Rapid Affordable Microbiota Analysis at the point of Need

Descripción del proyecto

Análisis de la microbiota en tiempo real para la medicina de precisión

El auge de la medicina de precisión y la destrucción en curso de los ecosistemas microbiológicos debido al calentamiento global han puesto de relieve la necesidad de un análisis de la microbiota rápido y en tiempo real. Los métodos actuales, como el cultivo, la metagenómica y la proteómica, son inadecuados para su uso inmediato en momentos críticos. Esto dificulta las intervenciones oportunas, sobre todo en los ámbitos de mayor importancia como la sanidad y la producción ecológica. A medida que el mercado de la microbiota se expande rápidamente, crece la demanda de tecnologías más rápidas y eficaces. El equipo del proyecto RAMAN, financiado por el Consejo Europeo de Innovación, pretende dar respuesta a esta necesidad mediante el desarrollo de un dispositivo para el análisis rápido y asequible de la microbiota en el punto de atención (RAMAN, por sus siglas en inglés). Este dispositivo proporciona resultados exhaustivos en sólo diez minutos, centrándose en aplicaciones cruciales como la microbiota vaginal y de fermentación.

Objetivo

With the pressing demand of precision medicine and the catastrophic damage to microbiological ecosystems following organic processing and global warming, there is a critical need to rapidly characterise microbiota directly at the point of need and observe their potential drifts in real time to correct them in a timely manner. We recently observed an explosive growth of the microbiota market (+30% CAGR) with analyses relying on culture, metagenomics, or proteomics. However, all the available solutions are far too long to process and unadapted to operate at the point of need.
BforCure has developed the first device ever enabling Rapid, Affordable Microbiota Analysis at the point of Need (RAMAN) for a comprehensive microbiota test result in just 10 min.
The RAMAN project aims at 1) Maturing technologies from TRL4 to TRL 6, 2) developing two microbiota universal tests for vaginal microbiota (critical during deliveries with 4% of problematic births worldwide) and fermentation microbiota (responsible for the loss of up to 25% of the production with organic transformation).
Strong demand from end-users and increasing legislation on the spread of microbiological risks make this an ideal time for our project. BforCure has developed a set of 4 breakthrough micro-nano-bio technologies that, once combined, unlock for the first time the possibility of bringing microbiota tests at the Point of Need giving a strong competitive advantage on a €11.9B market.
BforCure is a dynamic company which has already demonstrated the successful development and commercialization of a microfluidic medical device in just 3 years. Our direct contact with the market and our agility of development make us the perfect team to build market-driven products with disruptive technologies which is crucial to create new markets.
Once industrialised, our solution will enable BforCure and its customers to harness the power of the microbiota in many other contexts in health, agri-food industry, and wellness.