinical studies

Objective

There is a critical need to improve the diagnosis, drug discovery and development pipeline to increase the success rate of new therapeutics (as low as 3.4% for cancer drugs) and provide earlier detection and treatment. Microfluidic cell-based assays and analyses are one of the most promising strategies, supported by direct feedback from industry and regulatory agencies. Integrated microscale fluidics adds an extra dimension to in vitro cell cultures and is an enabling technology of single cell analyses and nanotherapies. However, the main limitations with these platforms expressed by our clients from academia and industry are their inability to measure and control flow rate over a wide enough range (100-times too narrow), imprecision and failure to detect sensor drift that leads to experimental error. Our GALILEO flow sensor innovation demonstrates the technical ability to address these pressing requirements for microfluidic cell assays and analyses. This proposal will advance the proof of concept to a viable demonstrator of the technology for beta testing.
The timing is ideal for our solution: expressed end user demand is high and legislative bodies have voted to reduce animal testing by 2035. GALILEO has strong competitive advantage in the microfluidic flow sensor market with a SAM of 535 mil EUR/year, increasing with the growth of next-generation sequencing and genomic medicine. Elvesys is an entrepreneur-led microfluidics instrument company with demonstrated success in the development and commercialisation of 15 instruments for microfluidic flow control, and the generation of 10 growing spin-offs in the last 11 years. Our end user feedback and iterative testing approach to innovation puts us in a position of strength to execute an optimal product-market fit, targeting market creation. We have the proven technical expertise to deliver on GALILEO performance, and the market contact breadth to disseminate, exploit and communicate the technology to all stakeholders.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-EIC - HORIZON EIC Grants

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-EIC-2022-TRANSITION-01

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Coordinator

MICROFLUIDICS INNOVATION CENTER
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 272 263,18
Address
172 RUE DE CHARONNE
75011 PARIS
France

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 272 263,18

Participants (1)

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