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IMProving User experience, Long-term sustainability and Services of EU-OPENSCREEN

Objective

EU-OPENSCREEN (EU-OS), the distributed European Research Infrastructure for Chemical Biology and early drug discovery, provides world-class services in high-throughput compound screening and medicinal chemistry to users from academia and industry. As one of the largest open-access initiative globally, EU-OPENSCREEN plays an increasingly important role in facilitating early stage drug discovery in Europe. It recently integrated fragment-based drug discovery and chemoproteomics as two new services, but the increasing complexity of modern drug discovery projects requires an even more comprehensive portfolio and integration of emerging technologies. To ensure that EU-OS continues to offer a comprehensive suite of relevant services and support a growing user community to conduct forefront research, IMPULSE will develop, validate and integrate new services in AI/ML, new chemical modalities, and innovative disease-relevant cell models combined with CRISPR-Cas9/RNAi-based genetic screening. IMPULSE will work towards the implementation of common operational and data standards to increase data reproducibility and FAIRness. Bespoke outreach and training activities will raise awareness among key user groups of its new services and advance operational excellence and reproducibility in pre-clinical drug discovery. New models for pre-competitive drug discovery with industry or charities, and growing ERIC member community will reinforce the sustainability and accessibility of EU-OPENSCREEN.

Fields of science

Keywords

Programme(s)

Topic(s)

Call for proposal

HORIZON-INFRA-2023-DEV-01

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Funding Scheme

HORIZON-RIA - HORIZON Research and Innovation Actions

Coordinator

EUROPEAN INFRASTRUCTURE OF OPEN SCREENING PLATFORMS FOR CHEMICAL BIOLOGY EUROPEAN RESEARCH INFRASTUCTURE CONSORTIUM (EU-OPENSCREEN ERIC)
Net EU contribution
€ 1 562 800,00
Address
ROBERT-ROSSLE-STR. 10
13125 Berlin
Germany

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Region
Berlin Berlin Berlin
Activity type
Research Organisations
Links
Total cost
€ 1 953 500,00

Participants (24)

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Last update: 3 November 2023

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Permalink: https://cordis.europa.eu/project/id/101132028

European Union, 2024