Project description
Improving the sensitivity of chirality detection
Circular dichroism (CD) spectroscopy is used to characterise the macromolecular structure of chiral (asymmetric) molecules based on the different absorbance of left and right circularly polarised light. Optically active chiral molecules preferentially absorb one or the other. It is widely used to characterise large molecules such as proteins and DNA. However, many molecules produce weak CD signals below the measurable limit. Plasmonic nanoparticles are extremely strong absorbers and transmitters of light and their interactions with other molecules could amplify their CD signals. With funding from the Marie Skłodowska-Curie Actions programme, the NanOptCD project aims to support their use via theoretical characterisation of plasmonic CD enhancement, analytical tools, and customised nanoparticles.
Objective
NanOptCD aims to facilitate the sensitive use of plasmonic enhanced circular dichroism (CD) spectroscopy in research & development (R&D). Many molecules possess weak CD signals below the measurable limit. Interactions of molecules with plasmonic nanoparticles are very promising for generating strongly enhanced CD signals. Nevertheless, this enhancement mechanism needs further theoretical characterisation in order to facilitate mature applications in R&D. NanOptCD will offer this by analysing the fundamental dependencies of plasmonic CD enhancement with ab initio calculations. Furthermore, NanOptCD will deliver tools for the analysis of plasmonic enhanced CD spectra and customised nanoparticles for optimal plasmonic enhanced CD spectra.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- engineering and technologynanotechnologynano-materials
- natural sciencesphysical sciencesopticsspectroscopy
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Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European FellowshipsCoordinator
02150 Espoo
Finland