Project description
Quantitative cognitive testing for Parkinson’s patients
Parkinson’s disease is primarily known for its motor symptoms, but over 90 % of patients also experience cognitive impairments that affect learning, memory, and decision-making. Current treatments mainly target motor symptoms and provide limited improvement in cognitive functions. Addressing cognitive symptoms could greatly enhance patients’ quality of life. The ERC-funded ParSyncR project aims to use a behavioural test of fine decision-making, combined with electroencephalography and electromyography measurements, to quantitatively assess cognitive function. This Quantitative Cognitive Testing (QCT) approach can improve Parkinson’s disease therapies, support the development of telemedicine solutions, and reduce hospital visits and patient-doctor interactions. The project will validate equipment, conduct proof-of-concept experiments, strengthen intellectual property protection, and explore commercialisation strategies.
Objective
Parkinson’s disease is dominated by motor symptoms such as tremor, bradykinesia and postural instability. However, over 90% of all patients develop cognitive impairment including deterioration of learning, memory and decision making. Current treatments focus on motor symptoms and offer at best moderate improvement of cognitive functions. Alleviating cognitive symptoms could dramatically increase quality of life of patients. Therefore, we propose to apply a behavioral test of fine decision making combined with electroencephalography and electromyography measurements to quantitatively assess complex aspects of cognitive function, including inhibitory control, learning by reinforcement and decision making under conflict. This Quantitative Cognitive Testing (QCT) can be employed to improve Parkinson’s disease therapy based on regular feedback. Moreover, the method can be extended to other domains of neurodegenerative dementias. We foresee that the application of QCT can facilitate the development of telemedicine packages, thus reducing hospital visits and patient-doctor contacts. Under this PoC, we propose to validate equipment we developed de novo, conduct proof of concept experiments, extend IPR protection, and explore commercialization strategies. We believe that QCT can help achieve the best possible cognitive function, which would improve the quality of life of patients and their families. It could also reduce disease-related cost burden on health care systems and society, making it appealing to health providers.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2023-POC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1083 BUDAPEST
Hungary
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.