Project description
Revolutionising cardiovascular health, one link at a time
Each year, over 6 million new cases of cardiovascular disease (CVD) plague the EU, claiming 1.8 million lives and straining healthcare systems. The lack of effective preventive interventions exacerbates this crisis, burdening both patients and society. In this context, the EU-funded CVDLINK project aims to harness a privacy-by-design European-wide federated platform. It aims to integrate disparate data sources, offering personalised interventions. Specifically, CVDLINK integrates diverse data sources securely, enabling tailored interventions. It offers AI-driven precision medicine tools for diagnosis and treatment, addressing seven cardiovascular conditions across seven countries. Prospectively validated in five nations, CVDLINK promises significant benefits for health systems and citizens. With best practices and cost-effectiveness analyses, it aims for widespread adoption, heralding a new era in CVD care and prevention.
Objective
In the EU more than 6 million new cardiovascular disease (CVD) cases are reported yearly, along with 1.8 million related deaths, posing a substantial burden on the national healthcare systems and society in general. Development of effective preventive interventions, adopted for each individual and population, will not only reduce the overall cost of patient management, but will also justify the assertion that CVDs could be ultimately prevented and controlled. The exploration of existing clinical, genetic and real-world data sources can contribute to this direction, however several challenges related to the data availability, management and processing remain open.
The 48-month project CVDLINK aims to tackle these challenges by implementing a privacy-by-design European-wide federated platform-as-a-service (PaaS) for the delivery of effective data-driven human-centric interventions and the advancement of research and management in the CVD domain. CVDLINK is based on two major offerings: (1) the seamless and legally compliant linking and integration, secure sharing and automated curation of existing data; and (2) a set of AI and data-enabled precision medicine tools and pipelines, for better diagnosis, risk stratification and treatment.
In the context of the project, 7 different cardiovascular conditions will be examined, making use of different retrospective datasets, cohort studies and biobanks from 7 counties, aiming to set a paradigm of the how heterogeneous data sources, can be effectively exploited for building comprehensive AI-driven tools, in order to bring substantial benefits for health systems, patients, industry and EU citizens. The developed tools will be prospectively validated in 5 countries, demonstrating the impact of CVDLINK. Additionally, a set of best practices will be generated, which along with a cost-effectiveness analysis, and systematic raising awareness campaigns will promote its wide adoption in the mid-term.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.2.1 - Health
MAIN PROGRAMME
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HORIZON.2.1.5 - Tools, Technologies and Digital Solutions for Health and Care, including personalised medicine
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-RIA - HORIZON Research and Innovation Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-HLTH-2023-TOOL-05
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
013685 BUCURESTI
Romania
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Participants (18)
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20009 Donostia San Sebastian
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33100 TAMPERE
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546 36 THESSALONIKI
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33520 Tampere
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DUNDALK LOUTH
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64289 DARMSTADT
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33200 TAMPERE
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15 125 MAROUSI
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57 001 THERMI THESSALONIKI
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3810101 HADERA
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9101002 Jerusalem
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
20148 Hamburg
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020021 BUCURESTI
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2025 CHISINAU
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136 74 ACHARNES
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
LT-44029 Kaunas
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51005 TARTU
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1060 Wien
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.