Project description
Decoding early animal evolution
Understanding how different species originated and diverged provides crucial insights into the complexity and diversity of life. Regarding the evolution of the nervous, muscular, and digestive systems, it is not clear whether the common ancestor of animals possessed complex systems, or whether these systems evolved later. With the support of the Marie Skłodowska-Curie Actions programme, the OriGAMA project aims to tackle the fundamental question of which group, sponges or comb jellies, represents the first major split in the animal evolutionary tree. The project focuses on using phylogenomics, comparative genomics, and metagenomics to reconstruct and expand the animal tree of life. Alongside information on conserved metabolic networks, OriGAMA findings will also provide new insights into the metabolism of animals' last common ancestor.
Objective
One of the most fundamental questions in evolutionary biology is centred on our ancestors: How did animals originate? Recent advances in various disciplines have refined this question of whether the most profound divergence in the animal phylogenetic tree, estimated to have occurred approximately 800 million years ago, was between the sponges (Porifera) or the comb-jellies (Ctenophora), and this remains a contentious point of discussion within the scientific community. This is important as it influences our understanding of the evolution of the nervous, muscular and digestive systems. Did the ancestor of all animals already possess complex systems, or did these systems evolve at a later stage? The project described in this proposal aims to answer this question through multiple crucial steps, firstly by improving the genomic quality data from the animal clades in contention and their closest relatives, then by applying innovative and state-of-the-art phylogenomics, comparative genomics and molecular dating techniques, and thirdly through harnessing the power of hidden diversity in the environment through metagenomics. We will use our novel high-quality data to infer the animal tree of life, and importantly, to reconstruct the gene content and metabolism of their last common ancestor. Thanks to the use of complete sets of proteins, we will be able to address this question, for the first time, from a higher hierarchical level, rather than merely looking at the differences between gene histories. We can use our inference of these interacting metabolic networks, which are more conserved across deep time, to understand the evolution of the group and reconstruct the metabolism of the last common ancestor of animals.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- natural sciencesbiological sciencesgenetics
- humanitieshistory and archaeologyhistory
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
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Keywords
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European FellowshipsCoordinator
08007 Barcelona
Spain