Objective
Diatoms are a large group of unicellular, eukaryotic microalgae that biosynthesize SiO2 (silica)-based cell walls (frustules). They are ubiquitously present in aquatic habitats and key primary producers in the oceans, contributing 20% of the annual photosynthetic CO2 fixation on earth. The architectures of frustules are species specific, displaying intricate patterns of nano- and microscale features, and are believed to be of prime importance for the ecological success of diatoms. Furthermore, in biomineralization research, diatoms serve as model systems to reveal the mechanisms by which organisms are able to generate inorganic materials with complex architectures. Such insight holds the promise of gaining advanced capabilities to synthesize minerals with tailored properties using an environmentally benign processes. During the past two decades, numerous candidate proteins potentially involved in diatom silica biogenesis have been put forward, but only a small number of these have been confirmed to be required for this process. The DiaMorphy project aims to identify the complete set of proteins required for silica morphogenesis in the model diatom Thalassiosira pseudonana. To achieve this, the project will inverse the conventional approach by analyzing silica biogenesis in induced morphological mutants of T. pseudonana rather than in the wild-type. For the first time, single-cell transcriptomics will be applied to study gene expression at specific stages during silica biogenesis. Comparative analysis of the resulting, highly refined transcriptomics datasets, is expected to 'crystallize' a comprehensive core set of silica morphogenesis genes. In proof-of-principle experiments, selected proteins from this core set, will then be functionally characterized in vivo using state-of-the art genetic engineering techniques.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2023-PF-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
01069 DRESDEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.