A Direct Sensorimotor Connection with the Spared Neural Code of Movement to Regain Motor Function

Project Information

GRASPAGAIN

Grant agreement ID: 101118089

DOI

10.3030/101118089

EC signature date 17 October 2023

Start date 1 January 2024

End date 31 December 2028

Funded under

• European Research Council (ERC)

Total cost

€ 1 495 271,00

EU contribution

€ 1 495 271,00

Coordinated by

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

Research Data management

Publications

Peer reviewed articles (14)

Antagonism of 5‐HT₂ receptors attenuates self‐sustained firing of human motor units

Author(s): Benjamin I. Goodlich, Gregory E. P. Pearcey, Alessandro Del Vecchio, Sean A. Horan, Justin J. Kavanagh
Published in: The Journal of Physiology, Issue 602, 2024, ISSN 0022-3751
Publisher: Wiley
DOI: 10.1113/JP285867

Changes in neural drive after strength training are better estimated from absolute than normalized EMG amplitude

Author(s): Alessandro Del Vecchio, Andrea Casolo, Roger Maro Enoka, Dario Farina
Published in: Journal of Applied Physiology, Issue 140, 2026, ISSN 8750-7587
Publisher: American Physiological Society
DOI: 10.1152/JAPPLPHYSIOL.00810.2024

NeuroNella: Automatic identification of neural activity from multielectrode arrays with blind source separation

Author(s): C Germer, D Farina, S N Baker, A Del Vecchio
Published in: Journal of Neural Engineering, Issue 22, 2025, ISSN 1741-2560
Publisher: IOP Publishing
DOI: 10.1088/1741-2552/ADC5A4

Identification of Spared and Proportionally Controllable Hand Motor Dimensions in Motor Complete Spinal Cord Injuries Using Latent Manifold Analysis

Author(s): Raul C Sîmpetru; Daniela Souza de Oliveira; Matthias Ponfick; Alessandro Del Vecchio
Published in: IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2024, ISSN 1558-0210
Publisher: IEEE
DOI: 10.1101/2024.05.28.24307964

Non-Invasive Neural Interfacing for Tetraplegic Individuals Using Residual Motor Neuron Activity Decoded at the Forearm or Wrist

Author(s): Xingchen Yang, Daniela Souza de Oliveira, Dominik I. Braun, Matthias Ponfick, Dario Farina, Alessandro Del Vecchio
Published in: IEEE Journal of Biomedical and Health Informatics, Issue 29, 2025, ISSN 2168-2194
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.1109/JBHI.2025.3556496

MyoGestic: EMG interfacing framework for decoding multiple spared motor dimensions in individuals with neural lesions

Author(s): Raul C. Sîmpetru; Dominik I. Braun; Arndt U. Simon; Michael März; Vlad Cnejevici; Daniela Souza de Oliveira; Nico Weber; Jonas Walter; Jörg Franke; Daniel Höglinger; Cosima Prahm; Matthias Ponfick; Alessandro Del Vecchio
Published in: Science Advances, 2025, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/SCIADV.ADS9150

A direct spinal cord–computer interface enables the control of the paralysed hand in spinal cord injury

Author(s): Oliveira, Daniela Souza; Ponfick, Matthias; Braun, Dominik I; Osswald, Marius; Sierotowicz, Marek; Chatterjee, Satyaki; Weber, Douglas; Eskofier, Bjoern; Castellini, Claudio; Farina, Dario; Kinfe, Thomas Mehari; Del Vecchio, Alessandro
Published in: Brain, 2024, ISSN 1460-2156
Publisher: Oxford University Press
DOI: 10.1093/BRAIN/AWAE088

The discharge characteristics of motor units innervating functionally paralyzed muscles

Author(s): Daniela Souza De Oliveira; Marco Carbonaro; Brent James Raiteri; Alberto Botter; Matthias Ponfick; Alessandro Del Vecchio
Published in: Journal of Neurophysiology, 2025, ISSN 1522-1598
Publisher: American Physiological Society
DOI: 10.1152/JN.00389.2024

Simultaneous Estimation of Digit Tip Forces and Hand Postures in a Simulated Real-Life Condition With High-Density Electromyography and Deep Learning

Author(s): Farnaz Rahimi, Mohammad Ali Badamchizadeh, Sehraneh Ghaemi, Alessandro Del Vecchio
Published in: IEEE Journal of Biomedical and Health Informatics, Issue 28, 2024, ISSN 2168-2194
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.1109/JBHI.2024.3350239

Unsupervised neural decoding of signals recorded by thin-film electrode arrays implanted in muscles using autoencoding with a physiologically derived optimisation criterion

Author(s): Kenneth MacSporran Mayer, Alessandro Del Vecchio, Bjoern M. Eskofier, Dario Farina
Published in: Biomedical Signal Processing and Control, Issue 86, 2023, ISSN 1746-8094
Publisher: Elsevier BV
DOI: 10.1016/J.BSPC.2023.105178

Task-specific motor units in the extrinsic hand muscles control single- and multidigit tasks of the human hand

Author(s): Marius Oßwald, Andre L. Cakici, Daniela Souza de Oliveira, Dominik I. Braun, Dario Farina, Alessandro Del Vecchio
Published in: Journal of Applied Physiology, Issue 138, 2025, ISSN 8750-7587
Publisher: American Physiological Society
DOI: 10.1152/JAPPLPHYSIOL.00911.2024

Neuroplastic alterations in common synaptic inputs and synergistic motor unit clusters controlling the vastii muscles of individuals with ACL reconstruction

Author(s): Stefano Nuccio, Carina M. Germer, Andrea Casolo, Riccardo Borzuola, Luciana Labanca, Jacopo E. Rocchi, Pier Paolo Mariani, Francesco Felici, Dario Farina, Deborah Falla, Andrea Macaluso, Paola Sbriccoli, Alessandro Del Vecchio
Published in: Journal of Applied Physiology, Issue 137, 2024, ISSN 8750-7587
Publisher: American Physiological Society
DOI: 10.1152/JAPPLPHYSIOL.00056.2024

Specificity of early motor unit adaptations with resistive exercise training

Author(s): Alessandro Del Vecchio, Roger Maro Enoka, Dario Farina
Published in: The Journal of Physiology, Issue 602, 2024, ISSN 0022-3751
Publisher: Wiley
DOI: 10.1113/JP282560

Greater motor unit discharge rate during rapid contractions in chronically strength-trained individuals

Author(s): Jakob Škarabot, Andrea Casolo, Thomas G. Balshaw, Sumiaki Maeo, Marcel Bahia Lanza, Aleš Holobar, Dario Farina, Jonathan P. Folland, Alessandro Del Vecchio
Published in: Journal of Neurophysiology, Issue 132, 2024, ISSN 0022-3077
Publisher: American Physiological Society
DOI: 10.1152/JN.00017.2024