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A Paradigm Shift in Health Monitoring with Electrospun Enzymatic Neomaterials

Project description

Innovative technology for smart wound dressings

Chronic non-healing wounds pose a significant public health challenge: an innovative approach is needed to enhance patient quality of life while minimising the impact on healthcare resources and costs. Currently, we lack of available smart bandages; a reliable inspection method is still being developed. The EU-funded WOUNDSENS project aims to address this gap by integrating wearable biosensors into wound dressings. This approach not only enhances comfort but also facilitates seamless integration into standard manufacturing processes, thereby creating a groundbreaking technology for smart wound dressings. The project involves the use of novel hollow fibres with radial bio-signalling based on engineered enzymes, innovative electrochemical materials with advancements in conductive material, and enzyme engineering for a new family of detection biocatalysts.

Objective

Global healthcare associated with chronic non-healing wounds can be considered a main public health problem as affects up to 2% of the world population. A novel approach is needed mainly to support the quality of life of the people suffering from this silent epidemic and additionally, alleviate the impact in costs and resources for the healthcare system. Up to date, no smart bandages have made it to the real market and research state is still going on for a reliable and sensitive inspection method. The main goal of WOUNDSENS project is to lead the development of a novel generation of wearable biosensors with a synergy of technological breakthroughs in transversal fields of knowledge. Sensor elements, for the first time, will directly become a compatible part of the wound dressing material itself resulting in enhanced wearing comfort and operability. Accordingly, they will be integratable into manufacturers' existing standard processes (suturing, embroidery, roll-to-roll). Our proposal presents a parading shift in smart wound dressings constructed on novel hollow fibers with radial bio-signaling based on engineered novel enzymes. WOUNDSENS presents a leading-edge new technology with the design and development of innovative electrochemical materials with step forward advances in CONDUCTIVE MATERIAL, the development of electrospun neofibers and processes with leading edge methodologies on ELECTROSPINNING and the ENZYME ENGINEERING of a new family of detection biocatalysts (resurrected and extant enzymes) to secure a sensitive and reliable signal. WOUNDSENS proposal accepts the challenge of pushing forward the new technological platform to design a new concept in continuous wound control and monitoring improving the life of millions of people.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-EIC - HORIZON EIC Grants

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Call for proposal

(opens in new window) HORIZON-EIC-2022-PATHFINDERCHALLENGES-01

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Coordinator

EVOENZYME SL
Net EU contribution
€ 1 269 300,00
Address
CALLE GRECIA NR 80 PUERTA 4 VALDEMORO
28341 Madrid
Spain
SME
Yes
Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost
€ 1 269 300,00

Participants (3)