Project description
Development of next-generation vascular grafts
Cardiovascular diseases are associated with blockage of blood vessels. Currently, grafts for replacing or bypassing blocked vessels have high failure rate due to thrombosis or infection. The ideal vascular grafts would monitor their performance and transfer data to initiate actions to avoid graft failure. The EU-funded Blood2Power project aims to contribute to a paradigm shift by enabling energy harvesting from the body to power the next-generation vascular graft, the iGraft. The objective is to develop triboelectric nanogenerators (TENGs), converting body mechanical energy into electrical energy. A miniaturised ultra-low energy consumption power management unit has to be coupled to the vascular graft, collecting and wirelessly transmitting TENG signals to an external electronic device, such as a smartphone or watch.
Objective
Cardiovascular diseases (CVD) are the leading cause of death globally, taking 18.6M lives/yr. Most CVD are associated with blockage ofblood vessels. grafts play a vital role, replacing/bypassing these vessels, but have failure rates up to 50% due to thrombosis or infection. Vascular grafts of the future would ideally sense and monitor its performance, and telemetrically emit data/alerts to healthcare system so that medical actions can be performed to avoid graft failure. IoMTs has taken its first steps, but is still far from full potential/development, especially in implantable systems which are limited by the use of batteries to power them.
The BLOOD2POWER project AIMS to contribute to this paradigm shift by proposing the development of a NEW WAY TO HARVEST ENERGY FROM THE BODY, and using it to create the next generation vascular grafts: the iGraft.To achieve this PIONEER technology, new triboelectric nanogenerators (TENG) will be developed, converting mechanical energy from the body into electrical energy. A miniaturized ultra-low energy consumption power management unit will be developed and coupled to the vascular graft together with a wireless system, allowing to store generated energy, and collect and wirelessly transmit TENG outputs to an external electronic device (e.g. smartphone/watch). These systems will be validated in vitro and in vivo.
Driven by these challenges, this international team led by a young researcher gathers renown institutions and researchers with unique and complementary backgrounds in biomaterials, energy harvesting, electronics and medicine.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine angiology vascular diseases
- engineering and technology industrial biotechnology biomaterials
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2022-PATHFINDERCHALLENGES-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
4200-135 PORTO
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.