Objective
Climate change and increasing exposure to environmental stress make adaptation and defence responses to one of the most significant factors for crop yield and quality. At molecular level, stress-inducible master regulators and key transcription factors translate the stress-signalling into defence and developmental responses at the level of chromatin and gene expression. The dual function transcription factor YIN YANG 1 (YY1) is evolutionary conserved between animal and plant kingdom. In Arabidopsis, the ABA-inducible YY1 is a negative regulator and key component of ABA responses, contributes to the plant resistance to fungal infection and UV-B radiation, and controls flowering time. Some stress related functions of YY1 are conserved between Arabidopsis and Populus tree. Published and the preliminary data indicate that the stress-inducible YY1 in Arabidopsis is a hub that converts stress-signals into defence and developmental responses through interaction with transcription and epigenetic factors controlling common target genes. However, neither the protein-protein interactome nor the direct target genes of YY1 were intensively investigated. On the level of protein-protein interactome of YY1, the comparison of published YY1-Flag IP-MS data with the preliminary Y2H screen data did not find any overlap, although both groups of YY1 interaction candidates contained transcription and epigenetic regulators. These findings and theoretical considerations suggest that large parts of the 'dark interactome' of YY1 wait still to be discovered. Regarding the direct target genes, the proposed ChIP-Seq approaches are the first attempt to study YY1-DNA binding at a global scale. The anticipated results will have a deep impact on understanding of the complex protein-protein interactome of YY1, will identify the direct target genes of YY1, and will contribute to the development of applied approaches in crop plants that could benefit from optimised stress responses orchestrated by YY1.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences infectious diseases
- agricultural sciences agriculture, forestry, and fisheries agriculture
- natural sciences earth and related environmental sciences atmospheric sciences climatology climatic changes
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2023-PF-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
40225 Dusseldorf
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.