Molecular Dynamic of Neurons during C. elegans Lifespan

Project Information

NERVSPAN

Grant agreement ID: 101119745

DOI

10.3030/101119745

EC signature date 13 July 2023

Start date 1 September 2023

End date 31 August 2027

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 748 232,80

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data sets, microdata, etc (10)

High-throughput assay for neuronal function
Optimized cell-dissociation protocol
Ninein function as a microtuble organizer
Correlate ion channel expression and protein content
Time-lapse RNAseq and PDA transdifferentiation
Sex-specific neuronal RNA-seq
Proteomics of neuronal polarity regulators
Identification of the proteome of gap junctions
Identify dimorphic post-translational regulation
10x expansion microscopy for C. elegans

To test various microtubule modification antibodies commonly used in mammalian systems we will need to adapt the method to nematode samples.

Other (3)

Implementation meeting

Implementation meeting.

Training workshops
Kick-off meeting

Websites, patent fillings, videos etc. (1)

Website

Project website

Documents, reports (1)

Training Actions Program

Complete Training Workshops and Meeting Schedule

Publications

Peer reviewed articles (1)

Decoding sexual dimorphism of the sex-shared nervous system at single-neuron resolution

Author(s): Rizwanul Haque, Hagar Setty, Ramiro Lorenzo, Gil Stelzer, Ron Rotkopf, Yehuda Salzberg, Gal Goldman, Sandeep Kumar, Shiraz Nir Halber, Andrew M. Leifer, Elad Schneidman, Patrick Laurent, Meital Oren-S
Published in: 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.12.27.630541