Objective
Bacterial viruses, phages, are ubiquitous and most numerous entities in the biosphere. Development of sequencing techniques has increased our understanding on the diversity of phages that have not been isolated due to lack of cultivable hosts and/or suitable isolation methods. While sequence data enables a better view to the viral diversity, at the same time lack of functional data and biological connection increases. Recently, different studies have found megaphages (mainly phages with a genome over 600 kbp) by assembling metagenomes from various environmental samples. However, no such isolates have been obtained thus far meaning that their characteristics and host interactions are completely unknown. In this ERC project, I will enlighten the life of giant phages, the term I coined for both jumbo and megaphages. I will achieve this by using the first megaphage isolates that I have isolated from boreal freshwaters. During the project, evidence on the megaphage structure, the host interactions and symbiotic relationship with host will be provided. Using a unique set of different phage sizes infecting the same host I will determine the size correlation to different life history traits. I will provide insight to the mutualistic relationship between bacteria and their viruses and reveal new mechanisms behind phage competition. I will also determine the environmental preferences for the megaphage emergence and abundance in boreal freshwaters. In this proposal, I aim to understand How, Where and When megaphages are isolated. Consequently, results will aid in understanding the role of megaphages in other environments such as gut microbiome and potentially provide avenues for developing new genetic tools. This project will open new understanding for microbial ecology and especially phage ecology and the project will create a new field of study under phage biology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences microbiology virology
- natural sciences biological sciences ecology
- natural sciences earth and related environmental sciences atmospheric sciences meteorology biosphera
- natural sciences biological sciences genetics genomes
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2023-STG
See all projects funded under this callHost institution
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
40100 Jyvaskyla
Finland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.