Objective
Liverworts, an ancient group of land plants, are a rich and yet still underexploited source of a wide range of biologically active compounds with high potential for the bioeconomy sector as ingredients of cosmetics/cosmeceuticals and pharmaceutics. However, their slow growth rate in nature and the consequent difficulty to obtain large amounts of single compounds have until now severely hindered the in-depth exploration and exploitation of the full spectrum of activities of liverworts secondary metabolites. Recent breakthroughs in the identification of some of the genes involved in the early steps of liverwort-specific compounds suggest that, in addition to the establishment of improved methods for growth in axenic conditions, reconstruction of liverwort metabolic pathways in heterologous systems is a promising way forth towards the practical exploitation of liverwort biochemical diversity and its industrial scale up.
The BRYOMOLECULES project will use a combination of cultivation of axenic cultures and production of the active compounds in heterologous systems to define the most suitable production platform(s) for their large-scale production. The project will achieve a very sustainable use of the chemical diversity of wild EU bryophyte species, a largely untapped source of high added-value natural products, without significant impacts on their biodiversity.
Besides the identification of relevant lead compounds for cosmetics/cosmeceuticals and pharmaceutics , another major impact of the project will be the production and release according to FAIR principles of a database of metabolites and biosynthetic genes of European bryophyte species that will fuel in the years to come the development of novel bio-based products based on bryophyte-derived lead compounds, according to the concept of EU valorizing biodiversity for EU bioeconomy.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.2.6 - Food, Bioeconomy Natural Resources, Agriculture and Environment
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-RIA - HORIZON Research and Innovation Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-CL6-2023-CIRCBIO-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
38098 San Michele All'Adige
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.