Project description
Linking speech patterns to dementia risk
Mild cognitive impairment (MCI) presents a puzzling middle ground between normal ageing and dementia. Patients with MCI exhibit relatively intact daily functioning but struggle with certain neuropsychological tasks, making it a recognised risk factor for dementia. One hallmark is narrative perseveration (repeated retelling of personal stories), yet its links to neural activity remain poorly understood. Supported by the Marie Skłodowska-Curie Actions programme, the NEUROCOG project will explore the association between types of narrative perseveration in MCI and their unique neural oscillatory profiles. Overall, the project seeks to shed light on how these features vary among MCI subtypes. This approach could ultimately enhance diagnostic precision and deepen understanding of the transition to dementia.
Objective
The goal of the proposal is to identify the association of different narrative perseverations features in mild cognitive impairment (MCI) subtypes with their neural oscillatory profiles. MCI patients show moderately impaired performance on neuropsychological tests but relatively intact global cognition and daily functioning. Validated as different from both normal ageing and dementia, MCI is a risk factor for the development of dementia. The evolving profile to dementia of MCI subtypes is a largely debated issue. MCI patients typically show narrative perseverations in conversations, i.e. reiterations of their own previous narrations. According to literature, perseverations have been studied as test responses in the context of dementia but have not been systematically explored as speech of MCI patients. Recent studies suggest that different oscillatory responses can be observed in different MCI subtypes. However, no effort has been attempted so far to relate such oscillation profiles to linguistic patterns in the speech production of MCI patients. The present action is, therefore, to investigate whether different narrative perseveration subtypes can be associated with distinct neural patterns (oscillatory profiles).
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
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Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-TMA-MSCA-PF-GF - HORIZON TMA MSCA Postdoctoral Fellowships - Global FellowshipsCoordinator
35122 Padova
Italy