Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques
(opens in new window)
Author(s):
Katyayani Sukhavasi, Giuseppe Mocci, Lijiang Ma, Chani J. Hodonsky, Ernest Diez Benevante, Lars Muhl, Jianping Liu, Sonja Gustafsson, Byambajav Buyandelger, Simon Koplev, Urban Lendahl, Michael Vanlandewijck, Prosanta Singha, Tiit Örd, Mustafa Beter, Ilakya Selvarajan, Johanna P. Laakkonen, Marika Väli, Hester M. den Ruijter, Mete Civelek, Ke Hao, Arno Ruusalepp, Christer Betsholtz, Heli Järve, Jason C. Kovacic, Clint L. Miller, Casey Romanoski, Minna U. Kaikkonen, Johan L. M. Björkegren
Published in:
Nature Cardiovascular Research, Issue 4, 2025, ISSN 2731-0590
Publisher:
Springer Science and Business Media LLC
DOI:
10.1038/S44161-025-00628-Y
Decreased degree of adipocyte differentiation in visceral adipose tissue contributes to metabolic dysfunction-associated steatotic liver disease
(opens in new window)
Author(s):
Kyla Z. Gelev, Seung Hyuk T. Lee, Marcus Alvarez, Rosellina M. Mancina, Federica Tavaglione, Oveis Jamialahmadi, Umberto Vespasiani-Gentilucci, Asha Kar, Zitian Wang, Dorota Kaminska, Minna U. Kaikkonen, Ville Männistö, Sini Heinonen, Tuure Saarinen, Anne Juuti, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Stefano Romeo, Päivi Pajukanta
Published in:
Nature Communications, Issue 17, 2026, ISSN 2041-1723
Publisher:
Springer Science and Business Media LLC
DOI:
10.1038/S41467-026-73660-6
Adipose single cell epigenome and transcriptome localize genetic risk for cardiometabolic disease and accelerated aging
(opens in new window)
Author(s):
Seung Hyuk T. Lee, Asha Kar, Kyla Z. Gelev, Zeyuan Johnson Chen, Sankha Subhra Das, Sini Heinonen, Tuure Saarinen, Maija Vaittinen, Dorota Kaminska, Hilkka Peltoniemi, Chongyuan Luo, Anne Juuti, Ville Männistö, Jussi Pihlajamäki, Minna U. Kaikkonen, Kirsi H. Pietiläinen, Brunilda Balliu, Päivi Pajukanta
Published in:
Nature Communications, Issue 17, 2026, ISSN 2041-1723
Publisher:
Springer Science and Business Media LLC
DOI:
10.1038/S41467-026-72248-4
Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype
(opens in new window)
Author(s):
R. Noah Perry, Graham Lenert, Ernest Diez Benavente, Aydin Bölük, Rebecca Hernandez, Lijiang Ma, Nicolas Barbera, Kelsey Watts, Victor D. Mendoza, Tiit Örd, Mari Taipale, Nadja Sachs, Jessica Pauli, Michal Mokry, Dominique P.V. de Kleijn, Menno P.J. de Winther, Manuel Mayr, Lars Maegdefessel, Karen Reue, Minna U. Kaikkonen, Johan L.M. Björkegren, Hester M. den Ruijter, Mete Civelek
Published in:
Circulation Research, Issue 138, 2026, ISSN 0009-7330
Publisher:
Ovid Technologies (Wolters Kluwer Health)
DOI:
10.1161/CIRCRESAHA.125.326941
