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Semiclassical Spin Dynamics in Condensed Phase

Project description

Hybrid quantum-classical mechanics descriptions of NMR spin dynamics

Quantum mechanical spin dynamic calculations for nuclear magnetic resonance (NMR) applications become extremely complex for large spin systems. Semiclassical approximations of spin dynamics calculations are well-established in the fields of radical chemistry and optical spectroscopy, but have been underexplored in the field of NMR. With the support of the Marie Skłodowska-Curie Actions programme, the SCSD project aims to explore semiclassical molecular dynamics as an approximation to quantum mechanical spin dynamic calculations for NMR purposes. This approach will combine quantum mechanical descriptions of smaller systems and classical descriptions of the large nuclear surroundings, the latter enabling computational cost to increase linearly, rather than exponentially with the number of nuclei.

Objective

Quantum mechanical, spin dynamic calculations for NMR purposes, rapidly becomes very complicated when the studied spin systems increase in size. In this project we aim to study methods in which semiclassical molecular dynamics are explored to tackle this problem. Methods for semiclassical approximations have since long times been established within the fields of radical chemistry and optical spectroscopy research but are little explored within the field of NMR. We intend to explore methods where in addition to a smaller completely quantum mechanically described spin systems are investigated, the complete (large) nuclear surrounding is included in a classical manner. More specifically we will add Hamiltonian terms of the Caldeira-Leggett type and eventually simulate the anharmonic environment with ab initio molecular dynamics or empirical force fields. The benefit of the proposed strategy is that matrix size increases linearly with the number of nuclei included instead of exponentially if the environment can be described classically. This will be done by a step by step project plan in which during the earlier work packages investigations of spin systems without the environment included is done. Then once, we have established suitable quantum dynamics methods, we will proceed to include the environment. If this succeeds and we manage to correctly calculate spin dynamics with the impact of the environment in terms of relaxation taken into account, we will continue to the later work packages and try to use this to aid NMR pulse design. If this is successful, this project will open doors to more efficient NMR simulations and provide quantum physical insights to NMR dynamics.

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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

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(opens in new window) HORIZON-MSCA-2023-PF-01

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Coordinator

UNIVERSITA DEGLI STUDI DI MILANO
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 172 750,08
Address
Via Festa Del Perdono 7
20122 Milano
Italy

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Region
Nord-Ovest Lombardia Milano
Activity type
Higher or Secondary Education Establishments
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Total cost

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